N/A N=122 Comparison Between C3-6 Laminoplasty and C3 Laminectomy With Cervical Laminoplasty
Myelopathy Cervical · Kyphosis Post Surgical · Neck Pain
Primary: C2-C7 Lordosis — 11.0; 10.9 °
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=239 Clinical Trial Comparing Decompression With and Without Coflex™ Interlaminar Technology Treating Lumbar Spinal Stenosis
Spinal Stenosis
Primary: Change in ODI From Baseline to 24 Months — -19.0; -22.5 percentage points
Phase 4 N=146 Herniectomy Versus Herniectomy With a Spinal Stabilization System for the Treatment of Complex Disc Disease
Sciatica · Back Pain
Primary: To Demonstrate a Statistically Significant Difference in the Relief of Back Pain Between Both Treatment Groups. The Endpoint Will be the Difference Between Baseline and…
N/A N=92 Epidural Neuroplasty for the Treatment of Herniated Lumbar Disk
Herniated Lumbar Disc
Primary: Pain Assessed by Visual Analogue Scale — 5.63; 5.92 units on a scale
N/A N=40 Percutaneous Diskectomy SpineJet x Open Microdiskectomy in Treatment of Lumbar Radiculopathy
Radiculopathy · Herniated Disk
Primary: VAS for Lumbar Pain in 3 Months — 2.63; 4.53 units on a scale — p=0.05
N/A N=168 The STEPS - Totalis™ Trial
Lumbar Spinal Stenosis
Primary: Percentage of Subjects With Clinically Significant Improvement in Outcomes — 56.3; 56.0 percentage of subjects
Phase 4 N=55 MiDAS II (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study
Lumbar Spinal Stenosis
Primary: Changes in Back Pain as Measured by a 10-point Visual Analog Scale (VAS). — 3.59 units on a scale — p=<0.0001
N/A N=10 The Vertos MILD™ Preliminary Patient Evaluation Study
Lumbar Spinal Stenosis
Primary: Changes in Back Pain as Measured by a 10-point Visual Analog Scale (VAS). — 3.3 units on a scale
Phase 4 N=78 MiDAS I (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study
Lumbar Spinal Stenosis
Primary: Mean Change in Back Pain as Measured by a 10-point Visual Analog Scale (VAS). — 3.21 units on a scale — p=<0.0001
N/A N=5,050 Retrospective Evaluation of Performance of Coflex® Interlaminer Technology Versus Decompression With or Without Fusion
Spinal Stenosis
Primary: Overall Duration of Follow-up Care to Evaluate Overall Effectiveness of the Use of the Coflex® Interlaminer Technology — 201.26; 191.75 days
N/A N=40 Comparative Study of Sham Versus Mild® Procedure in Patients Diagnosed With Symptomatic Lumbar Central Canal Stenosis
Lumbar Spine Stenosis Central Canal
Primary: Visual Analog Scale (VAS) <=4 — 11; 2 participants
N/A N=337 5-Year Global Study on MAST™ Minimally Invasive Fusion Procedures to Treat Degenerative Lumbar Spine (MASTERS-D2)
Intervertebral Disc Degeneration
Primary: Change (Preop-postop) of Disability, Oswestry Disability Index (ODI) at 3 Months as Compared to Baseline in DDD Patients With Spondylolisthesis — 23.19; 26.08 change of…
N/A N=100 Sagittal Plane Shear Index for Planning Lumbar Stenosis Surgery
Lumbar Spinal Stenosis · Spondylolisthesis
Primary: Proportion of Surgical Plans Recorded Prior to the SPSI Report That Are Altered After Integration of SPSI Into the Surgical Planning — 47; 22; 6 Surgical plans
N/A N=100 LSA Reconstruction With Laser Fenestration During the TEVAR
Type B Aortic Dissection
Primary: Freedom From All-cause Reintervention, All-cause Mortality and Major Adverse Events Within 30 Days After Procedure — 84 Participants
N/A N=36 Accell Evo3™ Demineralized Bone Matrix in Instrumented Lumbar Spine Fusion
Degenerative Changes · Stenosis · Spondylosis
Primary: Time to Arthrodesis (Fusion) for Each Spinal Level (Unit), as Measured by X-rays. — 6 months to fusion
