N/A N=3,889 Improve Sudden Cardiac Arrest Study
Sudden Cardiac Arrest · Ventricular Arrythmia
Primary: Time to the First Occurrence of a Ventricular Arrhythmia — 32.5; 18.3 Estimated 24-Month VT-VF Pct of Patients
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 1 N=192 Automatic External Defibrillation Monitoring in Cardiac Arrest
Death, Sudden, Cardiac · Ventricular Fibrillation · Tachycardia, Ventricular
Primary: Number of Participants Without Defibrillation — 94; 97 participants
N/A N=2,348 Vest Prevention of Early Sudden Death Trial and VEST Registry
Myocardial Infarction · Ventricular Dysfunction · Sudden Death
Primary: Sudden Death Mortality — 25; 19 Participants
N/A N=15 ECPR for Refractory Out-Of-Hospital Cardiac Arrest
Cardiac Arrest · Heart Arrest · Sudden Cardiac Arrest
Primary: Emergency Department Arrivals Under 30 Minutes — 5 Participants
N/A N=1,076 Improving Cardiac Arrest Diagnostic Accuracy of Emergency Medical Dispatchers
Cardiac Arrest
Primary: Number of Participants With Agonal Breathing — 176; 87 Participants
N/A N=2,595 Assessment of Primary Prevention Patients Receiving An ICD - Systematic Evaluation of ATP
Sudden Cardiac Death
Primary: All-Cause Shock — 129; 178 Participants — p=0.005
N/A N=1,173 Understanding Outcomes With the EMBLEM™ S-ICD in Primary Prevention Patients With Low Ejection Fraction
Ventricular Fibrillation · Ventricular Tachycardia · Low Cardiac Output
Primary: Percentage of Patients Who Did Not Experience an Inappropriate Shock From Their EMBLEM S-ICD — 95.9 Percentage of participants
Phase 2 N=8 Healthy Heart Habits
Acute Coronary Syndrome · Depression
Primary: Acceptability Measured by the Client Satisfaction Questionnaire — 30.57 score on a scale
N/A N=48 Hemodynamic Effects of Standard Cardiopulmonary Resuscitation (CPR), Active Compression Decompression CPR With an Inspiratory Impedance Device, and Standard CPR With an Intrathoracic Pressure Regulator During Out-of-hospital Cardiac Arrest
Cardiac Arrest · Sudden Cardiac Death
Primary: Mean Systolic and Diastolic Blood Pressures — 80.38; 121.21; 61.37; 15.52 mmHg
Phase 3 N=193 Psychological Support for Patients With an Implantable Cardioverter Defibrillator
Anxiety · Depression
Primary: Hospital Anxiety and Depression Scale - Depression Scale at Baseline — 4.70; 7.47; 5.35; 4.12 units on a scale
N/A N=342 Amiodarone for the Prevention of Reperfusion Ventricular Fibrillation
Other Intraoperative Cardiac Functional Disturbances During Cardiac Surgery
Primary: Participants Experiencing Ventricular Fibrillation Requiring Defibrillation During the 60 Minute Period Following Myocardial Reperfusion — 66; 60; 70 Participants…
N/A N=523 Risk Stratification in Patients With Preserved Ejection Fraction
Myocardial Infarction
Primary: Number of Participants With Major Arrhythmic Events (MAEs) - Present When One of the Following Occurred: Sudden Cardiac Death, Sustained Ventricular Tachycardia, or…
N/A N=677 Unexpected Cardiac Arrest in Intensive Care Unit
Heart Arrest
Primary: Number of Patients With Unexpected Cardiac Arrest — 677; 30,722 Participants
Phase 3 N=295 Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-OH [Out of Hospital] Trial
Cardiac Arrest
Primary: Survival With Good Neurobehavioral Outcome — 27; 15; 111; 107 Participants — p=0.14
Phase 4 N=100 The Use of Dual Chamber ICD With Special Programmed Features to Lower the Risk of Inappropriate Shock
