N/A N=34 Heat Acclimation, Hand Cooling Efficacy, and Adaptation Maintenance.
Heat
Primary: Internal Body Temperature — 39.6; 38.2 degrees Celcius
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=22 Local Heat Stress in Autonomic Failure Patients With Supine Hypertension
Hypertension · Pure Autonomic Failure · Multiple System Atrophy
Primary: Change in Systolic Blood Pressure — 19; 3 mm Hg
N/A N=41 Cardiovascular Responses to Heat Waves in the Elderly
Aging · Hyperthermia
Primary: Change in Core Body Temperature — .68; 1.37; .58; 1.02 degrees Celsius (°C)
Phase 2 N=34 Efficacy and Safety of Ryanodex® (EGL-4104) as Adjuvant Treatment in Subjects With Exertional Heat Stroke (EHS)
Heat Stroke
Primary: Number of Subjects Achieving Recovery of Level of Consciousness Defined as a Glasgow Coma Scale (GCS) GCS ≥ 13 — 5; 2 Participants — p=0.396
N/A N=65 Exercise in Burn Survivors: Cooling Modalities
Burn Injury
Primary: Change in Core Temperature (°C) During Control Intervention — .578; .920; .622; .885 °C
N/A N=15 A Novel Cooling Vest to Protect Persons With SCI From Hyperthermia
Spinal Cord Injuries
Primary: Skin Temperature (Tsk) Change — -5.6; -6.9; 2.1 Degrees Celsius — p=0.002
N/A N=21 Body Temperature in Persons With Tetraplegia When Exposed to Heat
Spinal Cord Injury
Primary: Core Body Temperature — 2.04; -0.05 Percent Change — p=0.0001
Phase 3 N=17 Study to Assess the Efficacy and Safety of Ryanodex as Adjuvant Treatment in Subjects With EHS
Exertional Heat Stroke
Primary: Cumulative Incidence of Recovery of Level of Consciousness Defined as a Glasgow Coma Scale (GCS) GCS ≥ 13 [Time Frame: 90 Minutes Post-randomization] — 4; 2 Participants
N/A N=30 Cooling Vest May Reduce Heat Stress During Surgery
Body Temperature Changes
Primary: Self-rated Thermal Comfort. — 4.4; 6.6 score on a scale — p=<0.001
Phase 4 N=12 The Influence of Menthol Gel During Exercise With Heat
Acute Exercise · Heat Exposure
Primary: Skin Blood Flow — 131.6; 119.2 arbitrary units — p=0.742
N/A N=41 Effect of Heat Exposure on Cognition in Persons With Tetraplegia
Tetraplegia · Hypothermia · Mild Cognitive Impairment
Primary: Change in Core Body Temperature From Baseline to 120 Minutes Post Warm Challenge — 0.59; -0.05 degrees Centigrade
Phase 4 N=12 The Influence of Capsaicin Gel During Exercise Within the Heat
Acute Exercise · Heat Exposure
Primary: Skin Blood Flow — 188.4; 139.2 arbitrary units — p=0.284
N/A N=170 Stressor-evoked Brain and Cardiovascular Responses to Acute Psychological Stress
Acute Psychological Stress
Primary: Stressor-evoked Oxygen Consumption in mL/(kg·Min) (Stress - Baseline) — 0.265; 0.287 mL/(kg·min)
N/A N=124 Enhanced Firefighter Rehab Trial: The Role of Aspirin in Preventing Heat Stress Induced Platelet Activation
Heat Stress Disorders
Primary: Platelet Closure Time — 275.5; 207; 95; 90 seconds
Phase 3 N=80 Post Traumatic Stress Disorder (PTSD) Hyperarousal Symptoms Treated With Physiological Stress Management
Stress Disorders, Post-Traumatic
Primary: Change Scores for Criteria D Items on the CAPS Structured Clinical Interview — -1.20; -6.27 units on a scale — p=.27
N/A N=1,189 Fire Fighter Fatigue Management Program: Operation Healthy Sleep
Shift-Work Sleep Disorder · Insomnia · Restless Leg Syndrome
Primary: Firefighters' Health, as Determined by Number of 'Sick' Days Over 12 Months — 3.1; 3.2; 1.4; 2.6 days/firefighter — p=0.66
N/A N=17 Chronic Passive Heating in Individuals With T2DM
Type2 Diabetes
Primary: Insulin Sensitivity — 0.31; 0.33; 0.10; 0.10 AU
N/A N=201 Analysis of Sweat Secretion and Body Dehydration Monitoring
Dehydration
Primary: Number of Measurements Grouped by Level or Error — 48; 48; 49; 50 Number of measurements
N/A N=10 "Facemask Use During High-intensity Interval Exercise in Temperate and Hot Environments"
Hypoxemia · Physiological Stress
Primary: Average Heart Rate Over the Course of High-intensity Interval Exercise — 144; 143; 148; 149 beats per minute — p=0.003
N/A N=35 The Effect of Acute Mild Dehydration on Blood Pressure Control
Mild Dehydration
Primary: Blood Pressure Variability — 2.6; 2.5 mmHg
Phase 2 N=24 Intranasal Cocaine and Temperature Regulation During Exercise
Hyperthermia · Cocaine Use · Exercise
Primary: Change in Core Temperature — 1.19; 1.09; 1.20; 0.89 Celsius