N/A N=148 Investigation of Sacroiliac Fusion Treatment (INSITE)
Degenerative Sacroiliitis · Sacroiliac Joint Disruption
Primary: Subject Success — 84; 12 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=194 Sacroiliac Joint Fusion With iFuse Implant System (SIFI)
Degenerative Sacroiliitis · Sacroiliac Joint Disruption
Primary: Subject Success — 80.5 percentage of participants
N/A N=30 Effectiveness of the Compression Belt for Patients With Sacroiliac Joint Pain
Low Back Pain
Primary: Oswestry Low Back Pain Questionnaire — 26.00; 24.40; 17.20; 14.67 units on a scale
N/A N=60 Sacroiliac (SI) Screws: The Effect of SI Screw Removal on Patient-Reported Pain and Functional Outcomes
Sacroiliac Joint · Pain · Pelvis
Primary: Post-operative Pain Within 6 Months After Iliosacral Screw Removal Using the Brief Pain Inventory (BPI) — 3.7; 4.7 units on a scale — p==0.57
N/A N=28 Comparing the Effects of Ultrasound Versus Fluoroscopy for Sacroiliac Joint Injections
Sacroiliitis
Primary: Difference in Minutes Between a Sacroiliac Joint Injection Done With Ultrasound vs Fluoroscopy — 9.471; 9.552 minutes
Phase 4 N=51 Effectiveness of Ultrasound Guided Platelet Rich Plasma Injections in the Sacroiliac Joint
Chronic Low Back Pain · Sacroiliitis · Sacroiliac; Backache
Primary: Numeric Rating Scale for Pain (NRS) — 1.08; 1.58; 1.69; 1.94 units on a scale
N/A N=33 Imaging Biomarkers in Crohn's Associated Spondyloarthritis
Crohn's Disease · Spondyloarthritis
Primary: Number of Participants With MRI Positivity- Global Assessment Positive — 4; 0 Participants
N/A N=9 Surgical Treatment of Pelvic Joint Instability in Patients With Severe Pelvic Girdle Pain After Pregnancy and Trauma
Pelvic Joint Instability · Pelvic Pain
Primary: Oswestry Disability Index (ODI) — 54; 37 units on a scale
Phase 4 N=30 Intestinal Inflammation in Ankylosing Spondylitis and the Effects of Adalimumab on Mucosal Healing
Spondyloarthritis · Enterocolitis
Primary: Change Lewis Score Index — -225 units on a scale
N/A N=62 Correction of Low Back Pain From Sacroiliac Malrotation With a Simple in Home Exercise
Sacroiliac Strain · Low Back Pain
Primary: Oswestry Low-back Pain Disability Questionnaire Score Change Baseline Minus 1 Month: Comparison Immediate Corrective Exercise or Pelvic Stabilization Belt V Delayed…
Phase 2 N=38 Spondylitis Trial of Apremilast for Better Rheumatic Therapy
Ankylosing Spondylitis
Primary: Changes of Apremilast in Patients With AS, Changes in BASDAI Score From Baseline — -0.77; -1.59 units on a scale — p=0.139
N/A N=63 Predictive Value of the Active Straight Leg Raise on the Efficacy of a SJB in Posterior PGP During Pregnancy
Pelvic Girdle Pain
Primary: Change From Baseline in Functioning on the Active Straight Leg Rise (ASLR) Scale at 4 Weeks. — 4.87; 2.92 score on a scale — p=<.001
N/A N=152 Assial - Anti Tnf Treatment in Ankylosing Spondylitis: an Observational Cohort Study in Italy
Ankylosing Spondylitis
Primary: Percentage of Participants With Unchanged First Line Anti-TNF Treatment Up to Month 18 — 85.42 percentage of participants
Phase 3 N=498 Study of the Efficacy and Safety of Secukinumab in Participants With Active Psoriatic Arthritis With Axial Skeleton Involvement
Axial Psoratic Arthritis
Primary: Percentage of Participants With Response to Treatment (300 mg AIN457) as Assessed by the ASAS20 Criteria at Week 12 — 66.3; 62.9; 31.2 percentage of participants…
N/A N=51 Trial Assessing Cooled Radiofrequency Denervation as a Treatment for Sacroiliac Joint Pain Using the Sinergy System
Other Acute Pain · Chronic Pain
Primary: Pain Status Change for Sacroiliac Joint Pain Intensity — -2.4; -0.8 units on a scale — p=0.035
N/A N=147 Differences in Bone Cell Activity Between Rheumatoid Arthritis and Ankylosing Spondylitis
Rheumatoid Arthritis · Bone Resorption · Ankylosing Spondylitis
