30 closest matches · ranked by relevance
Depressive Disorder · Anxiety
Primary: Double-blind Treatment Period: Change From Baseline in Hamilton Depression Rating Scale (HDRS17) Total Score at Week 6 (eITT Population) — -6.1; -6.5 Units on a scale…
Major Depressive Disorder With Anxious Distress
Primary: Change From Baseline in Hamilton Depression Rating Scale-17 (HDRS-17) Total Score at Week 6 — -8.8; -9.4 Units on a scale — p=0.2494
Major Depressive Disorder · Anxiety
Primary: Mean Change From Baseline in the Montgomery-Asberg Depression Rating Scale (MADRS) Total Score — -19.6 Units on a scale — p=<0.0001
Depressive Disorder · Depression · Depressive Disorder, Major
Primary: Change in the Montgomery-Asberg Depression — -10.4; -8.07 Units on a scale — p=0.0074
Depressive Disorder
Primary: Depression Treatment Outcome — 0.96; 1.33 units on a scale
Major Depressive Disorder
Primary: Percentage of Subjects With Treatment Emergent Adverse Events (TEAEs) — 66.7 percentage of subjects
Generalized Anxiety Disorder
Primary: Change From Baseline in the Hospital Anxiety and Depression Scale (HADS) Anxiety Subscale Score at Endpoint — 12.76; 13.56; -6.38; -5.29 Units on a scale — p=0.006
Anxious Major Depressive Disorder
Primary: Hamilton Rating Scale for Depression (HAM-D) Total Score. — 14.249; 16.307 Units on a scale
Major Depressive Disorder
Primary: MADRS Score - Overall Change From Baseline — 13.7; 8.8 score on a scale — p=<.001
Major Depressive Disorder With Mixed Features
Primary: Mean Change From Baseline to the 6-week Study Endpoint in Montgomery-Asberg Depression Rating Scale (MADRS) Total Scores — -20.5; -13.0 units on a scale — p=<0.0001
Generalized Anxiety Disorder (GAD)
Primary: Change From Baseline in Hamilton Anxiety Rating Scale (HAM-A) Total Score at Visit 7 (Day 42) — -9.01; -8.93 Score on scale
Adjustment Disorder With Anxious Mood
Primary: Hamilton Anxiety Scale (HAM-A) Score — -12.5; -12.6 score on a scale — p=0.9338
Anxiety · Anxiety Disorders · Anxiety Neuroses
Primary: Least Square Mean Change From Randomization to Week 8 in Hamilton Rating Scale for Anxiety (HAM-A) Total Score — -10.74; -9.61 units on scale
Depression · Generalized Anxiety Disorder · Panic Disorder
Primary: Change in Mental Health-related Quality of Life From Baseline to 24 Weeks — 8.87; 8.39 units on a scale — p=0.002
Autism Spectrum Disorders
Primary: Mean 10-Week Change in Pediatric Anxiety Rating Scale 5-Item Total Score, Double-blind Phase — -4.9; -3.2 score on a scale
Social Anxiety Disorder
Primary: Change in the Liebowitz Social Anxiety Scale (LSAS) Total Score — 93.4; 92.1; 55.0; 63.4 Scores on a scale
Bipolar Disorder · Panic Disorder · Generalized Anxiety Disorder
Primary: Clinician Global Improvement Scale (CGI-21) — 7.8; 3.4 units on a scale
Depression · Anxiety
Primary: Number of Participants Meeting Depression Remission Criteria — 10; 15 participants
Generalized Anxiety Disorder · Panic Disorder
Primary: Cumulative Percent of Participants Showing a Response in the Symptoms of Anxiety (Decrease in Total Hamilton Anxiety (HAM-A) -Score of >=50%) in the Intent-to-treat…
Major Depressive Disorder
Primary: Mean Change From Baseline (Day 1) to Day 56 in Montgomery-Asberg Depression Rating Scale (MADRS) Total Score. — -17.5 score on a scale
Separation Anxiety Disorder
Primary: Clinical Global Impression-Improvement Scale — 7; 4 Participants — p=.064
Major Depressive Disorder
Primary: Change From Baseline in Hamilton Depression Rating Scale (HAMD-17) Total Score at Weeks 8 — -9.0; -7.4 Scores on a scale — p=0.121
Alcohol Dependence · Major Depression · Social Anxiety Disorder
Primary: Percent Days Drinking — 34.9; 31.9 percentage of days drinking — p=0.64
Depression · Major Depressive Disorder
Primary: Change in MADRS Total Score From Baseline to Week 6 — 15.91; 12.04 score on a scale — p=0.002
Depression · Dysthymic Disorder
Primary: Change in Hamilton Rating Scale for Depression (HAM-D, 24-item) From 0 Weeks to 12 Weeks. — 8 units on a scale — p=<0.001
Depressive Disorder, Major · Anhedonia
Primary: Change From Baseline to Day 43 in the Montgomery-Asberg Depression Rating Scale (MADRS) Total Score — -11.4; -12.3 Units on a scale — p==0.467
Anxiety Disorder
Primary: Hamilton Anxiety Scale (HAM-A) Score at Study Endpoint. — 16.27; 15.82; 13.64; 15.55 units on a scale — p=<0.05
Alcohol Dependence · Anxiety Disorder
Primary: Treatment Adherence — 15 Participants
Major Depressive Disorder
Primary: Total Discontinuation - Emergent Signs and Symptoms (DESS) Score Over the First 2 Weeks of the Double-blind Phase — 4.1; 4.8; 5.3 scores on a scale
Alcohol-Related Disorders · Anxiety Disorders
Primary: Clinical Global Impression Scale-I (CGI-I) — 3.65; 3.81; 3.86; 4.05 units on a scale