N/A N=79 Patient Perception of Visual Distortions
Cataract · Astigmatism
Primary: Visual Distortion Symptoms — 0.89; 0.38; 0.64; 0.38 rating of visual distortion symptoms
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=48 Visual Restoration for Hemianopia
Stroke Induced Vision Loss · Hemianopia · Quadrantanopia
Primary: 24-2 Humphrey PMD Change From Baseline to 6-month Post-training Timepoint — 0.84; 0.10; 0.58; 0.12 decibels
N/A N=6 Feasibility Electrical Stimulation Study for Visual Hallucinations
Schizophrenia · Schizoaffective Disorder · Bipolar Disorder
Primary: Steady State Visual Evoked Potential (ssVEP) — 1.725; 1.160; 1.180; 1.005 microvolts — p=0.10
N/A N=4 Visuomotor Rehabilitation Training for Manual Task Deficits From Macular Scotomas
Scotoma, Central · Central Visual Impairment
Primary: Improvement in Eye-hand Coordination — 42.8; 45.4; 30.4; 71.0 Percentage
N/A N=22 Trial of Alternating Current Stimulation in Optic Neuropathy
Optic Nerve Diseases · Optic Nerve Injuries · Optic Neuropathies
Primary: Detection Accuracy (DA) Change in Percent Over Baseline Within Defective Visual Field Sectors — 24.75; 39.16 percent change
N/A N=36 A Multi-Center Study of Reading Rehabilitation in Macular Disease
Age Related Maculopathy · Retinal Degeneration
Primary: Sentence Reading — 58.9; 50.5; 86.2; 49.1 Words per Minute (wpm)
N/A N=40 Rod Sensitivity in Age-related Macular Degeneration (AMD) and Retinitis Pigmentosa (RP)
Retinitis Pigmentosa · AMD
Primary: Rod Sensitivity Within the Central Retina as Measured on the Nidek MP-3S — 7; 20 Participants — p=<0.05
Phase 4 N=54 Comparison of Visual Field Assessments Between Three Perimeters
Glaucoma
Primary: Total Acquisition Time (Both Eyes) — 4.44; 7.34; 7.71 minutes
N/A N=6 The Perceptual Experience of Argus II Users
Retinitis Pigmentosa
Primary: Number of Phosphenes Perceived — 1.09; 1.43; 1.46; 1.41 number of phosphenes — p=0.002
N/A N=5 Multisensory Rehabilitation of Hemianopia
Hemianopia
Primary: Number of Points Detected at Multiple Locations — 14.0; 94.9; 63.6; 95.4 Number of points
N/A N=33 Analysis of the Eye in Patients With Primary Open-Angle Glaucoma and a Visual Field Defect in One Eye
Glaucoma
Primary: Lamina Cribrosa (Boundaries of the Retinal Layers) Measurements — 264.3; 273.3; 276.2 micro-ohms
Phase 2 N=166 A Multi-Center, Double-Masked Evaluation of the Efficacy and Safety of CSF-1 in the Treatment of Presbyopia
Presbyopia
Primary: Number of Subjects With ≥ 3 Lines Gain in Near Best Distance Corrected Visual Acuity (BDCVA) (at 40 cm) — 10; 12; 10 Participants — p=0.8445
N/A N=24 Comparison of Multifocal Electroretinogram Assessment in Chronic Central Serous Chorioretinopathy (CSC) Between Laser Treatment Group and Photodynamic Therapy Group in Chronic Central Serous Chorioretinopathy
Central Serous Chorioretinopathy
Primary: Multifocal Electroretinogram Amplitudes — 28.4; 32.2; 29.7; 36.1 microvolts
N/A N=73 Clinical Trial of Peripheral Prism Glasses for Hemianopia
Homonymous Hemianopia
Primary: Overall Proportion Saying "Yes" to Real Prism Glasses — 39; 22 participants — p== 0.001
N/A N=135 A Pilot Study Evaluating Photobiomodulation Therapy for Diabetic Macular Edema
Diabetic Macular Edema
Primary: Change in Optical Coherence Tomography Central Subfield Thickness From Baseline to 4 Months — 13; 15 microns
Phase 2 N=320 A Study of NGM621 in Participants With Geographic Atrophy
Geographic Atrophy
Primary: The Rate of Change From Baseline in Geographic Atrophy (GA) Lesion Area — 2.243; 2.237; 2.393 mm^2 per year — p=0.4345
Phase 4 N=65 A Study of the Structure and Function of the Retina in Adult Patients With Refractory Complex Partial Seizures Treated With Vigabatrin (Sabril®)
Adult Refractory Complex Partial Seizures
Primary: Mean Change From Reference Value in Field Width as Measured by 30-2 SITA Fast in Field Sensitivity (Mean Deviation - MD in dB) — -0.28; -0.24; -0.14; -0.13 dB
N/A N=155 Eye Movements, Visual Perception and Attention
Vision
Primary: Average Performance in Visual Tasks — 74 percentage
N/A N=22 Optical Head-Mounted Display Technology for Low Vision Rehabilitation
Retinal Dystrophies · Healthy
Primary: Change in the Planimetric Area of Goldmann Visual Field With the Use of Head-mounted Display Technology Compared to Baseline (Measured in Degrees Squared) — 563.08…
Phase 3 N=241 Improving Function in Age-Related Macular Degeneration
Age-Related Macular Degeneration
Primary: Targeted Vision Function (TVF) — 2.18; 2.14 units on a scale — p=.47
N/A N=52 Cirrus HD-OCT Measurement of Area of Increased Light Penetration Under the Retinal Pigment Epithelium (RPE)
Age Related Macular Degeneration · Geographic Atrophy
Primary: Difference in mm Squared of Cirrus HD-OCT Automated Measurements of the Illumination Areaa Under the RPE to Expert Manual Measurement of Areas of Hypofluorescence…
Phase 2 N=22 Ranibizumab and Peripheral Scatter Laser in Patients With Diabetic Macular Edema and Peripheral Nonperfusion
Diabetic Macular Edema
Primary: Mean Change in Best Corrected Visual Acuity (BCVA), as Assessed by the Number of Letters Read Correctly on the ETDRS Eye Chart at a Starting Test Distance of 4 Meters…
N/A N=6 VR System for Cross-modal Rehabilitation of Hemianopia
Hemianopia, Homonymous · Hemianopsia, Homonymous
Primary: Humphrey Visual Field Perimetry — 108; 1272 visual angle degrees^2
N/A N=25 Metabolic Changes in the Activated Human Visual Cortex During Mild Hypoxia
Brain Hypoxia
Primary: Change in Glutamate Concentration During a Visual Stimulus Measured by fMRS at Normoxia — 4 percentage of concentration (micromol/g)
N/A N=98 SmartSystem Virtual Reality Headset Perimeter Versus Humphrey HFA-III Perimeter
Glaucoma
Primary: Visual Field Performance Metric #1 - Mean Deviation — -7.17; -6.88 decibels — p=0.297
N/A N=180 Variability in Perimetry Study
Glaucoma
Primary: Number of Subjects Progressing in Each Group Using Pointwise Linear Regression — 0; 0 participants — p=.21