N/A N=158 Central Nervous System Amplification in Lumbar Failed Back Surgery Syndrome
Chronic Pain
Primary: Clinical Pain Severity - 50% Reduction Responders vs Nonresponders — -83; 0 percentage of change
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=27 Spinal Cord Stimulation in Patients With Post-Laminectomy Syndrome in Testing Phase
Laminectomy · Post-laminectomy Syndrome · Spinal Cord Syndrome
Primary: Comparing Visual Analogue Scale (VAS) — 9.3; 8.6; 5.7; 4.9 score on a scale — p=0.112
N/A N=120 Effectiveness of Percutaneous Lumbar Epidural Adhesiolysis and Neurolysis on Low Back Pain
Low Back Pain
Primary: Numeric Pain Rating Score — 7.9; 8.1; 4.9; 3.4 units on a scale — p=<0.001
N/A N=196 Efficacy of Acupuncture for Lumbar Spinal Stenosis
Lumbar Spinal Stenosis · Intermittent Claudication
Primary: The Change in Modified Roland-Morris Disability Questionnaire (RMDQ) Score From Baseline — -4.3; -3.0 score on a scale
N/A N=86 Pregabalin for the Treatment of Pain After Posterior Spinal Fusions
Lumbar Spinal Fusions
Primary: Patient Controlled Analgesia (PCA) Hydromorphone Usage — 44; 39 mL
Phase 4 N=32 GRASSP: Gralise® for Spine Surgery Pain
Post-laminectomy Pain Syndrome
Primary: Mean Change in Numeric Rating Scale (NRS) — -0.56; -0.54 units on a scale
N/A N=41 Study of PEMF (Pulsed Electromagnetic Field) Therapy in the Treatment of Persistent Post-Operative Pain Following Lumbar Surgery
Lumbar Surgery
Primary: Percent Change From Baseline in Pain Scores — -25.6; -40.2; -18.6 Percent Difference
Phase 4 N=29 Lumbar Stenosis Outcomes Research (LUSTOR)
Lumbar Spinal Stenosis
Primary: Time to First Symptoms of Moderate Pain — 2.52; 3.06 minutes
N/A N=92 Epidural Neuroplasty for the Treatment of Herniated Lumbar Disk
Herniated Lumbar Disc
Primary: Pain Assessed by Visual Analogue Scale — 5.63; 5.92 units on a scale
N/A N=248 Postoperative Management for Degenerative Spinal Conditions
Spinal Degenerative Disorder
Primary: Oswestry Disability Index (ODI) — 43.6; 45.46; 31.31; 31.19 units on a scale
N/A N=10 Postoperative Telehealth Mindfulness Intervention After Spine Surgery
Chronic Low-back Pain · Postsurgical Pain · Opioid Use
Primary: Feasibility - Study Retention — 3 Participants
Phase 4 N=304 Spinal Cord Stimulation for Low Back Pain
Chronic Pain
Primary: Effectiveness of SCS Stimulation in Reducing Back Pain Associated With Failed Back Surgery Syndrome After 12 Months of Use.
