30 closest matches · ranked by relevance
Dyspareunia · Vaginal Dryness
Primary: Female Sexual Function Index (FSFI) Score Compared to Baseline — 4.14; 5.95 score on a scale
Erythema · Edema
Primary: Number of Subjects With Observed Local Erythema Based on the 5 Point Scoring Scale — 0 Participants
Erythema · Edema
Primary: Number of Subjects With Observed Local Erythema Based on 5 Point Scale — 0 Participants
Erythema · Edema
Primary: Number of Participants With Adverse Events as a Measure of Safety and Tolerability — 0 participants
Erythema · Edema
Primary: Number of Patients That Showed Sensitization Reaction to the Test Material at Challenge — 0 Participants
Dry Eye Syndrome · Tear Film Insufficiency
Primary: Change From Baseline (V2) in Frequency and Severity of Dry Eye Symptoms (SANDE) Questionnaire Scores at Day 28±4 (End of Treatment) — -11.9; -16.6; -25.0; -26.5 mm
Erythema · Edema
Primary: Number of Participants With Observed Local Erythema — 0 participants
Dry Eye Syndrome
Primary: Change From Baseline in Foreign Body Sensation, Burning/Stinging, Itching, Pain, Stick Feeling, Blurred Vision, Photophobia and Total Ocular Tolerability Score (VAS)…
Pelvic Floor Disorders
Primary: Pain During the Pelvic Floor Examination — 0.4; 0.9; 1.3; 3.6 units on Wong Baker pain scale
Refractive Error
Primary: Average Coefficient of Friction of Worn Lenses at 16 Hours — 0.0602; 0.0576; 0.0578 unitless
Examination, Gynecological · Examination, Pelvic · Examination, Vaginal
Primary: Patient Discomfort During Speculum Insertion as Measured by a Visual Analog Scale. — 1.41; 2.15 score on a scale
Menopause Related Conditions · Postmenopausal Symptoms
Primary: Efficacy of VR101 Treatments at 28 Days Assessed by Change in VHI (Vaginal Health Index) Scores Assigned by Clinicians — 1.76; 0.55; 1.38; 0.97 Score on a Scale
Lid Wiper Epitheliopathy
Primary: Lid Wiper Epitheliopathy — 0.63; 0.25 score on a scale
Coitus
Primary: Number of Participants Showing Change From Baseline in Irritation Scores — 0; 0 Participants
Inadequate Lubrication
Primary: Number of Participants With Physical Irritation Scores — 61; 61; 1; 0 Participants
Sexual Dysfunction · Breast Cancer Survivors
Primary: Change of Pain Score of Female Sexual Function Index — 1.15; 1.05 units on a scale
Ocular Discomfort
Primary: Changes From Baseline (Day 1 Pre-dose) in Ocular Tolerability Using a Visual Analogue Scale (VAS) — -22.8; -30.1; -20.9; -20.9 mm — p=0.3474
Constipation
Primary: Change of Mucus and Mucin Secretion in Patients With Chronic Constipation and in Controls. — 260; 133; 229; 161 mg/hour
Dry Eye
Primary: Drop Comfort Upon Instillation — 1.7; 1.3 Units on a scale
Dry Eye
Primary: Tear Lipid Layer Thickness — 0.72; -7.58; 2.06; 1.41 nm
Erythema · Edema
Primary: Number of Participants With Observed Local Erythema — 0 participants
Lubricating Agents
Primary: Number of Subjects With Irritation Score of "0" at Baseline and One Week — 35; 35; 35; 35 Participants
Refractive Error
Primary: Average Coefficient of Friction (CF) at 16 Hours Compared to Unworn — 0.0394; 0.0396 unitless
Dry Eye Syndromes
Primary: Mean Frequency of Eye Drop Use Over 1 Week — 1.76; 1.66 Use per day
Dry Eye Disease
Primary: Change From Baseline in Impact of Dry Eye on Everyday Life - Symptom Bother (IDEEL-SB) Questionnaire Score at Day 30 — -16.95 score on a scale — p=<.0001
Dry Eye
Primary: Drop Comfort Upon Instillation — 1.1; 1.4 Units on a scale
Sexual Dysfunction, Physiological
Primary: Proportion of Participants With Increased Female Sexual Function Index Lubrication Domain (FSFI-LD) Scores — 57; 43 Participants
Dry Eye Syndrome · Lipid Deficiency
Primary: Mean Bulbar Conjunctival Staining — 0.743; 0.442; 0.531; 0.443 percentage of staining
Dry Eye Syndrome
Primary: Number of Meibomian Glands Yielding Liquid Secretion (MGLYS) — 3.5; 4.2; 7.0; 3.9 functioning glands
Vulvodynia · Dyspareunia · Breast Cancer
Primary: Prevention of Entry Dyspareunia With Non-hormonal Therapy — 5.3; 1.04; NA; 0.57 Units on a scale — p=0.0149