N/A N=57 Insulin-sensitive Obesity: Lessons From Longitudinal Data
Insulin Sensitivity/Resistance · Obesity
Primary: Insulin Sensitivity — 0.0105; -0.0076; 0.0041 micro mol/min/Kg/mU/L/year
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=102 Metformin in Overweight Type 2 Diabetes Mellitus
Obesity · Type 2 Diabetes Mellitus
Primary: Change in Weight From Baseline at 12 Months or More — -8.37 Kg — p=<0.05
N/A N=281 Maternal-Offspring Metabolics:Family Intervention Trial
Pregnancy · Weight Gain
Primary: Gestational Weight Gain (GWG) — 12; 10 kg — p=0.01
N/A N=82 Physical Exercise Influence Among Overweight and Obese Pregnant Women
Obesity · Overweight
Primary: Gestational Weight Gain — 10.3; 11.5 kg — p=<0.05
N/A N=271 Weight Discrimination and Poor Cardiovascular Health
Obesity
Primary: Negative Affect — 1.43; 1.29 score on a scale — p=.007
Phase 3 N=302 Enhancing Fitness in Older Pre-diabetic Veterans
Impaired Glucose Tolerance · Obesity · Diabetes
Primary: Fasting Insulin — 10.26; 10.39 uIU/ml
Phase 2 N=181 Effect of LIK066 on Body Weight in Patients With Elevated Body Mass Index
Elevated Body Mass Index
Primary: Part 1: Percent Change in Body Weight From Baseline to Week 12 — -5.51; 0.19; -6.55; 0.29 percent change — p=<0.001
N/A N=684 INtervention Study In overweiGHT Patients With COPD
Pulmonary Disease, Chronic Obstructive · Obesity · Weight Loss
Primary: Six Minute Walk Test — 1071.0; 1005.9 feet — p=.02
Phase 4 N=18 Effect of Weight and/or Obesity on Ethambutol Drug Concentrations
Obesity · Tuberculosis
Primary: Total Clearance of Ethambutol — 80.8 L/h
N/A N=360 Lifestyle and Pregnancy: The Clinical Effect of Lifestyle Intervention During Pregnancy in Obese Women
Maternal Obesity · Gestational Weight Gain · Obstetric Complications
Primary: Cesarean Section
N/A N=330 Daily Habits & Consumer Preferences Study
Obesity
Primary: Hyperpalatable Food Intake — 325.95; 262.51 kilocalories
N/A N=33 Young Adult Eating Habits
Eating Behavior · Eating Habit
Primary: Change in Brain Response From Baseline to 2-weeks Post High UPF or 2 Weeks no UPF Diet — 0.02; 0.13 arbitrary units
N/A N=118 Weight Management for Improved Pregnancy Outcomes
Obesity · Pregnancy
Primary: Maternal Weight Change — 1.2; -2.6 kg
N/A N=5,392 Impact of Body Weight on the Immediate Health of the Pediatric Population
Childhood Obesity
Primary: Diagnosis of Infectious Disease — 900; 1067 Participants — p=.026
Phase 2 N=387 A Study to Test Whether Different Doses of BI 456906 Help People With Overweight or Obesity to Lose Weight
Obesity
Primary: Percentage Change in Body Weight From Baseline to Week 46 — -6.19; -12.51; -13.22; -14.94 Percentage change — p=<0.0001
N/A N=105 Behavioral Weight Loss and Stigma Reduction
Obesity
Primary: Percent Weight Change at Week 72 — -7.16; -5.19 percent weight change — p=0.14
N/A N=46 Targeting Body Image Among Women of Higher Body Weight
Obesity · Overweight · Body Image
Primary: EDE-Q Weight and Shape Concern — 3; 6; 0; 3 Participants
N/A N=30 Estrogen Sensitivity and Ovulatory Dysfunction in Obesity
Obesity · Infertility
Primary: Luteinizing Hormone Pulse Amplitude — 2.73; 1.12 IU/L
Phase 4 N=32 Oral Contraceptives and Body Mass Index
Body Weight · Contraceptive Usage
Primary: LNG Steady State at Baseline and Then Post-randomization — 3.82; 3.13; 3.01; 3.58 ng/mL
N/A N=18 The Effects of Chiropractic in a Population With High Central Adiposity
Abdominal Obesity
Primary: Proportion of Potential Participants Who Are Eligible. — 0.95 Proportion
N/A N=76 Pediatric Quality of Life Among Population With Body Mass Index (BMI) Greater Than or Equal to 85%
Pediatric Obesity
Primary: Change in Child Self-report Health Related Quality of Life Scores After Intervention: Total, Physical and Psychosocial (Presented in This Order) — 7.8; -0.9; 9.1; -0.3…
N/A N=50 Guided Self-help for Families With an Overweight Child
Obesity
Primary: Child BMI — 23.3; 25.17 kg/m^2
N/A N=79 Evaluation of Ovarian Morphology and Function in Overweight Women During Weight Loss
Weight Loss · Anovulation · Amenorrhea
Primary: Change From Baseline Ovulatory/Menstrual Function — 12; 18 Participants
N/A N=20 A 6-month Observational Study on Combined Oral Contraceptives and Body Weight in Pre-Menopausal Women With Overweight or Obesity
Contraceptive Usage · Overweight or Obesity · Body Weight Changes
Primary: Number of Premenopausal Women With Overweight/Obesity Who Initiated a COC vs. Continued NHC Use, Enrolled and Remained in This Study, and Completed Outcome Measures — 9…
N/A N=60 Dysregulation of FSH in Obesity: Functional and Statistical Analysis
Obesity · Fertility
Primary: Difference Between Peak Inhibin B — 100.8; 38.8 picograms/mL
Phase 3 N=50 Safety and Efficacy of Adjustable Gastric Band Operations for Patients With Body Mass Index (BMI) Between 30-40 kg/m2
Obesity
Primary: To Determine Percent of Excess Weight Loss (%EWL) After Laparoscopic Adjustable Gastric Banding Surgery — 51.74 percentage of excess weight loss
N/A N=54 Internet-Administered Smoking Cessation Treatment for Overweight and Obese Smokers
Smoking Cessation · Overweight · Obesity
Primary: Number of Participants With Verified Smoking Cessation (Abstinence) — 7; 5 participants
Phase 3 N=261 Obese Hypertension Study (0954-315)
Hypertension
Primary: Mean Change From Baseline in Trough Sitting Systolic Blood Pressure (SiSBP) at Week 8 — -12.1; -6.8 mm Hg
N/A N=277 Toddler Overweight Prevention Study Among Low-Income Families
Overweight · Obesity · Depression
Primary: Change of Body Mass Index (BMI) Z-score for Toddlers — 0.49; 0.50; 0.62; 0.52 z-score — p=0.555
Phase 3 N=130 A Primary Care Behavioral Approach for Addressing Childhood Overweight
Obesity
Primary: BMI Z-score(for Gender and Age)at 6-months — -0.129; 0.001 Z-score