N/A N=98 Clinical Comparison of Vital Pulp Capping Restorative Protocols
Deep Dental Caries
Primary: Success Rate Based on Pulp Vitality Tests (Vital/Non Vital) — 96.2; 100; 100; 86 Percentage of success rate — p=>0.1
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=24 Use of Mineral Trioxide Aggregate in the Treatment of Traumatized Teeth
Periapical Diseases
Primary: Changes Between Initial and Post Treatment Dimensions of Periapical Lesions — 37.34; 34.04; 16.20; 17.54 square millimeters — p=<0.01
Phase 3 N=169 Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth
Caries · Dental Pulp Exposure
Primary: Parameters Evaluated After Treatment — 19; 19; 25; 3 Participants
Phase 4 N=60 Theracal Pulpotomy in Primary Molars
Deep Caries
Primary: Clinical Examination — 30; 30 Participants
N/A N=36 The Use of Platelet Rich Fibrin in Pulpal and Periodontal Regeneration in Mature Teeth
Pulpal Necrosis
Primary: Vitality of Teeth (Units) Using Thermal and Percussion Sensitivity Trend Observed During Study Duration (3-11 Months) — .559; .592; .065; .040 Teeth
N/A N=36 Encapsulated Mesenchymal Stem Cells for Dental Pulp Regeneration.
Periapical Periodontitis
Primary: Number of Participats Showing Efficacy (Functionality) — 18; 18 Participants
N/A N=101 Evaluation of Hyaluronic Acid Pulpotomies in Primary Molars
Pulpitis
Primary: Number of Teeth Sensitive to Percussion in 3 Groups — 7; 6; 3 teeth — p=>0.05
Phase 2 N=70 MTA/FS Pulpotomy for Vital Primary Incisors: A Randomized Controlled Trial
Dental Caries · Dental Pulp Exposure
Primary: Comparison of MTA/FS Pulpotomy Versus RCT Treated Incisors With Acceptable Radiographic Outcome at 12 Months Post-procedure. — .97; .92 Proportion of incisors — p=.15
N/A N=30 Diagnostic Device for the Assessment of Pulpal Blood Flow
Dental Pulp Test
Primary: Subjective Tooth Assessment: Number of Teeth With Normal and Abnormal Pulp — 111; 32 Teeth
N/A N=4 Nanodiamond Modified Gutta Percha (NDGP) Composite for Non-surgical Root Canal Therapy (RCT) Filler Material
Dental Pulp Diseases · Dental Pulp Necrosis · Nerve Root Pain Nec
Primary: Percent Reduction in Apical Radio-lucency — 17.4; 27.1 % Change in Diameter (mm)
Phase 4 N=64 Assessing Success of MTA and Pre-mixed Bioceramic in Mature Teeth With Irreversible Pulpitis With Full Pulpotomy.
Pulpitis - Irreversible
Primary: Clinical Success at 6 Months — 27; 30 Participants
N/A N=194 Post-endodontic Pain Survey
Postoperative Pain · Endodontic Disease · Obturation
Primary: Visual Analogue Scale (VAS) — 4.06; 2.68; 2.41; 2.27 score on a scale
N/A N=15 A New Approach for Controlling Hemostasis During Canal Treatment: a Pilot Study
Blood Contamination of Root Canal During Endodontic Therapy
Primary: Change From Baseline in Root Canal Bleeding Score — 2.33; 0.13 score on a scale — p=<.0001
N/A N=86 Bone Regenerative Techniques in Endodontic Microsurgery
Apical Periodontitis
Primary: 2D Radiographic Healing at 12 Months Follow up (Overall Cases) — 24; 29; 1; 1 osteotomy site
Early Phase 1 N=46 Pain Management in Teeth With Reversible Pulpitis
Reversible Pulpitis · Ibuprofen
Primary: Change in Pain Intensity From Baseline (Pre-Operative) to Immediately During the Procedure (Day 0), Measured by the Visual Analogue Scale (VAS) — 5.05; 0.64 score on a…
N/A N=132 Effects of Different Irrigation Activation Techniques on the Healing of Large Periapical Lesions
Periapical Periodontitis · Irrigation Activation · Lasers
Primary: Post-operative Diameter of the Periapical Lesion — 2.07; 0.98; 1.12; 0.78 Post-operative lesion diameter- mm2
Phase 1 N=84 Effect of Triple Antibiotic Paste as an Intracanal Medication With an Anti-Inflammatory Drug on Post-operative Pain.
