N/A N=130 Maternal Role in Oral Feed Establishment in Preterm Neonates
Preterm Birth · Tube Feeding · Swallowing Disorder
Primary: Transition Time to Full Oral Feeding — 10; 9 days
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=54 Behavioral Change in the Mother-Infant Dyad: Preventing Postpartum Depression
Postpartum Depression
Primary: Hamilton Rating Scales of Depression — 12.09; 17.17 units on a scale — p=.01
N/A N=32 Neurobiological Bases of Paternal Nurturance
Healthy
Primary: Mean Percent Signal Change in Ventral Tegmental Area (VTA) — 0.54; 0.27 Percent signal change
N/A N=74 Intranasal Oxytocin and Maternal Neglect
Maternal Behavior
Primary: Differences in Brain Activation (Blood Oxygen Level Dependent [BOLD] Signal) of Dopamine Reward Regions and Prefrontal Cortex After Intranasal Oxytocin Administration in…
N/A N=38 Attachment and Biobehavioral Catch-up and Depression Treatment
Maternal Depression · Child Behavior Problem
Primary: Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Depression Score — 6.70; 6.98 units on a scale — p=.85
N/A N=175 PREPP: Preventing Postpartum Depression
Postpartum Depression (PPD)
Primary: Score on the Edinburgh Postnatal Depression Scale (EPDS) — 5.04; 4.36; 4.43; 4.04 score on a scale
N/A N=36 Neurophysiology of Postpartum Depression in an Experimental Model of Pregnancy and Parturition
Postpartum Depression
Primary: Blood-oxygen-level-dependent (BOLD) Response During Functional Magnetic Resonance Imaging (fMRI) z Statistic — 2.3; 2.0; 2.1; 1.7 z score — p=.27
N/A N=368 Reducing Maternal Depression and Promoting Infant Social-Emotional Health & Development
Maternal Depression and Parent Practices, Postpartum · Infant Development
Primary: PHQ9 — 11.94; 10.31; 5.61; 5.33 score on a scale — p=0.503
Phase 2 N=100 Brief Intervention in At-Risk First-time Mothers
Substance Use
Primary: Alcohol Use — 1.37; 0.92 units on a scale
N/A N=70 Using Mental Imagination to Prevent Excessive Gestational Weight Gain in Overweight and Obese Pregnant Women
Obesity · Weight Gain, Maternal
Primary: Percent Change in Body Weight — 10.9; 9.6 percentage change
N/A N=281 Maternal-Offspring Metabolics:Family Intervention Trial
Pregnancy · Weight Gain
Primary: Gestational Weight Gain (GWG) — 12; 10 kg — p=0.01
N/A N=426 A Randomized Controlled Trial to Improve Mother-Infant Synchrony Among Women With Childhood Adversity
Parent-Child Relations · Maternal Behavior · Infant Behavior
Primary: Mother-Infant Synchrony, Gaze and Affect — 113.89; 106.72; 28.2; 16.1 seconds of synchrony
Phase 1 N=21 Brain Dynamics of Oxytocin
Brain Dynamics in Healthy Adults
Primary: Number of Benevolent Rounds — 6.8; 6.8 number of rounds
N/A N=252 Collaborative Perinatal Mental Health and Parenting Support in Primary Care
Parenting · Mother-child Relations
Primary: Change in Parent Sensitivity in Teaching — 36.73; 35.32 score on a scale — p=.026
N/A N=47 Stage I Randomized Trial of Mentalization-Based Therapy for Substance Using Mothers of Infants and Toddlers
Maternal Substance Use · Child Abuse and Neglect
Primary: Maternal Capacity for Reflective Functioning (Assessed With the Parent Development Interview) — 3.59; 3.08; 3.54; 3.47 units on a scale
N/A N=80 Mother-Infant Psychoanalysis Project of Stockholm
