N/A N=304 Testing a Community-Friendly Risk Reduction Intervention for Injection Drug Users
HIV · Opioid Dependence
Primary: Demonstrated Drug Risk Reduction Skills (0-100%) — 40.60; 42.75 Percentage of correct steps
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=59 Reducing HIV Risk Among Episodic Substance Using Men Who Have Sex With Men (SUMSM)
HIV Infections · Episodic Substance Use
Primary: Total Unprotected Anal Intercourse Events (Exclusive of Those Events With a Primary HIV-negative Partner) — 4.23; 3.91; 3.41; 2.05 Self reported events in past 3 months
N/A N=146 Prevention of Adolescent Risky Behaviors: Neural Markers of Intervention Effects
Risk-Taking · Adolescent Behavior
Primary: Changes in Emotional Regulation — 54.43; 52.02; 54.47; 60.77 T Score — p=0.003
N/A N=1,635 Breast Cancer Risk Reduction: A Patient Doctor Intervention
Breast Cancer
Primary: Knowledge of Breast Cancer Risk Factors — 48.9; 56.4 units on a scale
N/A N=72 Prevention of Alcohol-related Sexual Revictimization in College
Sexual Assault
Primary: Days Per Month Hazardous Drinking — 7.54; 10.40; 1.97; 1.53 Days per Month Hazardous Drinking — p=<0.99
N/A N=511 Sustainable HIV Risk Reduction Strategies for Probationers
Health Behavior
Primary: HIV Knowledge Confidence — 42.9; 40.5 units on a scale — p=<.001
Phase 2 N=584 Behavioral Intervention to Reduce Sexual and Injection Risks Among Female Sex Workers Who Also Inject Drugs in Mexico
HIV · HIV Infections
Primary: Combined HIV/STI 12-month Incidence Rates of HIV, Syphilis, Chlamydia, Gonorrhea and Trichomonas Vaginalis. — 65.02; 67.66; 35.02; 54.04 incidence density per 100 person…
Phase 3 N=1,010 Reducing Sexual Risk Behaviors and Improving Health for People at a Sexually Transmitted Infection Clinic
HIV · Sexually Transmitted Diseases · HIV Infections
Primary: Number of Sexual Partners, 3 Months Post Intervention — 2.19; 2.04; 2.14; 2.13 number of partners
N/A N=365 Protective Behavioral Strategies and Brief Alcohol Interventions
Alcohol Consumption
Primary: Drinks Per Week — 12.55; 9.57; 13.74 drinks per week
N/A N=54 Behavioral Intervention in Reducing Indoor Tanning
Healthy Subject
Primary: Number of Prior 2-Month Indoor Tanning Sessions Reported by Participants on a Follow-up Survey — 11.5; 7.9 indoor tanning sessions
N/A N=460 Alcohol, Marijuana, and Risky Sex: Group Interventions With Detained Adolescents
Risk Reduction Behavior · Health Behavior · Sexual Behavior
Primary: Number of Participants With Risky Sexual Behavior Measured for 1 Year — 143; 155; 162 Participants
N/A N=1,317 Teen Video Study to Reduce Risky Driving and Sexual Behavior in Adolescents
Pregnancy · Sexually Transmitted Infections · Automobile Accidents
Primary: Perceived Self-efficacy for Condom Use — 13.00; 12.48 summation score
N/A N=1,181 Men Together Making a Difference: Reducing HIV/STD Risk Behavior Among South African Men
Human Immunodeficiency Virus Infection · Sexually Transmitted Diseases
Primary: Self-reported Consistent Condom Use During Vaginal Intercourse in the Past 3 Months — 121; 103; 125; 93 Participants — p=.008
N/A N=127 Cocaine Use Reduction and Health
Cocaine Use Disorder
Primary: Endothelin-1 Levels — 2.15; 2.063; 1.956 pg/ml
N/A N=881 Efficacy of a Web-based Sexual Violence Risk Reduction Program for Female College Students
Sexual Violence
Primary: Change From Baseline in Sexual Violence Victimization at 6-months Follow-up — 5.64; 5.68; 5.52; 8.15 score on a scale — p=.0002
