N/A N=122 Percutaneous Auricular Neuromodulation for Postoperative Analgesia
Postoperative Pain, Acute
Primary: AVERAGE Pain Measured With the Numeric Rating Scale First 5 Postoperative Days — 1; 3 units on a scale
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Phase 4 N=180 IV Acetaminophen for Post-Operative Pain Management in Enhanced Recovery After Surgery (ERAS) Population
Abdominal Wall Hernia · Pancreatic Diseases · Bowel Disease
Primary: Postoperative Pain Intensity — 33; 42 Participants
N/A N=7 Percutaneous Peripheral Nerve Stimulation (Neuromodulation) for Postoperative Analgesia
Postoperative Pain
Primary: Change From Baseline of Surgical Site Pain Level (NRS) at Rest [Percentage of Baseline Pain] — 64; 100; 55; 69 percentage of baseline
Phase 4 N=66 IV Acetaminophen for Acute Post Operative Pain in C-Section Patients
Post-operative Pain
Primary: Opioid Requirements in Cesarean Section (C-section) Patient Population — 44; 48; 58; 57 mg
N/A N=16 Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain
Phantom Limb Pain · Postoperative Pain · Neuroma
Primary: Average Phantom Limb Pain (PLP) Score — 4.1; 3.1; 2.2; 3.0 score on a scale
Phase 4 N=204 IV Acetaminophen for Postoperative Pain After Pelvic Organ Prolapse Repair
Pelvic Organ Prolapse
Primary: Change From Baseline in Postoperative Pain — 20.5; 29.2; 20.7; 20.1 units on a scale — p=<0.05
Phase 4 N=200 Assessment and Prevention of Acute Post-herniotomy Pain
Hernia
Primary: Analgesic Efficacy — 26.5; 32.3 percentage of patients with NRS≥4
N/A N=63 NSS-2 BRIDGE Device in Post-Operative Pain Management
Acute Pain · Surgery · Abdominal Cancer
Primary: Opioid Consumption — 24; 38; 24; 27 oral morphine mg equivalents (OME)
N/A N=86 Pregabalin for the Treatment of Pain After Posterior Spinal Fusions
Lumbar Spinal Fusions
Primary: Patient Controlled Analgesia (PCA) Hydromorphone Usage — 44; 39 mL
Phase 3 N=234 OxyNorm Capsules in Post-Operative Pain Study
Postoperative Pain
Primary: Visual Analogue Scale (VAS) in Resting Stage at 6hour (6hour±20 Minutes After Administration of First Dose) — 46.21; 45.48; 20.21; 19.94 units on a scale
N/A N=5 NSS-Bridge Device for Post-Cesarean Delivery Pain
Acute Pain · Cesarean Delivery
Primary: Opioid Consumption — 31 milligrams of oxycodone
Phase 2 N=120 Local Anesthetics on Postsurgical Analgesia Following Posterior Colporrhaphy
Postoperative Pain
Primary: Change in Vaginal Pain Scores Using the Defense and Veterans Pain Rating Scale (Visual Analog Scale) Between Bupivacaine Alone Versus Exparel® Following Posterior…
N/A N=148 Intravenous Versus Oral Acetaminophen for Postoperative Pain Control After Cesarean Delivery
Pain, Postoperative
Primary: Cumulative Postoperative Opiate Consumption — 2.9; 3.8; 5.7 mg
Phase 4 N=343 PAIN - Postoperative Analgesia INvestigation
Postoperative Pain
Primary: Postoperative Pain as Assessed by a Numeric Pain Scale (NPS) — 5.05; 5.02 units on a scale — p=0.934
N/A N=50 Auriculotherapy for Surgical Pain
Acute Pain · Surgery · Shoulder Pain
Primary: Opioid Consumption Following Rotator Cuff Surgery — 31; 25; 25; 21 oral morphine mg equivalents (OME) — p=0.1771
Phase 4 N=56 B&O for TLH Post-operative Pain and Nausea
Hysterectomy · Pain, Postoperative
Primary: Post-operative Pain: VAS — 4.1; 4.8 score on a scale — p=0.17
Phase 4 N=119 Intravenous Acetaminophen for Non-Narcotic Postoperative Pain Management Following Knee Arthroscopy
Pain, Postoperative
Primary: Postoperative Pain Levels — 1.3160; 2.1362 score on a scale
N/A N=69 High Pain Intervention in Cesarean Sections
Other Chronic Postoperative Pain
Primary: Severity of Acute Pain — 46; 31 mm — p=0.05
Phase 4 N=65 Postoperative Pain Control in Septum and Sinus Surgery
Post-operative Pain · Sinus Surgery
Primary: Number of Doses of Opiate (Narcotic) Pain Medication — 1.0; 1.5 number of doses
N/A N=53 Auricular Percutaneous Electrical Nerve Field Stimulation for Postoperative Pain Control in Adults
Pain, Postoperative
Primary: Total Narcotic Consumption During Hospital Stay — 90.79; 90.30 Oral Morphine Equivalents per day (OME) — p=0.97
Phase 4 N=180 Minimal Opioid Use After Total Hip Replacement (THR)
Osteoarthritis, Hip
Primary: Opioid Use — 30; 22.5; 15 Oral Morphine Equivalent (mg)
Phase 4 N=183 IV Acetaminophen for Postoperative Pain Analgesia After Laparoscopic Hysterectomy
Pain
Primary: Postoperative Pain — 3.55; 3.11 units on a visual analog scale
N/A N=90 The Impact of IV Acetaminophen on Pain After Appendectomy for Perforated Appendicitis
Perforated Appendicitis
Primary: Time Until PCA Discontinued After the Operation — 76.4; 86.7 hours
Phase 4 N=41 Acetaminophen's Efficacy For Post-operative Pain
Tonsillitis · Airway Obstruction · Difficulty Swallowing
Primary: Total Pain Medication — 1.7; 2.2 mg
Phase 4 N=67 Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries
Pain · Postpartum Depression
Primary: Perineal Pain in Postpartum Patients 1 Week After Obstetric Anal Sphincter Injuries. — 3.5; 2.7; 2.4 score on a scale
Phase 4 N=68 IV Acetaminophen as an Adjunct Analgesic in Cardiac Surgery
Acute Pain · Hyperalgesia
Primary: 24 Hour Postoperative Opioid Consumption — 62.3; 45.6 mg — p=0.024
Phase 4 N=40 Improving Post-Operative Pain and Recovery in Gynecologic Surgery
Postoperative Pain · Opioid Use · Acetaminophen
Primary: Postoperative Pain: Standardized Pain Scale — 2.82; 3.18 score on a scale — p=.378
N/A N=160 Patient-Driven Analgesic Protocol Selection for Post-Cesarean Pain Management
Postoperative Pain
Primary: Opioid Consumption in the 0-48 Hour Study Periods. — 10; 5; 10; 5 milligram morphine equivalents (MMEQ)
Phase 3 N=204 Study to Evaluate Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy
Hemorrhoids
Primary: Area Under the Curve (AUC) of the Numeric Rating Scale at Rest (NRS-R) Pain Intensity Scores — 359; 396 Units on a scale*hours
Phase 4 N=120 Multimodal Pain Management for Cesarean Delivery
Pain
Primary: Total Opioid Intake in Morphine Milligram Equivalents in the First 48 Hours After Cesarean Delivery (CD) — 42; 49.5 morphine milligram equivalents