N/A N=300 The Effect of Age on the Incidence of Postoperative Residual Neuromuscular Blockade
Residual Neuromuscular Blockade in Elderly Patients
Primary: Incidence of Residual Neuromuscular Blockade — 45; 86 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=302 Residual Curarization and Its Incidence at Tracheal Extubation (P08194)
Observation of Neuromuscular Block
Primary: Percentage of Participants With Residual Neuromuscular Blockade (NMB)(Train of Four [TOF] Ratio <0.9) at Time of Tracheal Extubation — 56 percentage of participants
N/A N=350 Incidence of Incomplete Postoperative Neuromuscular Recovery From Anesthesia (P07535)(Completed)
Neuromuscular Blockade
Primary: Number of Participants With Train-of-four (TOF) Ratio <0.9 at PACU Arrival — 91 participants
N/A N=366 Incidence of Postoperative Residual Neuromuscular Blockade in Portugal
Residual Neuromuscular Blockade · Residual Paralysis, Post-Anesthesia · Observational Study
Primary: Percentage of Patients With Postoperative Residual Neuromuscular Blockade — 20 Participants
Phase 4 N=200 The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications
Postoperative Complications · Neuromuscular Blockade
Primary: Number of Participants With a Postoperative Pulmonary Complication — 33; 40 Participants
Phase 4 N=163 Best Practice Using Rocuronium and Reversal With Neostigmine or Sugammadex
Muscle Weakness
Primary: Incidence of Postoperative Residual Neuromuscular Blockade at Time of Arrival to the Post-anesthesia Care Unit. — 5 Participants
Phase 4 N=81 Impact of Anesthetic Choice (Sevoflurane Versus Desflurane) on Airway Reflex Recovery in the Context of Antagonized Neuromuscular Block
Airway Reflexes, Protective · Recovery After Neuromuscular Block · Anesthetic Recovery
Primary: Recovery of Ability to Swallow After Neostigmine/Glycopyrrolate Antagonism of Rocuronium Paralysis. — 16; 25; 10; 6 participants — p=0.11
Phase 4 N=189 Best Management of Muscle Relaxation- Objective Monitoring
Residual Paralysis, Post Anesthesia
Primary: Incidence of Postoperative Residual Neuromuscular Blockade at Time of Extubation — 0 Participants
Phase 4 N=260 Sugammadex vs Placebo to Prevent Residual Neuromuscular Block
General Surgery
Primary: Decreased Minute Ventilation (MV) — 20; 26 Participants
Phase 3 N=154 Study of Sugammadex Versus Usual Care on Incidence of Residual Blockade at Post Anesthesia Care Unit Admission (P07981)
Surgical Procedures, Elective
Primary: Incidence of Residual Neuromuscular Blockade (NMB) as Defined by a Train-of-Four (TOF) Ratio <0.9 at Post Anesthesia Care Unit (PACU) Entry — 0; 33 participants…
Phase 4 N=50 Postoperative Urinary Retention in Patients After Noncardiac Surgery and Reversal of Neuromuscular Block
Neuromuscular Blockade
Primary: Urine Residual in PACU — 219; 222 ml
Phase 3 N=62 Comparision of Different Dose of Neostigmine at Advanced Decurarization
Anesthesia
Primary: Mesure of the Train-of-four (TOF) — 3.8; 4.5; 11.5; 19 minute
Phase 2 N=49 Neuromuscular Blockade in Patients With Severe Renal Impairment
Neuromuscular Blockade · Renal Impairment
Primary: Time Until Complete Reversal of Neuromuscular Blockade — 14.8; 3.5 Minutes
N/A N=36 Emergence From Anesthesia in Anterior Temporal Lobectomy and Amygdalohippocampectomy Patients
Emergence From Anesthesia
Primary: Volumes of the Hippocampus, Thalamus and Amygdala — 3578; 3903; 3479; 3525 mm3
Phase 4 N=79 Use of Sugammadex for Reversal of Paralysis in Microlaryngoscopy
Microlaryngoscopy · Rigid Bronchoscopy
