30 closest matches · ranked by relevance
Pain
Primary: Time-weighted Sum of Pain Intensity Difference Scores on 11-Point Numerical Scale From 0 to 24 Hours Post-dose (SPID11 [0-24]) — -8.13; 64.76 units on a Scale — p=<0.001
Pain, Acute
Primary: Pain Reduction at 60 Minutes From Baseline of the 3 Oral Ibuprofen Groups — -2.12; -1.85; -1.96 units on a scale
Fever
Primary: Time Weighted Sum of Temperature Difference (WSTD) From 0 to 8 Hours — 9.28; 12.54; 11.09; 12.39 degrees fahrenheit — p=0.002
Low Back Pain
Primary: Change in Functional Impairment as Measured by the Roland Morris Disability Questionnaire — 11.1; 11.9 units on a scale
Fever
Primary: Child Temperature (Degrees C)Over 6 Hours — 38.5; 37.2; 36.9 degrees Celcius — p=<0.001
Pain
Primary: Summed Pain Intensity Difference Over 0 to 12 Hours (SPID12) After Time 0 — 51.84; 56.33; 19.11 score on a scale*hours — p=<0.0001
Patient Compliance
Primary: Percentage of Participants Taking Greater Than (>) 1200 Milligram (mg) (>3 Caplets) on no More Than 2 Use Days During the Study — 95.2 percentage of participants
Pain · Post-Operative Pain · Third Molar Extraction
Primary: Analgesic Efficacy, as Measured by the Sum of Pain Intensity Differences (SPID) Scale — 14.80; 0.40 Units on a scale — p=<0.0001
Pain
Primary: Pain Severity — 39; 43; 42 mm
Analgesia
Primary: Percentage of Participants Who Correctly Select to Use or Correctly De-select Not to Use Ibuprofen 600 Milligram (mg) Immediate Release (IR) or Extended Release (ER)…
Fever
Primary: Fever Reduction — -1.5; -0.9 degree Celsius*Time
Bioequivalence of the Test Formulation
Primary: Maximum Plasma Concentration (Cmax) of Ibuprofen — 38.503; 25.162; 33.843; 26.432 μg/ml
Pain, Postoperative
Primary: Heft Parker Visual Analog Scale Pain Scale Pain Measurements — 63; 60 units on a scale
Post-operative Pain
Primary: Change From Baseline in Area Under the Curve (AUC) of Pain Intensity and Relief Scores (SPRID) — 2.68; 3.30; 2.62; 1.93 units on a scale*hour — p=<0.0001
Back Pain · Neck Pain
Primary: Change in Pain on Movement (POM) With Regard to the Worst Procedure (WP) Between Baseline and Day 2 (Morning, 2 Hours After Drug Intake) — 1.712; 1.998; 1.869 Unit on…
Asthma · Wheezing
Primary: Exacerbation Frequency — 0.81; .87 asthma exacerbations per 46 weeks — p=0.67
Major Depressive Disorder
Primary: Dose-dependent Differences in the BOLD Response to fMRI Tasks in the Amygdala — 0.20; 0.21; 0.23; 0.23 percent signal change — p=0.512
Pain, Postoperative · Tooth Diseases
Primary: Time-weighted Sum of Pain Relief (PAR) and Pain Intensity Difference (PID) From 0 to 8 Hours (SPRID0-8h) — 10.554; 15.824; 40.165; 52.291 units on a scale — p=<0.0001
Post-surgical Pain Following Extraction of Molar Teeth
Primary: Time-weighted Sum of Pain Intensity Difference Scores on 11-Point Numerical Scale From 0 to 8 Hours Post-dose (SPID11 [0-8]) — 4.1; 34.3; 28.9; 19.4 units on a scale…
Pain
Primary: Time-weighted Sum of Pain Relief Rating and Pain Intensity Difference From 0-3 Hours (SPRID 0-3) for Ibuprofen Sodium Versus Placebo Tablet — 9.6; 3.5 units on scale…
Pain · Fever
Primary: Area Under the Curve (AUC) 0-4 Hours of a Single Dose of Intravenous Ibuprofen (IVIb) Administered Over 5-7 Minutes. — 75.74 mcg*hr/mL
Pain
Primary: Time-weighted Sum of Pain Relief and Pain Intensity Difference Scores From 0 to 12 Hours After the First Dose (SPRID 0-12) — 18.2; 41.5 units on a scale — p=<0.001
Low Back Pain
Primary: Change in Pain Disability - Roland Morris Disability Questionnaire (RMDQ) Score — 8.7; 10.1; 6.4 score on a scale
Osteoarthritis, Knee
Primary: Change in Average Pain Intensities Measured From the Pre-Treatment Walk (Baseline) at 3 Post-Treatment Walks — 0.24; 0.18; 0.18 Units on a Scale — p=0.743
Pain
Primary: Change From Baseline in the Time-Weighted Sum of Muscle Soreness With Movement Over 0-24 Hours Post-Dose 1 (MSM 0-24 ) — 22.2; 17.8; 29.7 units on a scale — p=0.200
Gallbladder Disease
Primary: Stress Response Inflammation Markers :Cortisol and C Reactive Protein (CRP) — 173.6; 289.5; 17; 17 pg/mL
Cognitive Impairment · Malignant Neoplasm
Primary: Effects of Ibuprofen on Alleviating Chemotherapy-related Cognitive Impairment — 89.98; 91.08; 105.54; 107.75 score on a scale — p=0.7917
Biliary Colic
Primary: Pain Score 120 Minutes After Study Medication Administration — 3.0; 0.3 score on a scale
Pain
Primary: Efficacy of Pain Relief (Pain Intensity at Rest) — 30; 32 units on a scale (in mm)
Pain
Primary: Time-weighted Sum of Pain Intensity Difference Score From 0 to 12 Hours (SPID 0-12) — 0.05; 16.87; 17.34; 12.66 units on a scale — p=<0.001