N/A N=372 Brief Interventions in the Emergency Department for Alcohol and HIV/Sexual Risk
Alcohol Consumption · Unsafe Sex
Primary: Number of Alcoholic Drinks Consumed Per Week — 9.1; 16.5 Drinks per week
N/A N=3,570 A School-Based Intervention to Reduce Lyme Disease
Lyme Disease
Primary: The Incidence of Lyme Disease Among Children and Families Living in an Endemic Area Using an Educational Intervention — 1; 1 Number of cases incident Lyme disease
N/A N=108 Protecting Allies in Risky Situations
Sexual Assault · College Drinking · Behavioral Changes
Primary: Change in Readiness to Intervene on the Readiness Ruler — 7.22; 7.44; 8.60; 7.29 score on a scale
Phase 1 N=41 Bupropion For Reducing High-Risk Behaviors in Depressed Men Who Have Sex With Men (MSM)
HIV Infections · Depression
Primary: The Number of Sexual Partners in Unprotected Anal Intercourse Reported at 6 Months Minus the Number Reported at Enrollment. — -2.5; -4 Sexual partners — p=0.9
N/A N=196 Prevention and Risk: Treatment With a New Emphasis on Relationships
Adherence, Medication · Risk Reduction · Drug Use
Primary: Illicit Drug Use Days — 1.49; .80; 1.16; 0.83 days — p=.433
N/A N=2,622 Effectiveness of an Online Prevention Program in Reducing the Risk of STD Infection in Young Adults
HIV Infections · Sexually Transmitted Diseases
Primary: Efficacy of Internet-based Program for Increasing Condom Use With Non-main Sex Partners — .68; .56 percentage of sex acts protected by cond
N/A N=60 Understanding and Reducing HIV Risk Behavior and Substance Use Among Self-identified Bisexual Adolescent Men
HIV/AIDS · Substance Use · Bisexuality
Primary: Retention — 25; 26 Participants
N/A N=20 Investigating Fear Of Recurrence as a Modifiable Mechanism of Behavior Change
Acute Coronary Syndrome · Fear · Medication Adherence
Primary: Change in Total Score for Concerns About Recurrence Scale [Adapted for Acute Coronary Syndrome] — -5.40; -2.86 change in score on a scale — p=0.698
Phase 3 N=8,231 "REDUCE" - A Clinical Research Study To Reduce The Incidence Of Prostate Cancer In Men Who Are At Increased Risk
Neoplasms, Prostate
Primary: Number of Participants With Biopsy-detectable Prostate Cancer at Years 2 and 4 (Crude Rate Approach) — 578; 435; 280; 224 participants — p=<0.0001
N/A N=222 Reducing HIV Risk Among Adolescents: Evaluating Project HEART
HIV · Sexually Transmitted Diseases
Primary: 6-item Self-report of Program Acceptability — 84; 94; 101; 60 Participants
N/A N=400 Brief Intervention for Rural Women at High Risk for HIV/HCV
Acquired Immune Deficiency Syndrome Virus · Hepatitis C · Drug Abuse
Primary: Number of Participants Having Unprotected Casual Sex — 27; 25 Participants
N/A N=136 Reduced Nicotine Content Cigarettes and Tobacco Switching Behaviors
Tobacco Addiction · Dual Tobacco Use
Primary: Number of Days Using Alternative Products — 14; 26; 20 Number of days
N/A N=226 Reducing HIV Risk Among Adolescents: Evaluating HEART for Teens
HIV Infections · Sexually Transmitted Diseases
Primary: Acceptability — 88; 83 Participants
N/A N=979 Change the Cycle: An RCT to Prevent Injection Initiation
Substance Abuse, Intravenous · HIV · Heroin Dependence
Primary: People Initiated Into Injection Drug Use — 2.05; 3.26 People initiated — p=0.35
Early Phase 1 N=21 Reduced Nicotine Cigarette Purchasing Decisions
Tobacco Use Disorder
Primary: Demand Intensity — 6.48; 8.10; 7.81; 6.48 cigarettes