N/A N=104,219 Cardiovascular Disease Population Risk Tool
Cardiovascular Diseases
Primary: Major Cardiovascular Disease Event — 3182; 527 Cardiovascular disease event
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=103 Impact of INsulin Sensitivity on Cardiovascular Risk Markers During 10-20 Years of FOllow up
Diabetes Mellitus · Hypertension · Ischemic Heart Disease
Primary: Exploring Insulin Sensitivity After 10-20 Years of Follow-up — 7 mg/kg/min — p=<0.05
N/A N=13,381 Prioritized Clinical Decision Support (CDS) to Reduce Cardiovascular Risk
Hypertension · Hyperlipidemia · Diabetes
Primary: Predicted Annual Rate of Change in 10-year Risk of Fatal or Nonfatal Heart Attack or Stroke — -0.59; 1.66 annualized change in 10 year % cv risk — p=<0.05
N/A N=60 Low Fat Vegan or American Heart Association Diets & Cardiovascular Risk in Obese 9-18 y.o. With Elevated Cholesterol
Cardiovascular Disease · Hypercholesterolemia · Obesity
Primary: Change in Body Mass Index BMI Percentile — -1.12; -0.08; -1.29; -0.73 BMI percentile
Phase 4 N=22 EMERALD (Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders)
Lipid Disorder
Primary: Low-density Lipoprotein Cholesterol (LDL-C) Levels at Baseline and Day 30 — 110; 84.0 mg/dL
N/A N=69 The Effects of the Dietary Supplement CardioFlex Q10 on Reducing Cardiovascular Disease Risk Factors in Adults
Cardiovascular Diseases · Cardiovascular Abnormalities · Heart Attack
Primary: Change From Baseline of Total Cholesterol After 90 Days — -0.57; -1.09 mmol/L — p=0.042
N/A N=49 Reducing Cardiovascular Disease Risk in Perimenopausal Latinas
Cardiovascular Risk Factor · Health Behavior · Physical Activity
Primary: Change in Mean Systolic and Diastolic Blood Pressure (mm/Hg) From Baseline (Time 1) to Time 2 — -0.3; -2.4; 1.2; 2.2 mmHg
N/A N=6,009 Cardiovascular Risk Screening and Risk Reduction in Women Vets
Cardiovascular Diseases · Hypertension · Hyperlipidemias
Primary: New Participation in MOVE! (Among Women Aged 65 and Older) — 1.09 Odds Ratio — p=.003
N/A N=101 Cardiovascular Risk Assessment for Patients With Rheumatoid Arthritis Arthritis:
Rheumatoid Arthritis · Cardiovascular Diseases · Hyperlipidemias
Primary: Number of Subjects With Lipids Checked (Available Now Through National Laboratory Chain) or That Reported Having Their Lipids Checked by Their 1-week or 3-month Visit…
N/A N=77 A Personalized Dashboard to Educate Veterans at Risk of Stroke
Cardiovascular Disease · Stroke
Primary: Change in Percentage of Participants Who Initiate Conversation With Primary Care Provider About Vascular Risk — 11.1; -21.4 percentage of patients
Phase 2 N=216 Polypill For Prevention of Cardiovascular Disease
Cardiovascular Disease
Primary: Reduction of the Estimated 10-year Total Cardiovascular Risk Score — 11.5; 11.1 percent
N/A N=464 Tailored Communication to Reduce Cardiovascular Risk
Hypercholesterolemia · Coronary Artery Disease · Dyslipidemia
Primary: Comparative Outcomes: Intervention Group LDL Reduction Compared to Control Group LDL Reduction — 11.0; 11.1 % of patients with major LDL reduction — p=0.99
Phase 4 N=525 Reducing Total Cardiovascular Risk in an Urban Community
Cardiovascular Diseases · Heart Diseases · Coronary Disease
Primary: Low-density Lipoprotein Cholesterol — 100.1; 110.6 mg/dL — p=<0.001
N/A N=143 SomaSignal Tests on Medical Management and Change in Risk in Patients With Diabetes
Diabetes Mellitus, Type 2
Primary: Number of Participants With Type 2 Diabetes (T2D) Who Had Prescription Changes in Concordance With SSCVD Results — 45; 13; 8; 35 Participants
N/A N=45 Coronary Heart Disease as Measured by Coronary Calcium Score Among Individuals With Chronic Traumatic Spinal Cord Injury
Spinal Cord Injuries · Heart Diseases
