N/A N=15 ICG Fluorescence Imaging in Lower Extremity Amputation Patients
Trauma Injury
Primary: Total Bone Blood Flow (TBBF)-Post Osteotomy — 4.9 mL/min/100g
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=35 Comparison of Non-Surgical Treatment Options for Chronic Exertional Compartment Syndrome (CECS)
Chronic Exertional Compartment Syndrome
Primary: University of Wisconsin Running Injury and Recovery Index Score at Baseline — 10.86; 11.86; 12.14; 9.75 cumulative score on a 9-item scale
Phase 4 N=100 Efficacy of Tranexamic Acid in Foot and Ankle Surgeries
Foot and Ankle Surgeries · Bunion
Primary: Total Estimated Blood Loss — 40.41; 18.75 ml
N/A N=30 Investigating Outcomes of Lower Limb Trauma
Trauma
Primary: Functional Outcome (Consisting of Questionnaire Score, Hamlyn Mobility Score (HMS) Gait/Activities of Daily Living Parameters) — 19.7; 58.2 units on a scale
N/A N=15 Functional Movement Retraining After Hip Replacement
Arthroplasty, Replacement, Hip
Primary: Change in Hip Disability and Osteoarthritis Outcomes Score (HOOS) - Activities of Daily Living Scale — -6.00 units on a scale
N/A N=10 Functional Outcomes in Dysvascular Transfemoral Amputees
Transfemoral Amputation · Unilateral Traumatic Amputation of Leg at or Above Knee
Primary: Change in Community Physical Activity as Measured by GPS — 1749; 1625; 1257 Steps per day
Phase 4 N=20 MIDCAB (Mid-Calf Block) for Foot Surgery
Ankle Surgery · Foot Surgery
Primary: Block Duration — 18.2 hours
N/A N=148 A Longitudinal Outcomes Study of the Subchondroplasty® Procedure in the Foot/Ankle
Insufficiency Fractures · Stress Fracture · Stress Fracture, Ankle, Foot and Toes
Primary: Foot Function Index-Revised (FFI-R) Short Form Score at 24 Months — 42.8; 43.0; 39.6 Percentage scale
N/A N=407 Intermittent Pneumatic Compression in Surgical Patients at Extremely-high Risk for Venous Thromboembolism
Venous Thromboembolism · Venous Thrombosis
Primary: Number of Patients With Asymptomatic Venous Thrombosis of Lower Limbs as Detected by Duplex Ultrasound — 1; 34 Participants — p=<0.001
Phase 4 N=165 Total Hip Arthroplasty (THA) Lumbar Plexus Verses Periarticular
Total Hip Arthroplasty
Primary: Maximum Postoperative Pain Score — 3.0; 4.0; 3.0 units on a scale — p=0.033
Phase 3 N=121 Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPAREL Admixed With Bupivacaine HCl vs. Bupivacaine HCl Administered as Combined Sciatic and Saphenous Nerve Blocks for Postsurgical Analgesia in Subjects Undergoing Lower Extremity Surgeries
Lower Extremity Surgery · Bunion · Metatarsophalangeal Fushion
Primary: Magnitude of the Analgesic Effect (NRS Pain Intensity) (AUC) — 298.65; 358.10; 380.05 score on a scale*hours
Phase 4 N=30 Peripheral Nerve Blocks for Above-the-knee Amputations
Peripheral Vascular Diseases · Hyperglycaemia (Diabetic) · Hypertension
Primary: Peripheral Nerve Block Success as a Primary Anesthetic — 1 Participants
N/A N=53 Immediate Weight Bearing Versus Protected Weight Bearing in Supracondylar Distal Femur Fractures
Closed Supracondylar Fracture of Femur
Primary: Time to Distal Femur Fracture Healing by Radiographic Evidence — 1.75; 2.15 months
N/A N=116 Implementation of Telemedicine for Patient With Lower Extremity Wounds