Asymptomatic Necrotic Teeth
Primary: Post Operative Pain — 3.18; 2.27; 2.20; 1.39 score on a scale — p=0.083
N/A N=60 A New Approach for Controlling Hemostasis During Canal Treatment
Blood Contamination of Root Canal During Endodontic Therapy
Primary: Change From Baseline in Root Canal Bleeding — 3.40; 3.73; 0.26; 3.03 millimeters — p=<.0001
N/A N=43 Ridge Preservation Following Tooth Extraction Using Two Mineralized Cancellous Bone Allografts
Alveolar Bone Loss
Primary: % Vital Bone Formation (Histological) — 27.19; 24.08 percentage
N/A N=80 Study of Root Coverage With Acellular Dermal Matrix: Puros® Dermis Versus Alloderm®
Gingival Recession
Primary: Non -Inferiority of Dermis to Alloderm — 2.06; 2.00 mm
N/A N=160 Success Rate of 4 Injection Protocols for Mandibular First Molars With Symptomatic Irreversible Pulpitis
Root Canal Infection
Primary: Number of Participants With Successful Injection Technique Assessed by Verbal Rating Scale (VRS) — 16; 37; 29; 26 Participants
N/A N=376 Pulp Capping With Two Different Agents
Dental Pulp Exposure
Primary: Tooth Survival — 158; 130 participants — p=.046
N/A N=60 Survival of Endocrowns Made From Different Ceramics
Pulp Disease, Dental · Dental Caries · Dental Leakage
Primary: Survival of Dental Prosthesis — 19; 14; 17 Teeth
Phase 3 N=983 Prevention of Adult Caries Study (PACS)
Caries, Dental
Primary: Total Net D12FS Caries Increment (Total of Non-cavitated Lesions (D1), Cavitated Lesions (D2) and Sound Surfaces (S)) — 2.43; 2.68 weighted increment units/13 months…
Phase 3 N=80 Role of Propolis Paste in Preventing Pain After Root Canal Treatment.
Pain, Postoperative
Primary: Pain Intensity Measure: Visual Analogue Pain Scale — 11.8; 8.8; 9.4; 10.3 score on a scale — p=0.329
N/A N=70 RCT of Pulp Capping Over Carious Exposure in Adults
Carious Exposure · Human Permanent First and Second Molars · Mature Teeth
Primary: Survival of Capped Pulps — 842; 1201 Survival days — p=<0.01
N/A N=32 Effects of Photobiomodulation on Postoperative Pain After Primary Endodontic Therapy in Molars With Symptomatic Apical Periodontitis
Postoperative Pain
Primary: Pain as Assessed by the Visual Analog Scale — 0; .33 score on a scale
Phase 4 N=21 Wound Management for Sacral Pressure Ulcers With Necrotic Tissue
Pressure Ulcers
Primary: Percentage of Wounds Healed — 63.1; 6.1 percentage of wounds
Phase 4 N=24 Management of Mandibular ORN: PENTO as Medical Treatment
Osteoradionecrosis
Primary: Bone and/or Tissue Healing as Measured With the Classification of ORN Stages, Area of Bone Exposed (mm2) and Radiological Findings (OPG). — 14; 15; 13; 15 mm2
N/A N=51 CopiOs® Pericardium Membrane for Localized Alveolar Ridge Augmentation
Alveolar Ridge Defect
Primary: Change in Horizontal Ridge Widths From Baseline to 6 Months — 2.61 mm