N/A N=25 Observational Study of Ocular Inflammation in Patients Undergoing a Pars Plana Vitrectomy
Vitrectomy
Primary: Percentage of Participants With Vitreous Cell Count of 0 — 88.0 Percentage of participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=35 Vitreous Inflammation in Standard and Heavy Silicone Oil
Vitreous Inflammation
Primary: Vitreous Prostaglandin E2 Levels — 369.38; 869.16 pg/mL
N/A N=20 Acupuncture for Reduction of Inflammation
Thyroid or Parathyroid Surgery
Primary: Reduced Pain Medication Requirement — 5.43; 7.36 mg of Morphine
N/A N=75 Investigation of the Effects of H-PRF on the Period After Impacted Third Molar Tooth Extraction
Impacted Third Molar Tooth
Primary: Postoperative Facial Swelling (Sum of 3 Linear Distances, mm) — 122.08; 118.55; 116.90; 119.68 Millimeters (mm)
Phase 3 N=178 Clinical Study of the Efficacy of the Ophthalmic Emulsion PRO-145 for Inflammation and Pain After Phacoemulsification
Cataract
Primary: Visual Ability (VA) — 0.91; 0.87 units on a scale (LogMAR) — p=0.065
Phase 4 N=55 Effect IV Ibuprofen and Inflammatory Responses
Gallbladder Disease
Primary: Stress Response Inflammation Markers :Cortisol and C Reactive Protein (CRP) — 173.6; 289.5; 17; 17 pg/mL
N/A N=50 Prolensa (Bromfenac) 0.07% QD vs. Ilevro (Nepafenac) 0.3% QD for Treatment of Ocular Inflammation Post Cataract Surgery
Cataract · Retinal Edema · Inflammation
Primary: Treatment of Inflammation Associated With Cataract Surgery — 0.01; 0.01 units on a scale
N/A N=179 Persistent Postoperative Pain and Joint Stiffness After Total Knee Arthroplasty Performed for Osteoarthritis
Pain · Joint Stiffness
Primary: Presence of Persistent Postoperative Pain Using the Numeric Rating Scale (NRS) — 10 Participants
Phase 1 N=70 Inflammatory Markers in Trauma Patient Outcomes
Polytrauma
Primary: Length of Hospital Stay — 7; 8 days — p==0.275
Phase 3 N=46 Cytokine Removal in Cardiopulmonary Bypass Patients
Elective Cardiac Surgical Interventions
Primary: IL-6 — 0; 0; 0; 0 pg/ml
Phase 2 N=24 Oxidative Stress and Surgical Recovery
Surgical Recovery · Pain, Postoperative
Primary: Phosphorylation of STAT-3 in MDSC (Myeloid-derived Suppressor Cells) — 2.162; 2.025 STAT3 archsinh ratio — p=0.5490
N/A N=138 Surgical Stress Markers for Postoperative Complications: a Prospective Study
Operative Procedures, Complications
Primary: Predictive Value of Postoperative Albumin Decrease in Terms of Surgical Stress and Postoperative Complications — 11.3 g/L
Phase 4 N=94 No Drop Post-Op Cataract Surgery
Cataract
Primary: Best Corrected Visual Acuity (BCVA) (Pre-op) — .28 LogMar
Phase 2 N=172 Efficacy and Safety of IBI-10090 in Ocular Surgery Patients
Inflammation Associated With Cataract Surgery
Primary: Anterior Chamber Cell Count at Day 8 Post-Treatment — 50; 51.8; 60.3 percentage of patients with ACC clearing
N/A N=298 Prevena™ Incisional Negative Pressure Wound Therapy in Re-operative Colorectal Surgery
Surgical Site Infection
Primary: Occurrence of Superficial Surgical Site Infection — 11; 21; 107; 128 Participants
Phase 4 N=50 Continuous Wound Infiltration After Hallux Valgus Surgery
Hallux Valgus
