Clinical Trial Search

Primary: Change From Baseline at Week 6 in Caregiver-rated Aberrant Behavior Checklist Irritability (ABC-I) Subscale Score — -9.6; -11.2; -11.2 score on a scale — p=0.2986

Primary: Mean Change From Baseline to Week 8 in Aberrant Behavior Checklist - Irritability (ABC-I) Subscale Score — -10.1; -8.87 score on a scale — p=0.4597

Primary: Clinical Global Impression Improvement (CGI-AD) — 3.83; 4.25; 2.67; 4.25 score on a scale

Primary: Number of Participants With Treatment-emergent Adverse Events (TEAEs) Graded By Severity, Serious TEAEs and Trial Discontinuation Due to TEAEs — 23; 24; 15; 19…

Primary: Percentage of Patients Relapsing by Week 16 — 32; 50 Percentage of participants — p=0.097

Primary: Change From Baseline in Aberrant Behavior Checklist Irritability Subscale (ABC-I) — -12; -7 units on a scale — p=.44

Primary: Change in Aberrant Behavior Checklist Irritability (ABC-I) Subscale — -3.5; -7.4; -12.4 units on a scale — p=<0.001

Primary: Change in Affective Reactivity Index - Youth (ARI-Y) — -2.9; -0.8 score on a scale

Primary: Change in Maladaptive Behaviors — -6.62; -1.08 units on a scale

Primary: Number of Participants Improved as Measured by the Clinical Global Impression-Global Improvement Scale (Improvement Defined as CGI-I=1 or CGI-I=2) — 11; 3 participants

Primary: Change in Score on Conners Adults Attention Deficit Hyperactivity Disorder (ADHD) Rating Scale — 68.6; 71.8; 53.4; 57 T-score

Primary: Clinical Global Impressions-Improvement — 1.8 units on a scale

Primary: Mean Change (Week 8 - Baseline) in the Autistic Behavior Checklist (ABC) Irritability Subscale Score — -8.4; -12.4; -13.2; -14.4 units on a scale

Primary: Change From Baseline in the Pervasive Developmental Disorder-Behavioral Inventory (PDDBI) - Autism Composite Score — -4.5; -6.4 units on a scale — p=0.5

Primary: Mean Change (Week 8 - Baseline) in the Autistic Behavior Checklist (ABC) Irritability Subscale Score — -5.0; -12.9 units on a scale

Primary: Number of Participants With Improvement on the Clinical Global Impression-Improvement (CGI-I) Scale — 3; 1 Participants

Primary: Change From Baseline in Aberrant Behavior Checklist-Irritability at 12 Weeks — 7.6; -0.6 units on a scale

Primary: Mean Change From Baseline in the Aberrant Behavior Checklist Japanese Version (ABC-J) Irritability Subscale Score — -11.4; -7.5 units on a scale

Primary: Change From Baseline in Parent Rated Social Responsiveness Scale (SRS) Scores During Treatment. — 9.73; 3.18 units on a scale — p=0.0275

Primary: Baseline and Week 8scores on Children's Yale-Brown Obsessive Compulsive Scale - Pervasive Developmental Disorder Version — 12.7; 8.6 Scores on a scale

Primary: Mean 10-Week Change in Pediatric Anxiety Rating Scale 5-Item Total Score, Double-blind Phase — -4.9; -3.2 score on a scale

Primary: Change in Responses to Affective Touch — 3.01; 4.06 units on a scale

Primary: Mean Change From Baseline to Study Endpoint in the Aberrant Behavior Checklist (ABC) Irritability & Agitation Subscale Score. — -14.81; 0.37 score on a scale

Primary: Change in Aberrant Behavior Checklist (ABC) Irritability Subscale Score at Week 6 — 8.8; 9.4; 7.5 units on a scale — p=0.5463

Primary: Percentage of Participants Randomized — 100; 100 percentage of participants randomized

Primary: Number of Participants Who Could Tolerate Twice Daily Oxytocin — 13; 11 Participants

Primary: Mean Threat Processing Bias During Visual Dot-probe Paradigm Over Time — -0.57; 36.92; -9.04; -42.35 attention bias in milliseconds — p=0.160

Primary: Irritability Subscale of the Aberrant Behavior Checklist, Community Version — -8.9 Points on a scale

Primary: The Effects of rTMS on Reciprocal Social Awareness — 68; 79.667; 64.2; 74 total raw score (higher=worse)

Primary: Number of Participants With Serious Adverse Events (SAEs), Treatment-Emergent Adverse Events (AEs), Deaths, AEs Leading to Discontinuation, Extra Pyramidal Syndrome…