N/A N=80 Knee Bracing for People With Patellofemoral Osteoarthritis
Knee Osteoarthritis
Primary: Change in Pain on the VIsual Analog Scale (VAS) — -.068 change in units on a scale from baseline
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=157 Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee
Osteoarthritis, Knee
Primary: Change From Baseline in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Domain Score at Week 2 — -3.64; -3.15 Units on a scale — p=0.39
Phase 2 N=1,457 A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee
Osteoarthritis
Primary: Rate of Progression of Joint Space Narrowing — -0.101; -0.125; -0.109 mm/year — p=0.508770
N/A N=50 Osteoarthritis Structural Changes Assessed by Magnetic Resonance Imaging and Neuropathic Pain in Knee Osteoarthritis
Neuropathic Pain · Knee Osteoarthritis
Primary: Osteoarthritis Structural Changes Assessed by Quantitative Magnetic Resonance Imaging With and Without Neuropathic Pain — 14; 7; 5; 1 participants
N/A N=10 A Biologic Joint Replacement Strategy to Treat Patients With Severe Knee Trauma and Post-Traumatic Knee Osteoarthritis
Post-traumatic Osteoarthritis
Primary: Visual Analogue Scale Pain Score — 2.3 units on a scale
N/A N=3,000 Development of an Osteoarthritis (OA) Care Plan to Improve Process and Quality of OA Treatment Decisions
Osteo Arthritis Knee · Osteoarthritis, Hip
Primary: Differences in Decision Conflict Scale With ASK vs Usual Care — 25.1; 26.0 Score on a scale
N/A N=100 Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement
Osteoarthritis of the Knee
Primary: Change in KOOS4 From Baseline (Knee Injury and Osteoarthritis Outcome Score) — 16.0; 32.5 units on a scale
Phase 2 N=260 Exploratory Study of PENNSAID Gel to Treat Symptoms of Knee Osteoarthritis
Osteoarthritis of the Knee
Primary: Pain When Walking On A Flat Surface — 0; 1; 8; 4 Participants
N/A N=76 Home Rehabilitation in Patients After Primary Total Knee Arthroplasty
Osteoarthritis · Rehabilitation
Primary: Total WOMAC Score — 51.64285714; 52.47619048; 39.60714286; 40.38095238 score on a scale
N/A N=1,261 Survey of Osteoarthritis Real World Therapies (MK-0663-140)
Osteoarthritis
Primary: Percentage of Participants Who Reported Adequate vs. Inadequate Pain Relief at Baseline — 46.2; 53.8 Percentage of Participants
N/A N=101 Role of Bone in Knee Osteoarthritis (OA)
Osteoarthritis, Knee
Primary: Number of Participants With Viable Specimens for Genetic Analysis — 14 participants
N/A N=23 In Vivo Three-Dimensional Determination of Osteoarthritis Brace Effectiveness
Osteoarthritis, Knee
Primary: Medial Condylar Separation With Brace — 0.60 mm
Phase 3 N=164 A Study on Visco-antalgic Intra-articular Administration in Symptomatic Knee Osteoarthritis
Knee Osteoarthritis
Primary: Change From Baseline in WOMAC VA3.1 Pain Subscale Score at Month 6 — -23.6; -14.1 mm — p=0.141
Phase 1 N=8 Safety, Tolerability and Pharmacokinetics of Intraarticular 4P004 Single Dose in Patient With KL 2-4 Osteoarthritic Knee
Knee Osteoarthritis
Primary: Safety and Tolerability of Single IA Administration of 4P-004 at Escalating Doses in Participants With Knee OA. — 5; 5; 5; 6 participants
N/A N=100 Structured Non-operative Treatment of Knee Osteoarthritis
Osteoarthritis of the Knee
Primary: Change From Baseline in KOOS4 (Knee Injury and Osteoarthritis Outcome Score) — 18.2; 7.1 units on a scale
