N/A N=400 Timing of Antibiotic Prophylaxis for Cesarean Deliveries
Infection
Primary: Endometritis and Wound Infection — 6; 4 patients infected
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=121 Procalcitonin-Guided Decision Making to Shorten Antibiotic Therapy in Suspected Neonatal Early-Onset Sepsis
Sepsis
Primary: Antibiotic Treatment for More Than 72 Hours — 33; 55 participants — p=0.002
N/A N=65 Utility of Placental/Umbilical Cord Blood in Early Onset Neonatal Sepsis in Very Low Birth Weight Infants
Preterm Infant · Early-Onset Neonatal Sepsis · Umbilical Cord
Primary: White Blood Cell Count (WBC) (1) — 8257 ratio of cells/mm3
N/A N=995 Neonatal Outcome by Reason for Delivery
Preterm Delivery
Primary: Composite Perinatal Morbidity — 277; 203; 221; 45 participants
N/A N=37 Physical Therapy Intervention for Puerperal Mastitis
Mastitis
Primary: Breast and Nipple Pain — 0; 0; 1 score on a scale
Phase 2 N=21 A Study to Evaluate SAGE-547 in Participants With Severe Postpartum Depression
Severe Postpartum Depression
Primary: Change From Baseline at End of Treatment Period (at 60 Hours) in Hamilton Rating Scale for Depression (HAM-D) Total Score — -8.75; -20.97 score on a scale — p=0.008
N/A N=28 Sepsis-Associated Purpura Fulminans International Registry - Europe
Sepsis
Primary: Mortality — 11 Participants
N/A N=106 Postpartum Pre-exposure Prophylaxis (PrEP) Study to Evaluate an Adherence Promotion Package for Postpartum Women on PrEP
HIV-1-infection
Primary: Recent PrEP Adherence — 33; 18 Participants — p=<0.001
N/A N=44 Reduction of Endometritis After Cesarean Section With the Routine Use of Methergine
Endometritis
Primary: Endometritis Incidence — 0; 0 participants
N/A N=106 Accuracy of Blood Loss Estimation After Vaginal Delivery
Postpartum Hemorrhage
Primary: Difference in Actual Blood Volume and Estimated Blood Volume in Milliliters. — -20.8; -41.7; -53.5; -96.0 milliliters — p=<0.05
Phase 2 N=4 Evaluate SAGE-547 in Female Participants With Severe Postpartum Depression
Postpartum Depression
Primary: Number of Participants With Treatment Emergent Adverse Events (TEAEs) and Treatment Emergent Serious Adverse Events (TESAEs) — 4; 0 Participants
N/A N=320 Improving Women's Health Through Coordinated Postpartum Planning
Maternal Death · Maternal Morbidity
Primary: Number of Participants Attending a Comprehensive Postpartum Visit — 84; 89 Participants
N/A N=24 Coagulation Factor Changes Associated With Postpartum Hysterectomies
Obstetric Labor Complications · Hemorrhage · Complications; Cesarean Section
Primary: Fibrinogen Level at 2 Hours After Delivery — 186; 418 mg/dL — p=<0.05
N/A N=120 Prophylactic Incisional Care in Obese Women at Cesarean
Wound Infections
Primary: Number of Participants With Composite Surgical Site Infection (SSI) or Other Wound Complication. — 5; 3 Participants — p=0.72
N/A N=1,064 Effect of Prophylactic Negative Pressure Versus Silver Impregnated Silicone Bandage on C-Section Infection Rates
D001458 · D011247
Primary: Infection Rate — 17; 18; 5; 5 Participants
Phase 4 N=56 Postpartum HPV Vaccination
HPV-Related Malignancy
Primary: Patient Indication of Willingness to Accept the Vaccine Based on Survey — 56 Participants
N/A N=22 Piperacillin PK Analysis in Severe Sepsis Patients
Sepsis · Severe Sepsis
Primary: 100% f T>MIC: Free Piperacillin Concentration Maintained Above the MIC Throughout the Dosing Interval. — 4 participants
N/A N=106,629 Effects of Code Sepsis Implementation on Emergency Department (ED) Sepsis Care
Sepsis
Primary: Door-to-antibiotic Time — 160; 146; 139; 140 minutes — p=<0.001
N/A N=343 Comprehensive Postpartum Management for Women With Hypertensive Disorders of Pregnancy
Hypertension, Pregnancy-Induced · Postpartum Preeclampsia · Hypertension; Maternal
Primary: Proportion of Participants With Recorded Blood Pressure Values in Office — 43; 44; 49; 56 Participants
N/A N=36 Neurophysiology of Postpartum Depression in an Experimental Model of Pregnancy and Parturition
Postpartum Depression
Primary: Blood-oxygen-level-dependent (BOLD) Response During Functional Magnetic Resonance Imaging (fMRI) z Statistic — 2.3; 2.0; 2.1; 1.7 z score — p=.27
N/A N=110 Negative Pressure Wound Therapy After Cesarean Delivery
Major Puerperal Infection, Postpartum · Wound Complications · Wound Seroma
Primary: Wound Complication Rate — 3; 1; 3; 6 participants
Phase 4 N=67 Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries
Pain · Postpartum Depression
Primary: Perineal Pain in Postpartum Patients 1 Week After Obstetric Anal Sphincter Injuries. — 3.5; 2.7; 2.4 score on a scale
N/A N=220 Improving Health Outcomes and Equity by Targeting Postpartum Mothers at Highest Risk
Maternal Behavior · Postpartum Depression
Primary: Emergency Department (ED) Visits and Readmissions — 18; 21 Postpartum Hospital Use
N/A N=575 Persistent Pain After CS Delivery
Persistent Pain After Delivery
Primary: Persistent Pain-PERCEIVED STRESS Scores Stratified by the Rate of Recovery — 11.4; 12.9; 15.4 units on a scale — p=<0.01
N/A N=87 Fourth Trimester - A Web-based Tool for Postpartum Care to Address the Needs of Underserved Women
Pregnancy Related · Postpartum Sadness
Primary: Change From Baseline Resilience at 4 Weeks — 26.57; 28.29; 1.85 score on a scale — p=<.001
Phase 2 N=98 Antibiotic "Dysbiosis" in Preterm Infants
Enterocolitis, Necrotizing · Bacteremia · Bronchopulmonary Dysplasia
Primary: Number of Events of Composite Morbidities and Mortality, Including Necrotizing Enterocolitis (NEC), Late Onset Sepsis (LOS), Bronchopulmonary Dysplasia (BPD) and Death…
N/A N=61 CSE v. Epidural for Postpartum Depression
Depression, Postpartum · Labor Pain
Primary: Edinburgh Postnatal Depression Score (EPDS) — 4.23; 4.71 score on a scale — p=0.7463
Phase 4 N=55 Tdap Vaccine in Post-Partum Women
Diphtheria · Pertussis · Tetanus
Primary: Geometric Mean Fold Rise in Serum Immunoglobulin G (IgG) by ELISA at Week 2 — 4.8; 8.6; 21.6; 22.4 Fold Rise
N/A N=99 Postpartum Wellness
Postpartum Depression
Primary: Depression Symptoms — 10.1; 11 score on a scale
N/A N=175 PREPP: Preventing Postpartum Depression
Postpartum Depression (PPD)
Primary: Score on the Edinburgh Postnatal Depression Scale (EPDS) — 5.04; 4.36; 4.43; 4.04 score on a scale