Primary: Percent Agreement Between Coronary Calcium Score (CCS) and National Cholesterol Education Program (NCEP) Guidelines — 18 percent agreement
Phase 4 N=230 Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression
Atherosclerosis · Hypercholesterolemia
Primary: Change in Mean of Wall Volume of Internal Carotid Arteries — -3.52; -5.91 Other - mm^3 ( cubic millimeter )
N/A N=2,072 Cardiovascular Disease Risk Factors in Chinese American Immigrants
Hypertension · Cardiovascular Diseases · Diabetes Mellitus
Primary: Number of Participants With Hypertension — 532 participants
N/A N=70 Cardiovascular Disease (CVD) Risk and Prevention in Early Glucose Intolerance
Impaired Glucose Tolerance · Prediabetic State
Primary: AIM 1: Change in Flow Mediated Dilation (FMD) (%) — -0.0012; 0.018; 0.014; 0.0053 percentage of arterial dilation change — p=0.943
N/A N=2,039 Pathways to Cardiovascular Disease Prevention (DCRI Central and Statistical Coordinating Center)
HIV/AIDS · Cardiovascular Diseases
Primary: Number of Participants With Visit to a Cardiology Specialist From Cohort — 283 Participants
N/A N=10,347 Reducing Cardiovascular Risk in Adults With Serious Mental Illness
Chronic Disease · Mental Disorder · Health Behavior
Primary: Predicted Annual Rate of Change in 10 Year Risk of Fatal or Nonfatal Heart Attack or Stroke — 14.2; 20.8 percentage of annual rate of change
N/A N=143 Reducing Cardiovascular Disease Risk Factors in Rural Communities in North Carolina
Cardiovascular Diseases
Primary: Change in Weight — 0.41; 0.92 pounds
N/A N=862 The Healthcare Evaluation of Absolute Risk Testing Study
Cardiovascular Diseases
Primary: Feasibility: Count of Participants Who Were Successfully Returned a Result — 832 Participants
N/A N=97 Multifactorial Treatment of Cardiovascular Risk in Diabetic Patients: Identification of Treatment Non-Responders
Diabetes Mellitus, Type II
Primary: Change of Intima Media Thickness (IMT) — -0.023 mm — p=0.021
N/A N=269 Intervention Trial to Decrease Cardiovascular Risk in Persons With Serious Mental Illness
Cardiovascular Risk Factors · Serious Mental Illness
Primary: Global Framingham Risk Score — 11.5; 12.7; 9.9; 12.3 score on a scale
Phase 3 N=12,546 A Study to Assess the Efficacy and Safety of Enteric-Coated Acetylsalicylic Acid in Patients at Moderate Risk of Cardiovascular Disease
Moderate Risk of CVD
Primary: Time to the First Occurrence of the Composite Outcome of MI (Myocardial Infarction), Stroke, Cardiovascular Death, UA (Unstable Angina) or TIA (Transient Ischemic…
N/A N=9,559 Treatment of High and Very High riSk Dyslipidemic pAtients for the PreveNTion of CardiOvasculaR Events
Dyslipidemia · Cardiovascular Diseases · Hypercholesterolemia
Primary: Mean Low Density Lipid-Cholesterol (LDL-C) Levels in High and Very High Risk Cardiovascular Participants — 2.40; 1.99 mmol/L
N/A N=554 Communicating Multiple Disease Risks: A Translation of Risk Prediction Science
Healthy Volunteers
Primary: Change From Baseline to 90-day Follow-up in Self Reported Weekly Minutes of Exercise — 92.2; 37.5; 63.1; 60.0 minutes — p=0.0288
N/A N=104 Interventional Study to Decrease Cardiovascular Risk in Women in Primary Health Care in South Croatia
Cardiovascular Risk Factor
Primary: Ten Year Risk of Cardiovascular Disease (CVD) — 2.9 percentage of risk
N/A N=66 Study of the Long-term Effects of Exercise on Heath Indicators in Older People
Hypertension With Complications and Secondary Hypertension · Overweight and Obesity · Lipid Metabolism Disorders
Primary: Cardiovascular Disease Risk Factors — 3; 4; 5; 7 participants
Phase 2 N=8 Healthy Heart Habits
Acute Coronary Syndrome · Depression
Primary: Acceptability Measured by the Client Satisfaction Questionnaire — 30.57 score on a scale