Clinical Trial Search

Primary: Daily Evening Patient Reported Pain Intensity Scores — 0.14; 1.57 Units on a Scale — p=0.003

Primary: Change in Neuropathic Pain Score at 2 Months (Numeric Rating Scale 0-10) — 4.1; 4.6 units on a scale

Primary: Mean Neuropathic Pain Score at Visit 3 (Week 1) — 51.00; 50.70 Units on a Scale

Primary: Changes in Small Nerve Fiber Density by Assessment of a Skin Biopsy Comparing Baseline to Day 60 — .1; .1 nerve fibers / mm squared

Primary: Numeric Rating Scale (NRS) Pain Intensity — -0.83; -0.45 units on a scale — p=0.47

Primary: Change in Spontaneous Pain at 60-120 Minutes After Lidocaine Infusion Initiated (Assessed on 0-10 NRS) — 33; 51 percentage of pain change from baseline — p=0.03

Primary: Change From Baseline to End of Treatment (EOT) in Weekly Mean Pain Score on the Daily Pain Rating Scale (DPRS) — -3.8 scores on scale — p=< 0.0001

Primary: Baseline Mean Pain Score — 6.41; 6.54 units on a scale

Primary: Neuropathic Pain in Subjects With Peripheral Neuropathic Pain Conditions During the Double-blind Phase — 2.84; 3.62 score on scale — p=0.0018

Primary: Opioid Consumption Between the Treatment and the Control Groups (Morphine Equivalents) — 7.0; 6.7 morphine equivalents — p=<0.05

Primary: Gracely Pain Scale (GPS) — -2.51; -1.96; -2.38; -0.99 GPS pain score on a scale

Primary: Weekly Mean Pain Score at End of Treatment (Week 8) From Daily Pain Diary — 4.61; 5.23 score on a scale — p=0.010

Primary: Daily Pain Rating Scale (DPRS)- Mean Pain Score (ITT Population) — 4.63; 5.13 score on scale — p=0.049

Primary: Change From Baseline in Mean Peripheral Neuropathic Pain on a 0-10 Numerical Rating Scale (NRS) Score at the End of Treatment (15 Weeks) — -1.36; -0.84 units on a scale…

Primary: Change From Baseline In Average Pain Level At Month 3 Telephonic Interview — 6.7; -2.2 Units on a scale — p=<0.001

Primary: VAS After Treatment — 4.9; 5.6 Visual Analog Scale — p=.04

Primary: Change From Baseline in the Mean Daily Peripheral Neuropathic Pain on a 0-10 Numerical Rating Scale Score During the Last Seven Days of Treatment (End of Treatment)…

Primary: The International Spinal Cord Injury Pain Data Set (ISCIPBDS) (Version 2.0) - Change in Average Worst Neuropathic Pain Intensity — -0.5; -0.5 points

Primary: Change in Spontaneous Pain Intensity as a Function of Baseline MPT — -0.0179; -0.0172 Pearson correlation coefficient

Primary: Change From Baseline of Surgical Site Pain Level (NRS) at Rest [Percentage of Baseline Pain] — 64; 100; 55; 69 percentage of baseline

Primary: Change From Baseline in Weekly Mean 24-hour Average Pain Severity (APS) Score at 5 Weeks — -2.08; -2.22; -2.45; -2.42 units on a scale

Primary: Number of Participants With Peripheral Edema — 5; 9; 2; 0 Participants

Primary: Number Meeting Success Criterion — 10; 5; 0 participants meeting success criterion — p=>0.05

Primary: Absolute Change in Mean Pain Score, Using an 11 Point Numeric Pain Rating Scale (NPRS) — -0.87; -0.74 score on a scale — p=0.67

Primary: Change From Baseline in Average Pain Intensity as Measured by the Numeric Rating Scale (NRS) — -1.70; -1.81 score on a scale

Primary: Change in Pain Score — -0.6224; -1.005; -0.8102; -1.079 score on a scale

Primary: Brief Pain Inventory, Worst Pain — 8.9; 9.7 score on scale

Primary: Reduction in Spontaneous Pain Intensity After a Peripheral Nerve Block. — 6.5; 0.0 units on a scale

Primary: Change in Pain Relief With Visual Analog (VAS) Pain Scale — 3.586; 5.494; 4.041; 5.677 score on a scale

Primary: Voxel-wise Blood Oxygen Level Dependent (BOLD) Using Functional Magnetic Resonance Imaging (fMRI) of Brain Activation Signals Across the Whole Brain