Primary: Average Postoperative Numeric Rating Scale (NRS) for Pain — 2.0; 1.9 units on a scale — p=0.596
N/A N=174 Evaluation of the Predictive Nature of the Postoperative CRP on Postoperative Recovery in Patients Undergoing Colorectal Resection (CRP-Track)
Colorectal Postoperative Complication
Primary: C-reactive Protein Rate — 47.9; 81.0; 50.0; 79.5 percentage
Phase 4 N=30 Steroids in Bilateral Total Knee Replacement
Postoperative Inflammatory Response
Primary: Decrease in IL6 Level — 359.4; 381.6 pg/ml
N/A N=50 Inflammation and Postoperative Tramadol Analgesia
General Surgery
Primary: Analgesic Affect of Tramadol After Major Abdominal Surgery — 7; 5; 5; 3 Score on a scale
Phase 4 N=15 Healing Ointment Usage Post-surgical Procedure
Surgical Wound
Primary: Objective Erythema Assessment Using Clinical Grading Analog Scale — 0.8; 0.83; 0.75; 0.29 score on a scale
Phase 3 N=458 Renin-angiotensin-aldosterone System (RAAS), Inflammation, and Post-Operative Atrial Fibrillation (AF)
Atrial Fibrillation
Primary: Postoperative Atrial Fibrillation — 27.2; 27.8; 25.9 percentage of patients — p=0.95
Phase 4 N=343 PAIN - Postoperative Analgesia INvestigation
Postoperative Pain
Primary: Postoperative Pain as Assessed by a Numeric Pain Scale (NPS) — 5.05; 5.02 units on a scale — p=0.934
Phase 3 N=203 Ketorolac in Breast Cancer Surgery
Curative Breast Cancer Surgery · Inflammatory Positive/Negative Status · Pre Surgical Incision Administration
Primary: Recurrence-free Survival — 80; 96 Participants
Phase 2 N=86 The Influence of Postoperative Analgesia on Systemic Inflammatory Response and POCD After Femoral Fractures Surgery
Postoperative Cognitive Dysfunction
Primary: Interleukin-6 Concentration in Peripheral Blood. — 27.2; 26.6; 104; 97.7 pg/ml
Phase 4 N=120 Post Operative Sore Throat and Dexamethasone
Sore Throat · Pain
Primary: Subjects Assessment of Sore Throat Pain at 24 Hours — 4; 4; 5 units on a scale (1 to 5) — p=<0.001
N/A N=204 Impact of Opioid Free Anesthesia on Outcome After DIEPflap Surgery
Major and Minor Surgical Complications
Primary: Number of Patients With One or More Complications — 10; 85 Participants — p=<0.001
Phase 4 N=50 A Comparison of Post Phacoemulsification Aqueous Flare in Patients Using Ketorolac 0.45% 2 Times Daily (BID) and Bromfenac 0.09% 2 Times Daily (BID)
Post Operative Anterior Chamber Inflammation (Flare)
Primary: Anterior Chamber Inflammation (Flare) — 24.48; 21.93 photon count per msec (pc/ms)
Phase 3 N=48 Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic Meniscus Surgery
Meniscus Tear, Tibial · Pain, Postoperative · Postoperative Complications
Primary: Pain Levels Recorded With a Visual Analogue Scale — 25.6; 28.8 score on a scale
Phase 4 N=68 Effect of Steroid for the Postoperative Swelling After Orthognathic Surgery
Swelling
Primary: Effect of Perioperative Steroid for the Postoperative Swelling After Orthognathic Surgery — 167.06; 190.73; 61.39; 57.62 ml — p=>0.05
N/A N=178 Post-op Acetaminophen vs NSAID Use on Lumbar Spinal Fusion Outcomes
Lumbar Osteoarthritis · Spondylosis · Lumbar Disc Disease
Primary: Perioperative Opioid Use — 86.25; 306.6; 192.4; 88.95 oral morphine equivalents (OME) (mmg) — p=<0.001