Primary: Time to Extubation After End of Procedure — 11.06; 10.36 Minutes
Phase 3 N=75 Recovery of Diaphragmatic Function After Neuromuscular Blockade and Sugammadex
Diaphragmatic Dysfunction · Muscle Weakness · Muscle Fatigue
Primary: Electric Activity of the Diaphragm (Microvolts) — 3.7; 4.5; 3.2; 2.9 microvolt
N/A N=117 Intraoperative Neuromuscular Blockade and Postoperative Atelectasis
Thoracic Surgery · One-lung Ventilation
Primary: Atelectasis Area on Chest CT — 1.32; 1.41 percentage of atelectasis volume
N/A N=120 Treatment of Critical Illness Polyneuromyopathy
Acute Respiratory Failure
Primary: The Primary Outcome Variable for This Study Will be the Short Form of the Continuous Scale Physical Functional Performance Test (CS-PFP) Called the PFP-10 — 19.0; 20.9…
Phase 4 N=40 Speed of Recovery of Reversal of Neuromuscular Blockade in Geriatric Patients Undergoing Spine Surgery
Spine Surgery
Primary: Difference in Time of Neuromuscular Recovery From a Neuromuscular Moderate Blockade — 3.9; 26.29 Minutes
N/A N=55 Post- Surgery Recovery: Nerve Blocks w/ Sedation vs. Nerve Block w/ Either Sedation/Gen. Anesthesia
Nausea · Emesis
Primary: Number of Participants With Nausea 1 Hour After Post-anesthesia Care Unit (PACU) Admission — 1; 0; 1; 14 Participants
Phase 4 N=21 Time to Post-Anesthesia Neurological Evaluation With Three Different Anesthetic Techniques
Carotid Artery Stenosis
Primary: Time to First Neurological Exam — 9; 7; 7 Minutes
Phase 4 N=128 The Laparotomy Study
Gastrointestinal Cancer
Primary: Surgical Rating Score — 4; 4.75 units on a scale — p=<0.05
Phase 4 N=100 Effect of Neuromuscular Reversal With Sugammadex on Postoperative Recovery Profile
Postoperative Respiratory Condition
Primary: Mean Lowest Saturation — 96.8; 93.3 percentage of oxygen saturation
N/A N=22 Improved Patient Recovery After Anesthesia With Hypercapnia Hyperpnoea
Hypercapnia
Primary: Recovery From Anesthesia — 53.0; 62.9 minutes — p=>0.05
Phase 4 N=84 Sugammadex Versus Neostigmine for Reversal of Neuromuscular Blockade at the End of Kidney Transplantation Surgery
Kidney Transplant; Complications · Postoperative Residual Curarization · Postoperative Residual Weakness
Primary: Number of Patients With Hypoventilation in Post-anesthesia Care Unit (PACU) — 22; 23 Participants
Phase 4 N=102 Deep vs Moderate Neuromuscular Blockade With Rocuronium in Patients Undergoing Endolaryngeal Procedures
Laryngoscopic Surgical Procedures
Primary: Proportion of Patients Who Have a Clinically Acceptable Surgical Conditions — 0.89; 1 Proportion of patients
Phase 4 N=90 Optimizing Post-operative Recovery in Bariatric Patients With Obstructive Sleep Apnea Undergoing Outpatient Surgery: A Comparison of Sugammadex and Neostigmine
Anesthesia
Primary: Time to PACU Discharge — 123; 125 minutes
Phase 4 N=350 Deep Neuromuscular Block for Laparoscopic Surgery
Laparoscopy · Anesthesia Recovery Period
Primary: Percentage of Patients Recovered Cognitively at 1 Week — 91.8; 92.9 percentage of patients recovered
Phase 4 N=235 Postoperative Urinary Retention After Reversal of Neuromuscular Block by Neostigmine Versus Sugammadex
Urinary Retention Postoperative · Laparoscopic Cholecystectomy · Neuromuscular Blockade
Primary: Number of Participants With Postoperative Urinary Retention (POUR) of Sugammadex and Neostigmine Groups — 20; 6 Participants
N/A N=39 Bupivacaine Versus Ropivacaine on Diaphragmatic Motility and Ventilatory Function
Paresis
Primary: Forced Expiratory Volume at 1 Second (% Change From Baseline) — -22.4; -29.4 percentage of change from baseline