30 closest matches · ranked by relevance
Patients With Moderate-to-severe COPD With Destroyed Lung by Tuberculosis
Primary: Trough Forced Expiratory Volume in One Second Change — 0.08; -0.06 Liters — p=<0.0001
HIV · Chronic Obstructive Pulmonary Disease (COPD) · Emphysema
Primary: Safety of Doxycycline, as Measured by the Number of Subjects With Any Treatment-related Adverse Events. — 3; 1 Participants
Healthy · Latent Tuberculosis Infection (LTBI)
Primary: Median Difference in CD4 Cell Response to Intrabronchial Instillation of Tuberculin Purified Protein Derivative (PPD) — 5.26; 0.725; 29.9; 2.92 % Antigen Specific T…
Emphysema
Primary: Count of Patients With Grade 3 or Higher Adverse Events. — 3 Participants
Tuberculosis · AIDS-related Complex
Primary: Sputum Conversion — 36; 60; 36 percentage of participants
COPD
Primary: Spirometry Measurement: Percentage of Predicted Forced Expiratory Volume in 1 Second (FEV1 %Pred) — 75.572; 100.837; 108.311; 111.849 percent of predicted FEV1 — p=<0.0001
Pulmonary Disease, Chronic Obstructive · Bronchitis, Chronic
Primary: Change From Baseline in Volume of Mucin Per Surface Area of Basal Lamina — 2.565; 1.180 micrometer^3/micrometer^2 — p=0.5305
Chronic Obstructive Pulmonary Disease (COPD)
Primary: Pre-dose FEV1 — 1.079; 1.009 Ratio — p=<.0001
Pulmonary Disease, Chronic Obstructive
Primary: Number of Hospital Admissions in Chronic Obstructive Pulmonary Disease (COPD) Patients — 665; 765 Hospitalizations — p=0.24
COPD
Primary: Time to All-cause Mortality or Re-hospitalization During the 180 Days Post-randomization. — 54; 55 Days to event — p=<0.1
Pulmonary Tuberculosis
Primary: Comparison of the Rate of Treatment Success at 18 Months (After Treatment Initiation) Between Arms B and C — 217; 121; 117; 5 Participants
Tuberculosis · Multi-Drug Resistant Tuberculosis
Primary: Changes in TB Lesion Sizes Using High Resolution Computed Tomography (HRCT). — 8.11; 10.08; 6.64; 7.24 reader score
COPD
Primary: Bronchodilator Response:Peak FEV1(L)(Forced Expiratory Volume in One Second)- — 1.74; 1.82 liters — p=0.027
Chronic Obstructive Pulmonary Disease
Primary: Safety Profile of Oral Cyclosporin A Immunotherapy in Advanced Stage Chronic Obstructive Pulmonary Disease Patients- Nephrotoxicity - Measured by Serum Creatinine…
Idiopathic Pulmonary Fibrosis
Primary: 6 Minute Walk Distance — -6.2; -15.3 meters
COPD
Primary: Forced Expiratory Volume in 1 Second (FEV1) Area Under the Curve (AUC) 0-24 — 0.192; 0.112; -0.072 Liters
COPD
Primary: FEV1 AUC0-24 on Day 29 — 0.166; -0.083 Liters
Obliterative Bronchiolitis
Primary: Per Cent Change of Forced Expiratory Volume in 1 Second (FEV1) After Bronchodilators — 14; 7 per cent positive change
Pulmonary Disease, Chronic Obstructive · Pulmonary Emphysema
Primary: Absolute Change From Baseline at Week 156 in Adjusted Lung Density (ALD) Based on Percentile Density at 15% (PD15) Adjusted for Lung Volume — -0.27; -3.15; -5.04; -4.74…
COPD Patients With Homogeneous Emphysema · Endoscopic Lung Volume Reduction With Endobronchial Valve
Primary: Percentage Change in Forced Expiratory Volume in 1 s (FEV1) (ITT Population) — 13.7; -3.2 percent change
Pulmonary Disease, Chronic Obstructive
Primary: Number of Participants Who Received COPD Prescription for Maintenance Treatment at Baseline — 735; 68; 554; 105 Participants
Chronic Obstructive Pulmonary Disease, COPD
Primary: Peak Forced Expiratory Volume in One Second (FEV1) Relative to Baseline — 1708.0; 1877.3; 1881.8; 1883.6 mL — p=<0.001
Pulmonary Disease, Chronic Obstructive
Primary: Age of the Chronic Obstructive Pulmonary Disease (COPD) Patients at the Time of COPD Diagnosis - US — 65.6; 64.4 Years
COPD
Primary: Change From Baseline in Trough FEV1 at Treatment Visit Day 7 Compared to Placebo. — -0.0282; -0.0156; 0.0540; 0.0806 liters — p=0.9730
Chronic Obstructive Pulmonary Disease · Emphysema · Chronic Bronchitis
Primary: Phagocytosis of H. Influenzae Concentration — 0.042; 0.042; 0.014; 0.06 relative fluorescence unit — p=0.05
MDR-TB
Primary: STREAM Stage 2 Primary Outcome Measure (the Proportion of Patients With a Favourable Outcome at Week 76) — 0; 133; 162; 122 Participants
Chronic Obstructive Pulmonary Disease
Primary: To Evaluate the Rate of Severe Exacerbations in COPD, Comparing COPD Patients Previously Treated According to the PRO-CT Protocol Versus COPD Patients Previously Treated…
Chronic Obstructive Pulmonary Disease · COPD
Primary: Forced Expiratory Volume in One Second (FEV1) at 1 h Post-inhalation — 1.676; 1.595 Liters — p=0.0017
Pulmonary Disease, Chronic Obstructive
Primary: Number of Participants With Any Adverse Events (AEs) and Serious AEs (SAEs) — 120; 27 Participants
COPD · COPD Exacerbation · COPD Exacerbation Acute
Primary: Change in St. George Respiratory Questionnaire (SGRQ) Scores — 39.02; 45.06 score on a scale