N/A N=205 Depression Attention for Women Now (The DAWN Study)
Depressive Disorder
Primary: Depression Treatment Outcome — 0.96; 1.33 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=73 Drug Therapy to Treat Minor Depression
Depression
Primary: Efficacy Assessed Using the Inventory of Depressive Symptomatology - Clinician Rated (IDS-C) — -11.47; -9.35; -10.49 units on a scale
Phase 2 N=97 Assessing Symptomatic Clinical Episodes in Depression
Major Depressive Disorder
Primary: MADRS Score - Overall Change From Baseline — 13.7; 8.8 score on a scale — p=<.001
Phase 2 N=102 A Study to Evaluate SAGE-217 in Participants With Moderate to Severe Major Depressive Disorder
Major Depression
Primary: Percentage of Participants With Treatment-emergent Adverse Events (TEAEs) - Part A — 92.3 percentage of participants
N/A N=31 Efficacy of Adjunctive Exercise for the Behavioral Treatment of Major Depression
Major Depressive Disorder
Primary: Montgomery-Asberg Depression Rating Scale (MADRS) — 11.2; 16.0 score on a scale
N/A N=141 Treatment of Depressed Chronic Obstructive Pulmonary Disease Patients
Pulmonary Disease, Chronic Obstructive · Major Depression
Primary: Composite Antidepressant Score Scale (CAD) — 29; 25; 9; 20 Participants
Phase 3 N=126 Role of Magnesium Supplementation in the Treatment of Depression
Depression
Primary: Patient Health Questionnaire-9 — -4.28; -0.09 score on a scale
N/A N=30 Treatments for Improving Mood in Depressed Teens-3
Depression
Primary: Acceptability — 11; 13 Participants
N/A N=100 Supportive and Supportive-Expressive Treatment for Depression
Major Depressive Disorder
Primary: Hamilton Rating Scale for Depression (HRSD) — 12.32; 12.06; 20.20; 20.08 units on a scale — p=.016
N/A N=11 Treatments for Improving Mood in Depressed Teens-2
Depression
Primary: Acceptability — 9 Participants
Phase 4 N=53 Effects of Treatment on Decision-making in Major Depression
Major Depressive Disorder · Healthy Controls
Primary: Money Earned — 23.2; 25.0; 20.5; 21.9 US Dollars
N/A N=100 Treatment of Depression in Acute Coronary Syndrome (ACS) Patients
Depression
Primary: Depression and Well-being Improvements After Cognitive-Behavioral Therapy and Well-Being Therapy as Assessed by Changes in Clinical Interview for Depression, Compared to…
N/A N=64 Virtual Reality Compared to Screen Based Engagement on Mood
Virtual Reality
Primary: Change in Positive Affect and Negative Affect From Baseline to After a 2 Minute Mood Induction — 3.7; 4.63; 1.97; 1.56 units on a scale
N/A N=38 Treating Major Depression With Yoga: A Prospective, Randomized Controlled Pilot Trial
Depression, Unipolar
Primary: Intent-to-Treat Analysis of Adjusted Mean Beck Depression Inventory-II Scores Over Intervention Period — 20.98; 19.92; 15.15; 13.06 points on a scale — p=0.034
N/A N=84 Spirituality Teaching Program for Depressed Adults
Major Depression
Primary: Hamilton Depression Rating Scale - Depression Severity — 20.4; 20.3; 11.9; 18.0 units on a scale
N/A N=9 European Deep Brain Stimulation (DBS) Depression Study
Depressive Disorder, Major
Primary: Mean Percent Change From Baseline in MADRS Score — -7.7; -7.4; -8.8; -6.2 percentage change from baseline
N/A N=48 Standardized Versus Tailored Implementation of Measurement Based Care for Depression
Depression
Primary: Patient Health Questionnaire — 18.04; 16.77; 12.15; 13.09 score on a scale
N/A N=2,452 Testing Scalable, Single-Session Interventions for Adolescent Depression in the Context of COVID-19
Depression
Primary: Change in Adolescent Depressive Symptom Severity — 14.31; 14.15; 14.22; 12.57 Score on a scale
Phase 2 N=7 Treatment of Young Adults With Comorbid AUD/MDD: A Pilot Medication Trial
Major Depressive Disorder · Alcohol Use Disorder
Primary: Drinks Per Drinking Day — 2.8; 2.0 Drinks per drinking day
N/A N=94 Stress and the Sympathetic Nervous System in Adults With Depression
Major Depressive Disorder
Primary: Percent of Days Participants Report Stressors — 36; 40 percent of days
N/A N=168 Motivational Interviews for Depression in Primary Care
Major Depression
Primary: Depression Remission — 4; 15 participants
Phase 1 N=5 Antidepressant Effects of NR2B in Major Depression
Major Depression
Primary: Montgomery-Asberg Depression Rating Scale (MADRS) — 22.519; 23.633 Score on a scale — p=.272
N/A N=132 Novel Neural Circuit Biomarkers of Major Depression Response to CCBT
Depression · Major Depressive Disorder · Depressive Disorder
Primary: Resting State Functional Connectivity: MDD vs Controls — .51; .65; .54 Z normalized correlation
Phase 3 N=190 Magnetic Brain Stimulation for the Treatment of Adult Depression
Depression
Primary: Depression Remission, as Measured by the Hamilton Rating Scale for Depression — 13; 5; 43; 12 number of remitted patients
Phase 3 N=108 Omega 3 for Treatment of Depression in Patients With Heart Failure
Depression
Primary: Endpoint Hamilton Depression Rating Scale (HAMD) Scores Adjusted for Age, Sex, Treatment Site, and Baseline HAMD Scores. — 15.1; 15.7; 14.9 units on a scale — p=0.74
N/A N=52 Feasibility Study to Test Clinical Efficacy of Low Energy AC Magnetic Field to Treat Major Depression
Major Depressive Disorder (MDD)
Primary: Percent Change in Hamilton Depression Rating Scale (HAMD-17) at Baseline and the End of Week 4 of Treatment. — -53.8; -53.1; -24.2 % change in HAM-D score
Phase 2 N=296 Establishing Moderators and Biosignatures of Antidepressant Response for Clinical Care for Depression
Depression
Primary: Hamilton Rating Scale for Depression — 11.06; 12.52 units on a scale
N/A N=48 Group Depression Treatment for Autistic Youth
Autism Spectrum Disorder · Depression · Suicidal Ideation
Primary: Change in Severity of Adolescent Depressive Symptoms, Self-report — 8.14 T-score
N/A N=45 CBT Enhanced With Social Cognitive Training
Depression
Primary: Faux Pas Recognition Test — 0.901; 0.854 score on a scale — p=< 0.05
N/A N=55 Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression
Major Depressive Disorder
Primary: Percentage Change in Prefrontal Cortex (PFC) Cerebral Blood Flow (CBF) During High-Irradiance t-PBM — 1.12 Percent change in raw frontal BOLD