Phase 4 N=393 Acetaminophen (APAP) +/- Oxycodone
Musculoskeletal Pain
Primary: Change in Pain Assessment — 2.9; 4.0 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=60 A Comparison of Proprietary Formulations of Oral Ketamine + Aspirin and Oral Ketamine Alone for Musculoskeletal Pain
Pain
Primary: Change in Pain Score at 60 Minutes — 2.18; 4.01 units on a scale
N/A N=7 Percutaneous Peripheral Nerve Stimulation (Neuromodulation) for Postoperative Analgesia
Postoperative Pain
Primary: Change From Baseline of Surgical Site Pain Level (NRS) at Rest [Percentage of Baseline Pain] — 64; 100; 55; 69 percentage of baseline
Phase 4 N=200 Assessment and Prevention of Acute Post-herniotomy Pain
Hernia
Primary: Analgesic Efficacy — 26.5; 32.3 percentage of patients with NRS≥4
N/A N=1,602 A Depression and Opioid Pragmatic Trial in Pharmacogenetics (Acute Pain Trial)
Acute Pain
Primary: 10 Day Silverman Integrated Analgesic Assessment (SIA) Score — 1.4; -1.4 score on a scale — p=0.7957
N/A N=78 Multicentre Observational Study on the Wound Pain Relief Properties of ORTODERMINA®
Wound Healing Disorder
Primary: Change of Pain Relief From Baseline to the End of Treatment Using the 5-point Visual Rating Scale (VRS) — 3; 23; 28; 20 Participants
N/A N=90 The Impact of IV Acetaminophen on Pain After Appendectomy for Perforated Appendicitis
Perforated Appendicitis
Primary: Time Until PCA Discontinued After the Operation — 76.4; 86.7 hours
N/A N=20 Usability of a Multimodal External Neuromodulatory Device to Relieve Acute Low Back Pain
Low Back Pain · Low Back Sprain · Low Back Pain, Recurrent
Primary: Change in Pain: Visual Analog Scale (VAS) — 2.1 units on a scale (centimeters)
N/A N=122 Percutaneous Auricular Neuromodulation for Postoperative Analgesia
Postoperative Pain, Acute
Primary: AVERAGE Pain Measured With the Numeric Rating Scale First 5 Postoperative Days — 1; 3 units on a scale
N/A N=16 Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain
Phantom Limb Pain · Postoperative Pain · Neuroma
Primary: Average Phantom Limb Pain (PLP) Score — 4.1; 3.1; 2.2; 3.0 score on a scale
Phase 2 N=250 Analgesic Effect of IV Acetaminophen in Tonsillectomies
Adenotonsillitis · Tonsillitis
Primary: FLACC Pain Score Greater Than or Equal to 4 — 58; 69 Participants
Phase 4 N=67 Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries
Pain · Postpartum Depression
Primary: Perineal Pain in Postpartum Patients 1 Week After Obstetric Anal Sphincter Injuries. — 3.5; 2.7; 2.4 score on a scale
Phase 4 N=66 IV Acetaminophen for Acute Post Operative Pain in C-Section Patients
Post-operative Pain
Primary: Opioid Requirements in Cesarean Section (C-section) Patient Population — 44; 48; 58; 57 mg
N/A N=156 Acute Pain Genomic Study
Osteoarthritis · Postoperative Pain
Primary: NRS-Pain With Movement on POD 2 — 2.83 units on a scale
N/A N=165 Acupuncture in the Emergency Department for Pain Management
Acupuncture · Pain Management · Emergency Department
Primary: Successful Recruitment of Participants Into the Study. — 26.1; 27.7; 16.3; 49.1 Percentage of participants enrolled
N/A N=49 Ear Acupuncture for Pain Associated With Ambulatory Arthroscopic Knee Surgery
Pain
Primary: Number of Participants With a Decrease in Pain Level — 18; 16 Participants
Phase 3 N=407 Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After Abdominoplasty
Acute Pain
Primary: Number of Patients Who Respond to Study Medication at the 24-hr Numeric Pain Rating Scale (NPRS) Assessment Compared to Placebo. — 47; 61; 56; 37 Participants
N/A N=10 Virtual Reality for Pain in Acute Orthopedic Injuries
Injuries · Injury Arm · Injury;Sports
Primary: Credibility and Expectancy Questionnaire (CEQ)- Credibility Subscale — 8 Participants
N/A N=153 Acupuncture for Pain Management During Uterine Aspiration
Pain Acute · Acupuncture
Primary: Visual Analog Scale for Pain (VAS Pain) Score - Acupuncture Versus Routine Care — 39.5; 71.0 score on a scale
Phase 3 N=120 Ibuprofen With or Without Acetaminophen for Low Back Pain
Low Back Pain
Primary: Change in Functional Impairment as Measured by the Roland Morris Disability Questionnaire — 11.1; 11.9 units on a scale
N/A N=69 High Pain Intervention in Cesarean Sections
Other Chronic Postoperative Pain
Primary: Severity of Acute Pain — 46; 31 mm — p=0.05
N/A N=575 Persistent Pain After CS Delivery
Persistent Pain After Delivery
Primary: Persistent Pain-PERCEIVED STRESS Scores Stratified by the Rate of Recovery — 11.4; 12.9; 15.4 units on a scale — p=<0.01
Phase 4 N=119 Intravenous Acetaminophen for Non-Narcotic Postoperative Pain Management Following Knee Arthroscopy
Pain, Postoperative
Primary: Postoperative Pain Levels — 1.3160; 2.1362 score on a scale
N/A N=402 Preventing Persistent Post-Surgical Pain and Dysfunction
Pain · Function · Anxiety
Primary: Pain Intensity — 4.1; 3.9; 3.9; 3.4 units on a scale
Phase 4 N=204 IV Acetaminophen for Postoperative Pain After Pelvic Organ Prolapse Repair
Pelvic Organ Prolapse
Primary: Change From Baseline in Postoperative Pain — 20.5; 29.2; 20.7; 20.1 units on a scale — p=<0.05
N/A N=70 Auricular Vagus Nerve Stimulation for Chronic Pain
Low Back Pain
Primary: Low Back Pain Intensity — 1.24; 1.73 units on a scale
N/A N=40 Acupuncture ACL (Anterior Cruciate Ligament)
ACL · ACL Injury · Anterior Cruciate Ligament Injury
Primary: Bang Blinding Index (BI) — 0.2; 0.11 score on a scale
Phase 4 N=65 Postoperative Pain Control in Septum and Sinus Surgery
Post-operative Pain · Sinus Surgery
Primary: Number of Doses of Opiate (Narcotic) Pain Medication — 1.0; 1.5 number of doses
Phase 4 N=416 Comparative Efficacy of 4 Oral Analgesics
Pain
Primary: Between Group Difference in Change in Numerical Rating Scale (NRS) Pain Scores — 4.4; 3.5; 3.9; 4.3 units on a scale
N/A N=60 Adjunct VR Pain Management in Acute Brain Injury
Traumatic Brain Injury · Headaches Posttraumatic · Trauma
Primary: Change in Pain Score — -0.92; -0.16; -1.24 score on a scale