Peripheral Arterial Disease · Peripheral Artery Disease · Peripheral Vascular Diseases
Primary: Specialty Consultation — 66 days
N/A N=40 Femoral/Sciatic Block for Knee Surgery
Knee Injuries
Primary: Analgesic Efficacy — 0; 0.1; 0.6; 3.0 units on a scale — p=<0.05
N/A N=50 Agility LP Ankle Arthroplasty Outcomes
Rheumatoid Arthritis of Ankle · Osteoarthritis of Ankle · Traumatic Arthritis of Ankle
Primary: Assessment of Functional Outcomes Following Agility LP Ankle Replacement — 37.67; 37.07 Degrees
N/A N=80 Surgical Treatment of Hip Fractures Under Peripheral Regional Anesthesia
Hip Fractures
Primary: Success Rate (Supplemental Medication) — 22; 20; 3 Participants
N/A N=799 Study of SilverHawk®/TurboHawk® in Lower Extremity Vessels (DEFINITIVE™ LE)
Peripheral Arterial Disease · Claudication · Critical Limb Ischemia
Primary: Primary Patency Rate (in Patients Treated for Claudication RCC 1-3) — 81.6 percentage of lesions by Kaplan Meier
N/A N=23 Skeletal Muscle Atrophy and Dysfunction Following Total Knee Arthroplasty
Knee Osteoarthristis
Primary: Cross-sectional Area (CSA) of Muscle Fibers — 2680; 2377; 2028; 1882 micron squared
N/A N=48 Evaluating the Safety and Efficacy of Fractionated Carbon Dioxide Therapy in Postoperative Lower Extremity Wound Healing
Leg Ulcer
Primary: Number of Participants With Completely Healed Lower Extremity Wounds — 20; 18 Participants
N/A N=18 Evidence Based Amputee Rehabilitation (EBAR) Program
Amputation Stumps · Diabetes Mellitus
Primary: Amputee Mobility Predictor — 36.4; 35.3; 41.7; 35.6 Points
N/A N=272 Evaluation of Closed Incision Negative Pressure Dressing (PREVENA) to Prevent Lower Extremity Amputation Wound Complications
Amputation · Amputation; Postoperative, Sequelae · Wound Dehiscence
Primary: Overall Rate of Wound Complications — 26; 31 Participants
N/A N=95 Pelvis RCT: Impact of Surgery on Pain in Lateral Compression Type Pelvic Fractures
LC Pelvic Fracture
Primary: Posttreatment Pain — 5.3; 6.2; 4.2; 5.6 scores on a scale
N/A N=52 Lower Extremity Muscle and Function in the Elderly: Study 2
Mobility Limitation
Primary: Leg Extensor Muscle Power — 32.9; 41.6 Watts
Phase 4 N=49 Pilot Study Evaluating Alterations in Thrombogenicity and Platelet Reactivity Following Lower Extremity Arthroplasty
Primary Total Hip and Knee Arthroplasty
Primary: Blood Loss — 6; 1 participants
N/A N=50 Forensic-medical Aspects of Lower Limb Prosthetics: An Observational Study
Amputation
Primary: Questionnaire: Trinity Amputation Prosthesis Experience Scale (TAPES) — 57; 8; 40 units on a scale
N/A N=26 Improving Function After Knee Arthroplasty With Weight-Bearing Biofeedback
Arthropathy of Knee Joint
Primary: Weight-bearing Ratio During Five Times Sit-to-Stand Test (FTSST) — 0.77; 0.8 ratio — p==0.329
N/A N=80 Saphenous Nerve Block for Foot and Ankle Surgery
Saphenous Nerve Block
Primary: Block Success — 18; 22 participants — p=0.25
N/A N=168 The STEPS - Totalis™ Trial
Lumbar Spinal Stenosis
Primary: Percentage of Subjects With Clinically Significant Improvement in Outcomes — 56.3; 56.0 percentage of subjects
N/A N=80 A Physical Therapy Program Versus Surgery for Femoroacetabular Impingement: Randomized Clinical Trial
Femoroacetabular Impingement
Primary: Hip Outcome Score - ADL Subscale at 24 Months — 69.3; 73.1 score on a scale