Mother-infant Relational Disturbances
Primary: The Parent-Infant Relationship Global Assessment Scale (PIR-GAS; ZERO-TO-THREE, 2005) — 83.53; 76.67 Scores on a scale — p=.006
N/A N=42 Attachment and Biobehavioral Catch-up for Depression
Depressive Symptoms · Anxiety Symptoms
Primary: Change From Baseline in Internalizing Subscale Score of the Child Behavior Checklist (CBCL) at Week 10 (Value at Baseline Minus Value at Post Intervention (Week 10))…
N/A N=152 Sleep Disruption in New Mothers: An Intervention Trial
Pregnancy · Postpartum Period · Sleep Disturbance
Primary: Maternal Sleep Quantity (Objective) — 6.1; 6.6 hours
N/A N=93 Preschooler Emotion Regulation in the Context of Maternal Borderline Personality Disorder
Borderline Personality Disorder · Emotional Problem
Primary: Maternal Emotion Dysregulation — 82.35; 91.8 score on a scale — p=.002
Phase 3 N=311 Physical Activity in Women With Infants
Physical Activity
Primary: Minutes of Moderate or Vigorous Physical Activity Per Week After 12-months — 246; 156 minutes per week moderate-to-vigorous PA
N/A N=42 Mommy-Baby Treatment for Perinatal Depression
Depressive Disorder, Major · Postpartum Depression
Primary: Change in Edinburgh Depression Scale From Baseline — 17.81; 17.9; 12.04; 11.41 units on a scale
N/A N=630 Maternal Adversity, Vulnerability and Neurodevelopment
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse) · Infant Development · Infant Behavior
Primary: Child's Cognitive Development Measured Using the Bayley Scales of Infant Development II. — 524; 508; 458; 422 Participants
N/A N=180 Early Initiation of Milk Expression in Mothers of Very Low Birth Weight Infants
Breast Milk Expression
Primary: Pumped Milk Volume Day 1 — 3; 4; 5 mL — p=0.015
N/A N=55 Listening Visits for Emotionally Distressed Mothers of Hospitalized Newborns
Nurse Delivered Counseling · Emotional Distress
Primary: Mean IDAS-GD Score at 4 Weeks (End of Treatment) and 8 Weeks (Follow up) — 46.12; 51.10; 40.11; 42.39 score on a scale — p=<0.05
N/A N=81 A Smartphone-Assisted Brief Behavioral Intervention for Pregnant Women With Depression
Perinatal Depression
Primary: Change in Maternal Prenatal Depression at Baseline, Midpoint, and Posttreatment (8 Weeks) — 17.3; 16.8; 12.5; 12.1 score on EPDS — p=0.757
Phase 4 N=41 Sequencing Treatments for Mothers With ADHD and Their At - Risk Children
Attention Deficit Hyperactivity Disorder
Primary: Child Behavioral Functioning — 4.78; 4.56; 4.44; 4.67 units on a scale
N/A N=74 Prenatal Breast Pump Education of Mothers and Their Support Person
Preterm Birth · Breast Feeding
Primary: Onset of Lactogenesis Stage II Through Volume Attainment — 84.8; 81 hours — p=0.985
N/A N=70 Impact of Skin to Skin Contact on Maternal Satisfaction, Pain Scores, and Narcotic Usage After Cesarean Delivery
Skin to Skin Contact in Cesarean Deliveries
Primary: Maternal Evoked Pain Scores — 43.55 units on a scale
N/A N=280 PRenatal Video-Based Education and PostPARtum Effects
Breastfeeding
Primary: Breastfeeding Exclusivity — 67; 84 Participants — p=.1200
Phase 2 N=109 Inhaled Oxytocin and HPA Axis Reactivity
Depression, Postpartum · Anxiety Disorders · Stress, Psychological
Primary: Mean Cortisol (CRT) During Trier Social Stress Test (TSST) — 19.17; 16.87; 15.71; 13.89 pg/mL — p=0.37