N/A N=59 Benefit of Lumbar Bracing for Chronic Low Back Pain Due to Degenerative Disc Disease
Degenerative Disc Disease · Lumbar Spondylosis · Low Back Pain
Primary: Pain Diary — 6.71; 5 units on a scale
Phase 4 N=83 Lumbar Plexus Block for Postoperative Pain Control After Hip Arthroscopy. A Randomized Controlled Trial
Postoperative Pain
Primary: Numeric Rating Scale (NRS) Pain at Rest (0-10) on Day of Surgery Prior to Discharge — 3.3; 4.2 units on a scale
N/A N=46 Vertos Mild - Post Market Patient Outcomes
Lumbar Spinal Stenosis
Primary: Pain as Measured by Visual Analog Scale (VAS). — 2.17 units on a scale — p=<0.0001
Phase 4 N=46 Lumbar Plexus vs Quadratus Lumborum Block in Post-operative Pain Following Total Hip Replacement
Hip Osteoarthritis
Primary: Pain at Rest After Surgery — 3.4; 3.6 score on a scale — p=.770
N/A N=10 Pain and Sensation After Regional Anesthesia - Pilot Study
Anesthesia, Conduction · Osteoarthritis, Hip
Primary: Patient Pain Score With Activity — 1.4 units on a scale
N/A N=48 Additional Gluteal Control Training for Low Back Pain With Functional Leg Length Inequality
Low Back Pain, Recurrent
Primary: Leg Length Inequality — 0.3; 0.58 centemeter
N/A N=100 Sagittal Plane Shear Index for Planning Lumbar Stenosis Surgery
Lumbar Spinal Stenosis · Spondylolisthesis
Primary: Proportion of Surgical Plans Recorded Prior to the SPSI Report That Are Altered After Integration of SPSI Into the Surgical Planning — 47; 22; 6 Surgical plans
N/A N=10 The Vertos MILD™ Preliminary Patient Evaluation Study
Lumbar Spinal Stenosis
Primary: Changes in Back Pain as Measured by a 10-point Visual Analog Scale (VAS). — 3.3 units on a scale
Phase 3 N=401 Corticosteroid Lumbar Epidural Analgesia for Radiculopathy
Lumbosacral Radicular Pain
Primary: Mean Change From Baseline (Day 1) to Week 4 in the Mean Numeric Pain Rating Scale (NPRS) Average Pain Score in the Affected Leg — -2.34; -1.16 Change in score on a scale…
N/A N=165 Long Term Outcomes of Lumbar Epidural Steroid Injections for Spinal Stenosis
Lumbar Spinal Stenosis
Primary: Utilization of ESI — 3.6; 3.3 number of ESI between 18-24 months
N/A N=178 Lumbar Degenerative Disc Disease Treated With Anterior Tension Band System (ATB) With ALIF/FRA Spacer
Lumbar Degenerative Disc Disease
Primary: Number of Subjects With Successful Radiographic Fusion — 90 Participants
Phase 2 N=149 Efficacy and Safety of ETX-018810 in Subjects With Lumbosacral Radicular Pain
Lumbosacral Radiculopathy
Primary: Change From Baseline to Week 4 in the Weekly Average of the Daily Pain Score as Derived From the Subject's Responses on the Pain Intensity Numerical Rating Scale…
Phase 4 N=146 Herniectomy Versus Herniectomy With a Spinal Stabilization System for the Treatment of Complex Disc Disease
Sciatica · Back Pain
Primary: To Demonstrate a Statistically Significant Difference in the Relief of Back Pain Between Both Treatment Groups. The Endpoint Will be the Difference Between Baseline and…
N/A N=54 Effect of Lumbar Bracing on Spinal Function
Low Back Pain
Primary: Oswestry Disability Index — .42; .83; 10.41; .42 score on a scale
N/A N=116 Compare Epidural vs. Lumbar Plexus Analgesia After Hip Arthroplasty
Arthropathy of Hip
Primary: Opiate Consumption — 64.8; 81.3 Opiate Consumption (IV MME)
N/A N=15 Treatment of Symptomatic Lumbar Internal Disc Disruption (IDD) With the Biostat® Disc Augmentation System: A Pilot Study
Low Back Pain
Primary: Numbers and Types of Adverse Events (Only Number of Events is Reported in This Section - See Adverse Events Section for Further Detail) — 17 Events
N/A N=178 Post-op Acetaminophen vs NSAID Use on Lumbar Spinal Fusion Outcomes
Lumbar Osteoarthritis · Spondylosis · Lumbar Disc Disease
Primary: Perioperative Opioid Use — 86.25; 306.6; 192.4; 88.95 oral morphine equivalents (OME) (mmg) — p=<0.001
N/A N=322 Post-Approval Clinical Trial Comparing the Long Term Safety and Effectiveness Coflex vs. Fusion to Treat Lumbar Spinal Stenosis
Spinal Stenosis
Primary: Number of Subjects With Improvement of at Least 15 Points in ODI — 41; 101 Participants