N/A N=6 First Study With a Brain Implant to Help Locked-in Patients Communicate at Home
Locked-In Syndrome
Primary: Number of Participants Reaching Proficiency Level 2: Unsupervised BCI Performance — 1 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=20 Feasibility of mindBEAGLE in Disorders of Consciousness or Locked-In Syndrome
Consciousness Disorders · Locked-In Syndrome
Primary: Behavioral Diagnosis of Level of Consciousness (LoC) — 0; 23; 2; 23 score on a scale
N/A N=6 ECoG Direct Brain Interface for Individuals With Upper Limb Paralysis
Tetraplegia · Spinal Cord Injury · Brachial Plexus Injury
Primary: Number of Participants Able to Successfully Control of a Variety of External Devices Using Neural Data Recorded With ECoG — 3 participants
N/A N=1 Reanimation in Tetraplegia
Spinal Cord Injury (Quadraplegia)
Primary: Number of Participants With Voluntary Movement — 1; 0 Participants
N/A N=1 An In-home Study of Brain Computer Interfaces
Amyotrophic Lateral Sclerosis
Primary: Duration of BCI Usage by Persons With ALS. — 5 months
N/A N=1 Restoring High Dimensional Hand Function to Persons With Chronic High Tetraplegia
Spinal Cord Injuries · Tetraplegia · Quadriplegia
Primary: Ability to Form Appropriate Grasp Patterns — 78.75 percentage of correct grasps formed
N/A N=13 A P300 Brain Computer Interface Keyboard to Control Assistive Technology For Use by People With Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
Primary: Accuracy of Typing With a BCI Keyboard by ALS Patients. — 81; 78; 75 percentage accuracy
N/A N=20 A Telerehabilitation Program for SCI
Incomplete Spinal Cord Injury
Primary: Arm and Hand Function as Assessed by Score on the Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP) — 64.9; 58.3 score on a scale
N/A N=1 Providing Brain Control of Extracorporeal Devices to Patients With Quadriplegia
Tetraplegia
Primary: Number of Participants With Patient Control Over the End Effector (Virtual or Physical) — 1 Participants
N/A N=23 Treatment of Chronic Stroke With IpsiHand
Stroke
Primary: Change in Action Research Arm Test (ARAT) Score — 6.2 units on a scale — p=0.002
N/A N=24 Ipsihand Device Use in Stroke Patients to Assess Functional Motor Outcomes
Stroke
Primary: Fugl-Meyer Assessment - Upper Extremity — 9.18 Units on a scale
Phase 2 N=18 Positional Therapy After Stroke
Sleep Apnea · Stroke
Primary: Apnea-hypopnea Index — 27; 39 events/hr — p=0.011
Phase 4 N=60 SISTERS: Spasticity In Stroke Study - Randomized Study
Severe Spasticity
Primary: Change in Average Ashworth Scale (AS) in Affected Lower Extremities From Baseline to Month 6 — -0.99; -0.43 units on a scale — p=0.0140
N/A N=9 Neurosciences-Intensive Care Unit Electrical Stimulation
Intensive Care (ICU) Myopathy
Primary: Duration of Intubation — 10.22 days
N/A N=8 Sensorimotor Imaging for Brain-Computer Interfaces
Functional Neuroimaging
Primary: Peak Activity Volume: Right D1 Attempt Movement Activity at S1 - SCI — 893.6 mm^3
N/A N=10 Hand Function for Tetraplegia
Spinal Cord Injury · Tetraplegia
Primary: Grasp Release Test - Test of Functional Ability to Pick up and Move Objects — 2; 5.5 Number of Completions
N/A N=84 Stroke Rehabilitation Using Brain-Computer Interface (BCI) Technology
Stroke
Primary: Action Research Arm Test Scores — 28.10; 27.76; 29.95; 30.18 score on a scale
N/A N=5 Prism Adaptation in Left Brain Stroke
Aphasia · Spatial Neglect · Stroke
Primary: Client Satisfaction Questionnaire — 32; 27 score on a scale
N/A N=46 Treatment of Chronic Stroke With AMES + EMG Biofeedback
Stroke · Plegia · Paresis
Primary: Box and Blocks Test — 0.0; 0.5 Number of blocks moved — p=<0.005
N/A N=27 A Clinical Demonstration of EEG Brain-computer Interface for ALS Patients
ALS (Amyotrophic Lateral Sclerosis)
Primary: BCI System Usage by the ALS Patient — 171 days
Phase 2 N=41 Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Chronic Aphasia
Aphasia
Primary: Change in WAB-AQ — 3.0; 2.8 score on a scale — p=<.05
N/A N=30 Rehabilitative Trial With tDCS in Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
Primary: Change in Muscle Strength From Baseline — 74.7; 74.7; 76.4; 74.5 units on a scale — p==0.001
N/A N=120 Treatment of Critical Illness Polyneuromyopathy
Acute Respiratory Failure
Primary: The Primary Outcome Variable for This Study Will be the Short Form of the Continuous Scale Physical Functional Performance Test (CS-PFP) Called the PFP-10 — 19.0; 20.9…
N/A N=13 Rehabilitation of the Upper Extremity With Enhanced Proprioceptive Feedback Following Incomplete Spinal Cord Injury
Spinal Cord Injury · Tetraplegia · Paresis
Primary: Grasp Release Test — 58.5; 72.0; 77.5 Objects moved — p=<0.025
N/A N=2 High Definition Neuromuscular Stimulation in Tetraplegia
Spinal Cord Injury at C4-C6 Level
Primary: Change in Voluntary Movement — 2; 0 Participants
N/A N=10 Robot-Assisted Therapy and Motor Learning: An Active Learning Program for Stroke
Stroke
Primary: Change From Baseline in Fugl-Meyer Assessment (FMA) - Upper Extremity Subtest — 11.0; 2.0; 8.5 score on a scale
N/A N=30 Eye-Control Trial: Wearable Eye-Tracking Device as Means of Communication
Acute Respiratory Failure Requiring Mechanical Ventilation
Primary: Number of Participants Who Succeeded in Operating the EyeControl Device — 11 Participants
N/A N=14 Targeted High-definition Transcranial Direct Current Stimulation (HD-tDCS) for Reducing Post-stroke Movement Impairments
Stroke
Primary: Fugl-Meyer Upper Extremity Assessment Part A — 4.13; 5.38; 0.88 score on a scale — p=<0.0001
N/A N=424 Powered Exoskeletons in Persons With SCI
Spinal Cord Injury
Primary: Improvement on the MCS in All Randomized Participants — 12; 14 Participants — p=0.798
N/A N=62 BCI-FES Therapy for Stroke Rehabilitation
Ischemic Stroke · Hemorrhagic Stroke
Primary: Gait Velocity — 0.38; 0.38; 0.46; 0.45 m/s