Primary: Osteoclast Differentiation Ex-vivo — 8; 12; 11; 5 OC/mm2
N/A N=39 Clinical and Radiological Manifestations of Coxitis in Patients With Ankylosing Spondylitis Treated With Golimumab
Ankylosing Spondylitis · Coxitis
Primary: BASFI (Bath Ankylosing Spodylitis Functionality Index) at 12 Months of Follow-up — 1.0 units on a scale
Phase 3 N=158 Infliximab for Treatment of Axial Spondyloarthritis (P05336 AM1)
Ankylosing Spondylitis · Axial Spondyloarthritis
Primary: Number of Participants Achieving the Assessment in Ankylosing Spondylitis (ASAS) Partial Remission Criteria at Week 28 — 65; 18; 40; 33 Participants
Phase 3 N=204 Study of Efficacy and Safety of Secukinumab in Psoriatic Arthritis and Axial Spondyloarthritis Patients With Active Enthesitis Including One Achilles Tendon Site
Psoriatic Arthritis · Axial Spondyloarthritis · Enthesitis
Primary: Number (%) of Patients With Resolution of Achilles Tendon Enthesitis — 43; 32 Participants — p=0.136
Phase 3 N=64 Efficacy of Golimumab in Early Axial Spondyloarthritis in Relation to Gut Inflammation
Axial Spondyloarthritis
Primary: Proportion of Patients Achieving Sustained Clinical Remission — 34 Participants
Phase 3 N=371 16 Week Efficacy and 2 Year Long Term Safety and Efficacy of Secukinumab in Patients With Active Ankylosing Spondylitis
Ankylosing Spondylitis
Primary: Assessment of Responders for the SpondyloArthritis International Society / ASAS 20 Response — 59.7; 60.8; 28.7 % responders — p=<0.0001
Phase 4 N=566 Study Evaluating Etanercept and Sulphasalazine in Ankylosing Spondylitis
Ankylosing Spondylitis
Primary: Number of Patients Achieving Assessment in Ankylosing Spondylitis (ASAS 20) — 287; 99 participants — p=<0.001
N/A N=26 Prevalence of Inflammatory Bowel Disease in Patients With Perianal Disease
Inflammatory Bowel Disease · Perianal Fistula · Perianal Abscess
Primary: Prevalence of Inflammation as Diagnosed by Capsule Endoscopy — 6 participants
Phase 3 N=208 A Study of Golimumab in Participants With Active Ankylosing Spondylitis
Ankylosing Spondylitis
Primary: Percentage of Participants Who Achieved at Least 20 Percent Improvement From Baseline in the Assessment of SpondyloArthritis International Society (ASAS 20) at Week 16…
Phase 3 N=316 A Study of Ixekizumab (LY2439821) in TNF Inhibitor Experienced Participants With Radiographic Axial Spondyloarthritis
Spondyloarthritis
Primary: Percentage of Participants Achieving an Assessment of Spondyloarthritis International Society 40 (ASAS40) Response — 12.5; 25.4; 30.6 Percentage of participants — p=0.017
N/A N=259 MRE as a Screening Tool for axSpA in IBD
Axial Spondyloarthritis · Crohn Disease
Primary: The Sensitivity and Specificity of MRE as a Screening Tool for Axial Spondyloarthritis in Crohn's Disease — 0.88; 0.50; 0.78 Probability
N/A N=100 Sagittal Plane Shear Index for Planning Lumbar Stenosis Surgery
Lumbar Spinal Stenosis · Spondylolisthesis
Primary: Proportion of Surgical Plans Recorded Prior to the SPSI Report That Are Altered After Integration of SPSI Into the Surgical Planning — 47; 22; 6 Surgical plans
N/A N=47 Anchorsure Versus Capio for Sacrospinous Ligament Fixation
Postoperative Pain
Primary: Change in Buttock and Posterior Thigh Pain — -0.5; -0.2; -1.8; -1.5 score on a scale
N/A N=46 Reducing Post-Op Pain After Sacrospinous Ligament Colpopexy
Pain
Primary: Postoperative Gluteal Pain — 3.6; 4.0; 2.0; 2.0 units on a scale — p=0.83
Phase 4 N=211 Study to Examine the Clinical Efficacy and the Nonsteroidal Anti-inflammatory Drug (NSAID)-Sparing Effect of Secukinumab Over 16 Weeks in Patients With Ankylosing Spondylitis
Ankylosing Spondylitis
Primary: Proportion of Patients Who Achieved ASAS20 Response in the Pooled Secukinumab Group Compared With the Placebo Group at Week 12 — 72; 31 Participants — p=0.3512