Clinical Trial Search

Primary: Percentage of Subjects That do Not Require Rescue Midazolam (MDZ) for Sedation Based on Achieving and Maintaining a Target University of Michigan Sedation Scale (UMSS)…

Primary: Weaning Time From Mechanical Ventilation — 5; 5 hours — p=0.84

Primary: Bronchial Secretion Volume Over Preceding 24 Hour Period — 220; 310; 200; 70 mL/24 hr

Primary: Percentage of Participants With Nosocomial Pneumonia Caused by Pseudomonas Aeruginosa — 18.1; 12.5; 22.4 Percentage of participants — p=0.491

Primary: Total Number of Deaths in the Pre vs Post-intervention Time Periods Among Study Participants Per 1000 Mechanically Ventilated Patient Days — 72; 73 Deaths per 1000…

Primary: Percentage of Time Spent With Arterial Oxygen Saturation < 75% — 5; 4.4 % of time — p=0.44

Primary: All-cause Mortality — 2269 Participants

Primary: Participant Recruitment — 196; 219 Participants

Primary: Successful Extubation — 58; 222 Participants

Primary: Percentage of Time Sedation Depth is Maintained Within the Target Range, in Absence of Rescue Sedation, as Assessed According to the RASS Scale, in Isoflurane- vs…

Primary: The Percentage of Time Sedation Depth is Maintained Within the Target Range, in Absence of Rescue Sedation, as Assessed According to the RASS Scale, in Isoflurane- vs…

Primary: Change From Baseline in Clinical Pulmonary Infection Score (CPIS) For Each Patient, Value Obtained From a Daily Assessment Over the 10 Day Study Period Was Compared to…

Primary: Percentage of Time of Adequately Maintained Sedation Depth up to 48 Hours (± 6 Hours) — 62.37; 68.94 Percentage of time

Primary: Feasibility — 100; 100 percentage of participants retained

Primary: Measurement of Time to Intubation Will Begin at the Time of Mouth Opening and End With the Removal of the Tip of the Laryngoscope Blade From the Patient's Mouth After…