Phase 2 N=115 Dental Pain Study of Analgesics in Patients Undergoing Molar Removal
Dental Pain
Primary: Sum Pain Intensity Difference Scores — -2.4292; -68.0778; -68.3533; -93.3645 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=235 Efficacy Of PF-05089771 In Treating Postoperative Dental Pain
Postoperative Dental Pain
Primary: Total Pain Relief From 0 to 6 Hours (TOTPAR[6]) — 6.94; 6.21; 7.00; 14.43 units on a scale
N/A N=655 A Real-World Evidence Study to Evaluate Oral Health Related Quality of Life Using an Anti-Sensitivity Toothpaste
Dentin Sensitivity
Primary: Mean Score of DHEQ Section 1 - Impact on Everyday Life (Question [Q]1-3) at Baseline (Day 0) — 5.90; 6.17; 5.20 score on a scale
Phase 4 N=49 Compare Anti-inflammatory Dentifrices
Gingivitis
Primary: Gingival Index (GI) — 1.04; 1.01 units on a scale — p=<0.05
Phase 3 N=321 Nefopam/Paracetamol Fixed Dose Combination in Acute Pain After Impacted Third Molar Extraction
Acute Pain
Primary: Ranked Endpoints : 1. Sum of Pain Intensity Differences at 6 Hours (SPID0-6h) — 8955.4; 8458.0; 5290.7 score on a scale — p=0.0031
N/A N=32 Effects of Photobiomodulation on Postoperative Pain After Primary Endodontic Therapy in Molars With Symptomatic Apical Periodontitis
Postoperative Pain
Primary: Pain as Assessed by the Visual Analog Scale — 0; .33 score on a scale
Phase 3 N=118 The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Mean Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Week 8 — -0.9; -0.5 Score on a scale — p=<0.0001
N/A N=104 Research on Oral Tolerability and Product Application/Response of Two Oxalate Products for Dental Patients With Risk of Dentinal Hypersensitivity
Dentinal Hypersensitivity
Primary: How Satisfied Were Participants With Treatment? — 0; 1; 2; 2 Participants
Phase 3 N=113 Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Day 14 — -1.20; -0.37 Score on a scale — p=<0.0001
N/A N=204 The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity (DH)
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score on Day 3 — -1.37; -0.45 score on a scale — p=<.0001
Early Phase 1 N=46 Pain Management in Teeth With Reversible Pulpitis
Reversible Pulpitis · Ibuprofen
Primary: Change in Pain Intensity From Baseline (Pre-Operative) to Immediately During the Procedure (Day 0), Measured by the Visual Analogue Scale (VAS) — 5.05; 0.64 score on a…
Phase 2 N=269 A Dental Pain Study to Test the Effectiveness of a New Pain Reliever Medicine
Pain
Primary: Analgesic Efficacy From 0 to 6 Hours After the Dose Using the Time-weighted Sum of Pain Intensity Difference (SPID 0-6) — 4.37; 20.75; 8.95; 20.56 units on a scale…
Phase 4 N=401 Post-operative Dental Pain Study Comparing Two Different Dosage of Analgesic Efficacy
Post-surgical Dental Pain
Primary: Sum of Pain Relief and Pain Intensity Differences From 0 to 6 Hours (SPRID 6 Hours) — 16.08; 12.42; 4.63 Score on a scale — p=0.0009
Phase 2 N=21 Occlusal Adjustment as Treatment for Chronic Orofacial Pain
Temporomandibular Joint Disorders · Orofacial Pain
Primary: Visual Analogic Scale for Pain Intensity (0-10) — 6.52; 4.8; .81; 2.05 units on a scale
Phase 2 N=611 Analgesic Effect of Different Combinations of Dexketoprofen Trometamol With Tramadol Hydrochloride in a Model of Moderate to Severe Pain
Pain
Primary: Percentage of Patients Achieving at Least 50 % of the Theoretical Maximum Total Pain Relief Score at 6 Hours Post-dosing. — 36.7; 59.7; 55.6; 72.1 percentage of patients
