30 closest matches · ranked by relevance
Dyspareunia · Vaginal Dryness
Primary: Female Sexual Function Index (FSFI) Score Compared to Baseline — 4.14; 5.95 score on a scale
Refractive Error
Primary: Average Coefficient of Friction of Worn Lenses at 16 Hours — 0.0602; 0.0576; 0.0578 unitless
Dry Eye Syndrome
Primary: Change From Baseline in Foreign Body Sensation, Burning/Stinging, Itching, Pain, Stick Feeling, Blurred Vision, Photophobia and Total Ocular Tolerability Score (VAS)…
Pelvic Floor Disorders
Primary: Pain During the Pelvic Floor Examination — 0.4; 0.9; 1.3; 3.6 units on Wong Baker pain scale
Ocular Discomfort
Primary: Changes From Baseline (Day 1 Pre-dose) in Ocular Tolerability Using a Visual Analogue Scale (VAS) — -22.8; -30.1; -20.9; -20.9 mm — p=0.3474
Dry Eye Syndrome · Tear Film Insufficiency
Primary: Change From Baseline (V2) in Frequency and Severity of Dry Eye Symptoms (SANDE) Questionnaire Scores at Day 28±4 (End of Treatment) — -11.9; -16.6; -25.0; -26.5 mm
Erythema · Edema
Primary: Number of Subjects With Observed Local Erythema Based on the 5 Point Scoring Scale — 0 Participants
Refractive Error
Primary: Average Coefficient of Friction (CF) at 16 Hours Compared to Unworn — 0.0394; 0.0396 unitless
Erythema · Edema
Primary: Number of Participants With Adverse Events as a Measure of Safety and Tolerability — 0 participants
Erythema · Edema
Primary: Number of Subjects With Observed Local Erythema Based on 5 Point Scale — 0 Participants
Dry Eye
Primary: Drop Comfort Upon Instillation — 1.7; 1.3 Units on a scale
Constipation
Primary: Change of Mucus and Mucin Secretion in Patients With Chronic Constipation and in Controls. — 260; 133; 229; 161 mg/hour
Dry Eye
Primary: Drop Comfort Upon Instillation — 1.1; 1.4 Units on a scale
Dry Eye
Primary: Percentage of Eyes With Graded Slit Lamp Findings Greater Than Grade 2. — 1; 0 eyes
Erythema · Edema
Primary: Number of Participants With Observed Local Erythema — 0 participants
Examination, Gynecological · Examination, Pelvic · Examination, Vaginal
Primary: Patient Discomfort During Speculum Insertion as Measured by a Visual Analog Scale. — 1.41; 2.15 score on a scale
Dry Eye
Primary: Tear Lipid Layer Thickness — 0.72; -7.58; 2.06; 1.41 nm
Erythema · Edema
Primary: Number of Patients That Showed Sensitization Reaction to the Test Material at Challenge — 0 Participants
Dry Eye Disease
Primary: Change From Baseline in Impact of Dry Eye on Everyday Life - Symptom Bother (IDEEL-SB) Questionnaire Score at Day 30 — -16.95 score on a scale — p=<.0001
Dry Eye Syndromes
Primary: Mean Frequency of Eye Drop Use Over 1 Week — 1.76; 1.66 Use per day
Dry Eye Syndromes
Primary: Change in Tear Lipid Layer Thickness — 4.8; 8.8 nm
Dry Eye
Primary: Time at Best Corrected Visual Acuity — 7.75; 6.42; 6.46; 5.51 seconds
Refractive Error
Primary: Mean Pre-lens Tear Lipid Layer Thickness After 2 Hours of Lens Wear on Day 1 — 61.2; 61.5 ICU
Coitus
Primary: Number of Participants Showing Change From Baseline in Irritation Scores — 0; 0 Participants
Dry Eye
Primary: Drop Comfort — 0.7; 1.05; 1.84; 1.1 units on a scale
Myopia · Astigmatism · Refractive Error
Primary: Mean Ex-Vivo Total Lipid Uptake Per Lens — 7.198; 35.879 micrograms
Erythema · Edema
Primary: Number of Participants With Observed Local Erythema — 0 participants
Inadequate Lubrication
Primary: Number of Participants With Physical Irritation Scores — 61; 61; 1; 0 Participants
Visual Acuity
Primary: Visual Acuity (logMAR) at 3 Minutes Post Instillation — 0.09; 0.08 LogMAR
Lubricating Agents
Primary: Number of Subjects With Irritation Score of "0" at Baseline and One Week — 35; 35; 35; 35 Participants