N/A N=46 Vertos Mild - Post Market Patient Outcomes
Lumbar Spinal Stenosis
Primary: Pain as Measured by Visual Analog Scale (VAS). — 2.17 units on a scale — p=<0.0001
N/A N=72 Minimal Access Surgical Technique (MAST) in Obese Patients in Degenerative Lumbar Disease
Degenerative Lumbar Disease
Primary: Postoperative Complications in the BMI Groups During Post Operative Hospitalization. — 8; 9; 20 Events during hospitalization
Phase 4 N=38 Study of Epidural Steroid Injection (ESI) Versus Minimally Invasive Lumbar Decompression (Mild®) in Patients With Symptomatic Lumbar Central Canal Stenosis
Lumbar Spinal Stenosis
Primary: Mean Change in VAS — 2.52; 0.06 units on a scale — p=<0.05
N/A N=252 A Prospective, Multicenter Observational Study on MAST™ (Minimal Access Spinal Technologies) Fusion Procedures for the Treatment of the Degenerative Lumbar Spine
Degenerative Lumbar Spine Causing Back and/or Leg Pain · Lumbar Spine Degeneration
Primary: Time From Surgery to First Ambulation. — 1.3 Days from surgery to first ambulation
N/A N=120 Effectiveness of Percutaneous Lumbar Epidural Adhesiolysis and Neurolysis on Low Back Pain
Low Back Pain
Primary: Numeric Pain Rating Score — 7.9; 8.1; 4.9; 3.4 units on a scale — p=<0.001
N/A N=302 The MiDAS ENCORE Study
Spinal Stenosis, Lumbar Region, With Neurogenic Claudication
Primary: Number of Participants Who Achieved a Clinically Significant Improvement in the Oswestry Disability Index at 12 Months — 83; 35 Participants
N/A N=178 Lumbar Degenerative Disc Disease Treated With Anterior Tension Band System (ATB) With ALIF/FRA Spacer
Lumbar Degenerative Disc Disease
Primary: Number of Subjects With Successful Radiographic Fusion — 90 Participants
N/A N=53 Lumbar Fusion With Nexxt Spine 3D-Printed Titanium Interbody Cages
Lumbar Degenerative Disc Disease · Lumbar Spinal Stenosis · Lumbar Spondylolisthesis
Primary: Interbody Radiographic Fusion Rate — 27; 10; 6; 24 Cages/Spinal Levels
N/A N=27 Spinal Cord Stimulation in Patients With Post-Laminectomy Syndrome in Testing Phase
Laminectomy · Post-laminectomy Syndrome · Spinal Cord Syndrome
Primary: Comparing Visual Analogue Scale (VAS) — 9.3; 8.6; 5.7; 4.9 score on a scale — p=0.112
N/A N=376 Activ-L™ Artificial Disc Treatment of Degenerative Disc Disease in the Treatment of Degenerative Disc Disease
Degenerative Disc Disease
Primary: Overall Success at 24 Months Relative to Baseline — 42.2; 28.3; 61.9; 52.8 percentage of participants — p=<0.05
N/A N=20 TRIUMPH Lumbar Artificial Disc IDE: A Pilot Study
Lumbar Degenerative Disc Disease
Primary: Number of Participants With a Change of at Least 15 Points in Pain/Disability Using the Oswestry Disability Index (ODI) Score at 24 Months Compared With the Score at…
Phase 3 N=401 Corticosteroid Lumbar Epidural Analgesia for Radiculopathy
Lumbosacral Radicular Pain
Primary: Mean Change From Baseline (Day 1) to Week 4 in the Mean Numeric Pain Rating Scale (NPRS) Average Pain Score in the Affected Leg — -2.34; -1.16 Change in score on a scale…
Phase 4 N=32 GRASSP: Gralise® for Spine Surgery Pain
Post-laminectomy Pain Syndrome
Primary: Mean Change in Numeric Rating Scale (NRS) — -0.56; -0.54 units on a scale
N/A N=138 MiDAS III (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study
Lumbar Spinal Stenosis
Primary: Percentage of Participants With a 2-point Improvement in Visual Analogue Scale — 65.71; 46.15 percentage of responders
N/A N=58 Study of an Expandable Interbody Device for the Lumbar Spine
Degenerative Disc Disease
Primary: Fusion and Disc Height Maintenance — 11.60 millimetres