Ventricular Tachycardia · Ventricular Fibrillation · Atrial Fibrillation
Primary: Number of Subjects Inappropriately Shocked by Implantable Cardioverter-Defibrillator (ICD) — 1; 1 Participants — p=1.0
N/A N=48 Acute Subcutaneous Defibrillation
Ventricular Arrhythmias
Primary: Subjects Will Demonstrate a Successful Defibrillation Outcome if They Have 2 Successful Defibrillation Shocks With the Research System. — 85.7 percentage of success
Phase 3 N=89 Implantable Cardioverter-Defibrillator Use in the VA System
Cardiomyopathies
Primary: Referral for Implantable Cardioverter Defibrillator — 11; 1 participants
Phase 2 N=397 Calcium for Out-of-Hospital Cardiac Arrest
Heart Arrest, Out-Of-Hospital
Primary: Number of Participants With Sustained Return of Spontaneous Circulation — 37; 53 Participants
N/A N=180 Pan-Asia United States PrEvention of Sudden Cardiac Death Catheter Ablation Trial
Ventricular Tachycardia (VT)
Primary: Freedom From Recurrent VT, Cardiovascular Rehospitalization, and All-cause Mortality — 33; 25; 28; 27 Participants
N/A N=2,260 Effectiveness of Dispatch-Assisted Cardiopulmonary Resuscitation (CPR) Instructions
Cardiac Arrest
Primary: Sensitivity — 1012 Participants
N/A N=354 Heart Failure and Sudden Cardiac Death Japan Registry
Heart Failure · Arrhythmias, Cardiac · Sudden Cardiac Death
Primary: Number of Participants With Ventricular Arrhythmia Associated Symptoms - ICD/CRT-D Cohorts — 3; 8 Participants
N/A N=274 Pre-arrival Instructions Effect on Bystander Cardiopulmonary Resuscitation (CPR).
Heart Arrest · Cardiac Arrest · Cardiopulmonary Arrest
Primary: Incidence of Bystander Cardiopulmonary Resuscitation (CPR) in Out of Hospital Cardiac Arrest (OHCA) — 11; 19; 42; 25 participants — p=0.41
N/A N=55 Subcutaneous Implantable Defibrillator (S-ICD) System - CE Clinical Investigation
ACC/AHA/NASPE Class 1, IIa or IIb Indications
Primary: Conversion of Induced Ventricular Fibrillation — 52 Participants
Phase 2 N=10 Coenzyme Q10 in Post-Cardiac Arrest Cerebral Resuscitation
Cardiac Arrest · Sudden Cardiac Arrest
Primary: Prevalence of Low Serum CoQ10 Levels in Cardiac Arrest Patients — 0.706; 0.66 ug/mL
Phase 3 N=3,024 Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or Tachycardia
Cardiac Arrest
Primary: Number of Participants Who Survive From the Time of Cardiac Arrest to Hospital Discharge — 237; 233; 222 participants
Phase 3 N=1,359 Induction of Mild Hypothermia Following Out-of-hospital Cardiac Arrest
Out-of-hospital Cardiac Arrest
Primary: Number Alive at Hospital Discharge — 187; 183; 62; 76 participants
N/A N=329 Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-IH [In Hospital] Trial
Cardiac Arrest
Primary: Survival With Good Neurobehavioral Outcome — 48; 48; 85; 76 Participants — p=0.63
N/A N=101 Prevention of Syncope by Cardiac Pacing in Patients With Bifascicular Block
Bifascicular Block · Syncope
Primary: Combined Endpoint Defined as First Occurrence Among the Following Events 1)Syncope Episode of Any Origin; 2)Presyncopal Episode With Documented Cardioinhibitory Origin…
N/A N=354 Full Automaticity and Remote Follow-up
Tachyarrhythmia
Primary: Remote Follow-up as an Alternative to Onsite Visit — 203 Participants
N/A N=4,231 Circulation Improving Resuscitation Care (CIRC)
Cardiac Arrest · Cardiopulmonary Resuscitation
Primary: Hospital Discharge — 196; 233 participants