30 closest matches · ranked by relevance
Healthy Participants
Primary: Percentage of Total Radiocarbon (14C) Excreted in Urine — 11.9; 20.7 Percentage of 14C in urine
Healthy
Primary: Rate of Iron Excretion. — 1.07; 1.69; 1.08 milligrams per day — p=< 0.05
Fluid Loss · Blood Loss
Primary: Impact of Subject Positioning on Percent Change of Heart Rate (HR) After Minor Blood Loss (e.g., 500mL) — 10.7; 14.7 percent change
Healthy Elderly
Primary: Total Body Water — 1.85 liter
Obesity and Hypogonadism
Primary: Change in the Physical Performance Test — 4.6; 4.9 units on a scale — p=0.58
Intraosseous Vascular Access
Primary: Occurrences of Extravasation During Infusion — 2 participants
Obesity · Endothelial Dysfunction · Decreased Vascular Flow
Primary: Myocardial Perfusion Reserve Measured by Quantitative Perfusion MRI (Ratio of Myocardial Blood Flow During Stress Over Myocardial Blood Flow at Rest) — 2.25; 2.44 ratio…
Healthy Participants
Primary: Total Recovery of Radioactivity in Urine as Percentage of Total Radioactive Dose of PF-06865571 Administered — 48.9; 51.5 Percentage of Dose
Mobility Limitation
Primary: Change in Lean Body Mass as Measured by Dual Energy X-ray Absorptiometry (DXA) — 0.14; 0.74; 4.43; 4.13 kg
Prediabetes · Obesity
Primary: Total Short Physical Performance Battery (SPPB) Score at Baseline — 9.5; 9.6 score on a scale
Hypogonadism, Male · Physical Activity · Testosterone Deficiency
Primary: Change From Baseline in Lean Mass — 2734; 499; 2268 grams
Healthy Volunteers
Primary: Resting Energy Expenditure at Low Temperature — 1.277; 1.134; 1.300; 1.271 kcal/min
Alzheimer Disease
Primary: Plasma CT1812 Concentration at 96 Hours Timepoint — 0.0000707 μg/mL
Smallpox
Primary: AUC0-t — 29500 ng*h/mL
Physical Endurance
Primary: Core Muscle Endurance — 530.5 seconds
Healthy
Primary: Whole-body Protein Net Balance — 6.2; 11.8 grams
Hypogonadism
Primary: Incidence of Adverse Events as a Measure of Safety of QuickShot™ Testosterone (QST) Administered Subcutaneously (SC) Once Each Week to Adult Males With Hypogonadism…
Healthy Participants
Primary: Cohort 1: Number of Participants With Treatment Emergent Adverse Events (TEAEs) — 5; 8; 6; 8 Participants
Healthy
Primary: The Mean (SD) Amount of [14C] Recovered in Urine, as a Percent of the Total [14C] Dose Administered — 25.2 percentage of dose
Healthy
Primary: Change in Serum Pro-collagen 1 Intact N-terminal Propeptide (P1NP) — 72.1; 67.4 ng/mL — p=0.53
Hypogonadism
Primary: Change From Baseline to End of Treatment (EOT) in 24-hour Average Systolic Blood Pressure (SBP) — 1.9 mmHg
Eating Behavior · Eating Habit
Primary: Change in Brain Response From Baseline to 2-weeks Post High UPF or 2 Weeks no UPF Diet — 0.02; 0.13 arbitrary units
Hypogonadism
Primary: Cmax-am for Oral TU Across Breakfast With Varying Fat Content — 250.7; 334.7; 529.7; 506.0 ng/dL
Hypogonadism
Primary: Change From Baseline in 24-hour Average Systolic Blood Pressure (SBP) Obtained at Week 16 — 123.2; 3.5 millimeters of mercury (mmHg)
Healthy Adult Subjects
Primary: Number of Participants With Adverse Events (Aes) and Adverse Drug Reactions (ADRs) — 0; 2; 3; 0 Participants
IV Contrast Dosing
Primary: Difference in Enhancement of the Liver and Blood Vessels Over Time, Measured in Hounsfield Units (HU) — 116; 124; 121; 120 Hounsfield units (HU)
Fluid Loss
Primary: Change in the Relative Index (RI) After Minor Blood Loss (e.g., 500mL) — 2.9 Percent change in RI
Hypogonadism · Severe Obesity
Primary: Percent Change in Muscle Strength as Assessed by Knee Extension and Knee Flexion — 12.6; 8.9; 12.8; 3.7 Percent change in muscle strength
Hypogonadism, Male
Primary: Change From Baseline in 24-hour Average Ambulatory Systolic Blood Pressure After 120 Days Treatment — 128.9; 130.6; 1.7 mmHg
Healthy Participants
Primary: Number of Participants Reporting Treatment-Emergent Adverse Events (TEAEs) — 1; 2; 3; 2 Participants