Phase 2 N=120 Efficacy, Tolerability, Safety, and Pharmacokinetic Study of DFN-15
Acute Pain
Primary: Summed Pain Intensity Difference Over the First Six Hours — -420.2; -1101.0; -1771.7; -1463.5 units on a scale — p=<0.0001
Phase 3 N=626 The Efficacy of a Toothpaste to Reduce Sensitivity
Dentin Hypersensitivity
Primary: Hypersensitivity Tactile(Yeaple Probe) — 19.81; 13.94 units on a scale — p=0.05
Early Phase 1 N=114 Pre-operative Analgesics for Postoperative Pain Relief After Dental Treatment
Pain, Postoperative · Analgesia
Primary: Postoperative Pain, as Measured by Wong-Baker Facial Rating Pain Scale ,After Routine Dental Treatment — 20; 20; 7; 11 Participants
Phase 3 N=374 A Dental Pain Study Comparing The Analgesic Efficacy Of Ibuprofen/Caffeine
Pain
Primary: Time Weighted Sum of Pain Relief Rating (PRR) and Pain Intensity Difference (PID) Scores From 0 to 8 Hours Post-dose (SPRID 0-8): Ibuprofen + Caffeine Versus Ibuprofen…
N/A N=79 Clinical Efficacy of a Toothpaste on Hypersensitivity Reduction
Hypersensitivity
Primary: Tooth Hypersensitity to Touch Stimuli (Tactile) — 10.83; 10.63 Units on a scale — p=0.05
N/A N=221 A Study to Investigate Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Pain Derived From Exposed Dentine in Response to Chemical, Thermal, Tactile, or Osmotic Stimuli.
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score at Week 8 (Treatment 1 and 2 Versus [vs.] Placebo) — 2.51; 2.53; 2.54; -1.57 Score on scale — p=<0.0001
N/A N=78 Multicentre Observational Study on the Wound Pain Relief Properties of ORTODERMINA®
Wound Healing Disorder
Primary: Change of Pain Relief From Baseline to the End of Treatment Using the 5-point Visual Rating Scale (VRS) — 3; 23; 28; 20 Participants
N/A N=87 Occurrence of Post-op Pain Following Gentlewave
Root Canal Infection · Endodontic Disease · Endodontic Inflammation
Primary: Level of Post-operative Pain (2018-2019) — 23.2; 11.56 score on VAS scale
N/A N=230 The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score on Day 3 — -0.96; -0.77 Score on a scale — p=0.1575
Phase 4 N=300 Post-operative Dental Pain Study Comparing Analgesic Efficacy
Post-surgical Dental Pain
Primary: Sum of Pain Relief and Pain Intensity Differences From 0 to 6 Hours (SPRID 6 Hours) — 10.60; 5.87; 3.35 Units on a scale — p=0.0004
Phase 4 N=654 Tramadol Hydrochloride and Dexketoprofen Trometamol for the Oral Treatment of Moderate to Severe Acute Pain Following Removal of Impacted Lower Third Molar
Acute Pain
Primary: TOTPAR6 (Total Pain Relief Over 6 Hours Post-dose) — 13.0; 9.2; 1.9 5-point Verbal Rating Scale
Phase 2 N=403 Study of Long-Acting Acetaminophen in Postoperative Dental Pain
Dental Pain
Primary: Time Weighted Sum of Pain Intensity Difference (PID) Over 10 Hours (SPID 0-10) — 5.745; 30.986 units on a scale — p=<0.001
N/A N=36 Effects of an Oxalate Containing Product on Dentinal Hypersensitivity With Dental Prophylaxis
Dentin Sensitivity
Primary: Change From Baseline Air Challenge — -0.412; -0.132 Units on a scale
N/A N=263 A Study to Measure the Efficacy of a Toothpaste on Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Thermo-evaporative (Schiff Air Blast) Stimuli — 2.188; 2.246; 1.268; 1.811 score on a scale — p=<0.001
Phase 2 N=110 A Study of Acetaminophen for Post Surgical Dental Pain
Pain, Postoperative · Dental Pain
Primary: Sum of Pain Intensity Difference From 0 to 24 Hours (SPID24) Based on the 11 Point Numeric Pain Rating Scale — -96.80; -100.69; -74.96 score on a scale — p=0.0258