N/A N=27 Muscle Weakness and Post-traumatic Knee OA
Meniscectomy
Primary: Change in International Knee Documentation Committee (IKDC) Subjective Knee Form Score — 22.2; 20.6 units on a scale
N/A N=144 Intra-articular Polyacrylamide Hydrogel in Knee Osteoarthritis
Osteoarthritis
Primary: Change of the Total WOMAC Score (WOMAC-T) — -624.12; -444.82; -605.61; -426.31 score on a scale — p=0.00030
N/A N=57 Intra-articular Polyacrylamide Hydrogel in the Treatment of Knee Osteoarthritis
Osteoarthritis, Knee
Primary: Change in the Total WOMAC Score (WOMAC-T) — 1137.13; 767.47; 1271.60; 445.33 score on a scale — p=0.00
N/A N=162 Calypso Knee System Clinical Study, OUS
Osteoarthritis, Knee
Primary: Percentage of Participants With Composite Clinical Success (CCS) — 83.5; 57.2 percentage of subjects
N/A N=179 Persistent Postoperative Pain and Joint Stiffness After Total Knee Arthroplasty Performed for Osteoarthritis
Pain · Joint Stiffness
Primary: Presence of Persistent Postoperative Pain Using the Numeric Rating Scale (NRS) — 10 Participants
Phase 3 N=380 Effect of Diacerein vs Celecoxib on Symptoms and Structural Changes in Symptomatic Knee Osteoarthritis
Osteoarthritis · Osteoarthritis, Knee
Primary: Change Form Baseline in WOMAC A Pain Subscale — -11.14; -11.82 cm — p=<0.025
N/A N=64 Needling Techniques for Knee Osteoarthritis
Knee Osteoarthritis · Kidney Yin Deficiency · Kidney Yang Deficiency
Primary: WOMAC Total in Week 15 — 11.6; 54.4 score on a scale — p=<0.001
N/A N=23 Skeletal Muscle Atrophy and Dysfunction Following Total Knee Arthroplasty
Knee Osteoarthristis
Primary: Cross-sectional Area (CSA) of Muscle Fibers — 2680; 2377; 2028; 1882 micron squared
N/A N=7 Preventing Posttraumatic Osteoarthritis With Physical Activity Promotion
Anterior Cruciate Ligament Injuries · Exercise · Cartilage, Articular
Primary: T1rho Relaxation Times in the Medial Femoral Condyle at Baseline — 53.48 ms
Phase 4 N=99 Efficacy of Ipack Block and Surgeon's Joint Infiltration in Total Knee Arthroplasty
Osteo Arthritis Knee
Primary: Narcotic Consumption — 15.87; 13.67 morphine equivalents, mg
N/A N=293 Effect Of Meloxicam Versus Placebo In Mainland Chinese Patients With Osteoarthritis Of The Knee
Osteoarthritis of the Knee
Primary: The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Total and the 3 Subscales Scores (Pain, Stiffness and Physical Function) at Screening 1 by…
N/A N=99 Time-dependent Improvement of Functional Outcome Following Oxford Medial Unicondylar Knee Replacement
Osteoarthritis
Primary: Knee Injury and Osteoarthritis Outcome Score — 85.5; 88.2 units on a scale
N/A N=79 Gait Modification Treatment for Knee Osteoarthritis
Knee Osteoarthritis
Primary: Change From Baseline to Week 17 and From Baseline to Week 21 in Pain as Measured by Numerical Rating Scale — -2.1; -1.8; -2.2; -1.5 units on a scale — p=0.495
Phase 3 N=697 Tanezumab in Osteoarthritis of the Knee
Arthritis · Osteoarthritis
Primary: Change From Baseline in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Subscale at Week 16: Baseline Observation Carried Forward (BOCF)…
Phase 2 N=30 Treatment of Knee Osteoarthritis With Allogenic Mesenchymal Stem Cells
Osteoarthritis, Knee · Arthritis of Knee · Knee Osteoarthritis
Primary: Number of Participants With Adverse Events as a Measure of Safety and Tolerability — 14; 13 participants