Clinical Trial Search

Primary: The Feasibility of Inpatient Bedside Neurocognitive Testing of Pediatric Patients With Minor Traumatic Brain Injury. — 120 participants

Primary: First 3-day Cumulative Intensive Care Unit (ICU) Traumatic Brain Injury (TBI) Guideline Adherence Rate, Overall — 81.7; 81.0; 83.7; 84.4 mean percentage of guideline…

Primary: Parent Outcome-Vanderbilt ADHD Parent Rating Scales (VADPRS) — 1.10; 1.47; .84; 1.14 units on a scale

Primary: Fraction of Time That Brain Oxygen Levels Are Below the Critical Threshold of 20 mm Hg . — 0.15; 0.44 Proportion

Primary: VR-based EF Assessment Task — 1.41; 1.53; 1.71; 1.82 Z-Score

Primary: Participation Assessment With Recombined Tools - Objective 17 (PART-O-17) — 1.30; 1.33 units on a scale — p=0.44

Primary: Level of Simulator Sickness [Feasibility and Safety] — 0.16; 0.03 score on a scale

Primary: Change in Quality of Life as Measured by the Short Form-36 (SF-36) — 47.97 score on a scale

Primary: Sensitivity: Percentage of MRIs Correctly Identifying Clinically Important Intracranial Injury (True Positives) — 70 Percentage of MRIs correctly identifying

Primary: Sleep Disturbances Scale for Children — 55; 69; 64; 73 T-score

Primary: Number of Participants With Improved Cerebral Perfusion — 8 Participants

Primary: PTSD Symptoms in Children 6 Weeks Post-injury — 12.6; 13.6 Units on a scale — p=.69

Primary: Number of Participants Who Reported 5 Themes — 6; 6; 6; 6 participants

Primary: Assess Parents' Knowledge Regarding Their Child's Risk for a Significant Brain Injury — 6.2; 5.26 Number of questions correct out of 10

Primary: Consumer Assessment of Healthcare Providers and Systems Child Hospital Survey Communication Subscale — 0.769; 0.775; 0.735; 0.747 score on a scale

Primary: Number of Participants Who Experienced Adverse Events — 0; 2 participants

Primary: Glasgow Outcome Scale Extended (GOSE) — 7; 5 Glasgow Outcome Scale Extended (GOSE)

Primary: Change in Executive Functioning as Assessed by the Trail Making Test — -9.2; 24.7 change in seconds — p=.323

Primary: Count of Children Who Have Persistent Post-concussive Symptoms (PCS) at One-month Follow-up. — 510; 291 Participants

Primary: Maximum Oxygen Uptake at Baseline. — 29.0 mL/kg/min

Primary: Percent Change in Trail Making Test Part B Time to Completion — -25.6 percent change in time

Primary: Functional Outcome 6 Months After Injury, as Measured by the Processing Speed Index — 82.5; 82.5 Processing speed index standardized scor

Primary: Post-traumatic Stress Symptoms (Child Post-traumatic Stress Disorder (PTSD) Scale) Through the First and Last Survey Administered Post-Baseline — 10.64; 8.53; 9.87; 8.17…

Primary: Number of Subjects Completing the Two Structured Outpatient Intervention Programs Resilience and Adjustment Intervention (RAI) vs. RAI With Follow-up Booster Sessions…

Primary: Pediatric Quality of Life Inventory (PedsQL) — 64.9; 60.2; 67.2 Quality of life units * months

Primary: Depression at Baseline — 27.5; 25.2 units on a scale

Primary: Assessing Severity of Symptoms Associated With Attention-deficit/Hyperactivity Disorder (ADHD) in Children When Using Vyvanse Versus Placebo by Administering the…

Primary: Computer Cognitive Test Scores - ImPACT Verbal Memory — 70.48; 74.21; 78.12; 75.36 units on a scale

Primary: Examiner Score — 0.617; 0.907; 0.865; 1.155 score on a scale

Primary: Responses From the TBI Clinical Reminder — 61; 88 percentage of participants