Clinical Trial Search

Primary: Percentage of Participants With Safety Adverse Events — 3.92 Percentage of Participants

Primary: Proportion of Participants With Improvement in Periorbital Wrinkles From Baseline — 10; 2; 8; 2 Participants

Primary: Local and Systemic Adverse Events — 100 percentage of participants

Primary: The Primary Objective of This Study is to Determine the Efficacy and Longevity of the Use of Restylane® and Perlane® in Combination for the Rejuvenation of the…

Primary: Graded Change in Dermatochalasis — .2679 units on a scale

Primary: Overall Improvement in Periorbital Wrinkles and Rhytids Around the Eyes — 47; 50 percentage of participants improved

Primary: Percentage of Subjects With a ≥1 Grade Improvement From Baseline in Infra-Orbital Area on the Allergan Infra-Orbital Rating Scale (AIRS) on the Right and Left Side — 99…

Primary: Posttreament Results of Chemical Peel if Botox A is Added as Pre-treatment — 1; 2 Units on a wrinkle severity scale — p=.002

Primary: Change From Baseline in Texture Score at Visit 4 (End-of-study Session) — 0.25; -4.75 score on a scale — p=0.075

Primary: Number of Participants Who Showed Improvement in Under Eye Swelling and Dark Circles Relative to Baseline Per Intervention — 0; 0 participants — p==1

Primary: Nasal Tip Projection — 0.601 ratio

Primary: Subject Satisfaction — 2.8 score on a scale

Primary: Treatment Difference in VAS (Perlane Side - Perlane-L Side) With Difference in VAS >= 10 mm — 95 Participants

Primary: Number of Participants With Effectiveness and Safety Success — 30; 41 participants

Primary: Volumetric Change in Infraorbital Treatment Baseline to Each Post-intervention Timepoint Day 14, Day 30, and Day 90 — -0.026; -0.065; -0.108 cc

Primary: Fitzpatrick Wrinkle Assessment — 1.0; 1.5; 1.1 units on a scale, change in Fitzpatrick

Primary: Change in Neck and Facial Wrinkles Using the Fitzpatrick Wrinkle Assessment — 74 percentage of participants

Primary: Number of Subjects With Naturalness of Expression in Motion (2D Video) — 30 Participants

Primary: Percentage of Subjects Achieving None or Mild on the Investigator's Assessment of the Severity of Crow's Feet Lines (CFL) at Maximum Smile Using the Facial Wrinkle…

Primary: Responder Rate Based on the Blinded Evaluator's Live Assessment of the Galderma Infraorbital Hollows Scale (GIHS) — 87.4; 17.7 Percentage of participants — p=<0.001

Primary: Responders Rate Using the Global Aesthetic Improvement Scale (GAIS) at Maximum Frown (Glabellar Lines) — 100 percentage of participants

Primary: Inter-rater Reliability of Assessment of Facial Lines Using the 4-Point Facial Wrinkle Scale (FWS-A) — 0.653; 0.637; 0.647; 0.654 Kappa statistics

Primary: Treatment Success — 89.08 % of participants

Primary: Change in Facial Wrinkles at 12 Weeks Post Final Treatment Compared to Baseline — -0.10 units on a scale

Primary: First Impressions — 46.756; 27.769; 46.391; 34.404 score on a scale

Primary: Percentage of Subjects With a ≥ 2-grade Improvement From Baseline on the Lateral Canthal Line Investigator and Subject Assessments at Maximum Smile at One Month. — 106…

Primary: Number of Responders on the Severity of Lateral Canthal Lines "at Maximum Smile". — 119; 6 Participants

Primary: Percentage of Participants With at Least a 1-point Improvement Change From Baseline on the Allergan Infraorbital Hollows Scale (AIHS) Based on Evaluating Investigator's…

Primary: Change From Baseline in Perioral Rhytids Severity Rating Scale (PR-SRS) Score Rated by the Blinded Live Evaluator (BLE) at Week 8 After Last Treatment. — 121; 4; 29; 47…

Primary: The Percentage of Participants With a ≥ 2-grade Improvement From Baseline on the Facial Wrinkle Scale With Photonumeric Guide (FWS) According to INVESTIGATOR AND…