30 closest matches · ranked by relevance
Pulmonary Disease, Chronic Obstructive
Primary: Internal Consistency (IC) of the Shortness of Breath With Daily Activities (SOBDA) Questionnaire in Participants With Chronic Obstructive Pulmonary Disease (COPD)…
COPD · Dyspnea
Primary: Average Distance During Modified 6 Minute Walk Test — 128.0; 129.9; 137.5; 121.3 meters — p=0.02
Chronic Obstructive Pulmonary Disease
Primary: Breathlessness — 0.68; 0.71; 0.34; 0.83 score on a scale
Pulmonary Disease, Chronic Obstructive
Primary: Change From Baseline in Intensity of Breathlessness Measured Using the Modified Borg Scale at the End of the 3 Minute (Min) Constant Speed Shuttle Test After 6 Weeks of…
COPD
Primary: Change in Chronic Respiratory Disease Questionnaire (CRQ)- Dyspnea Score — 0.68; 0.71; 0.34; 0.83 score on a scale
Advanced Cancers
Primary: Number of Participants Completing Study Intervention — 7; 10; 3; 5 Participants
Dyspnea · Pulmonary Complications · Unspecified Adult Solid Tumor, Protocol Specific
Primary: Dyspnea as Measured by Oxygen Cost Diagram (OCD) — 8.98; 9.32 units on a scale — p=0.080
Chronic Obstructive Pulmonary Disease
Primary: Intensity of Breathlessness — 80.8; 77.9 units on a scale
Lung Cancer
Primary: Modified Medical Research Council Dyspnea Scale (mMRCDS) — 1.88; 1.55 units on a scale — p=0.038
Dyspnea · Non-small Cell Lung Cancer · Small Cell Lung Cancer
Primary: Incidence of Grade 3 or Higher Hypotension, Acute Kidney Injury, Allergic Reaction, or Anaphylaxis, as Measured Using the National Cancer Institute Common Terminology…
COPD Exacerbation
Primary: Change in Exhaled Breath Metabolites — 3298 breath metabolites
Pulmonary Disease, Chronic Obstructive
Primary: Number of Participants With Any Adverse Events (AEs) and Serious AEs (SAEs) — 120; 27 Participants
COPD
Primary: Duration of Exercise Time on a Constant Work-rate Treadmill Test — 12.2; 12.5 change in number of minutes walked — p=0.94
Exercise-induced Bronchoconstriction (EIB)
Primary: Maximum Percent Fall in Forced Expiratory Volume in 1 Second (FEV1) After Exercise Challenge at 2 Hours Postdose — 15.35; 20.00 Percent fall in FEV1 — p=0.020
COPD
Primary: Virtual Education Module Adherence — 17 Participants
Anxiety
Primary: Episodic Anxiety Scale — 8.1; 9.0; 14.3 units on a scale
Chronic Obstructive Pulmonary Disease
Primary: Exercise Duration for Constant Work Rate Exercise Tests Under 4 Test Conditions — 6.3; 17.5; 11.4; 5.6 minutes — p=<0.05
Pulmonary Disease, Chronic Obstructive
Primary: Number of Participants With a Post-bronchodilator FEV1/FVC <=70% Versus Participants With a Postbronchodilator FEV1/FVC >70% — 308; 893 participants
Amyotrophic Lateral Sclerosis (ALS) · Neuromuscular Diseases
Primary: Percent Change in Maximal Inspiratory Pressure (MIP) — 0.3; -3.1; -4.8; -5.0 percentage change in MIP from baseline
Pulmonary Arterial Hypertension
Primary: Change From Baseline in Patient Global Impression of Severity (PGI-S) Score in Cohort A Participants at Approximately 30 Minutes of Previous Dose of Inhaled Treprostinil…
Asthma
Primary: Central and Peripheral Elastance — 391; 461; 587; 334 cmH2O/L
Adolescent Behavior · Asthma
Primary: Asthma-specific Quality of Life — 65.4; 65.1; 66.7; 67.4 score on a scale
Pulmonary Disease · COPD
Primary: Exercise Duration (Time Walked on the Constant Workrate Treadmill Test) — 15.2; 17.6 minutes — p=0.63
Occupational Exposure
Primary: Maximum Oxygen Consumption (VO2max) — 26.4 ml/kg/min
Chronic Obstructive Pulmonary Disease
Primary: Number of Participants With Adherence to Home Breathing Exercises — 10; 5 Participants
Pulmonary Disease, Chronic Obstructive
Primary: Change From Baseline in Inspiratory Capacity (IC) at Isotime — 0.0035; 0.07 liter — p=0.0087
Dyspnea
Primary: Number of Participants With Transient Dyspnea. — 23 Participants
Chronic Obstructive Pulmonary Disease · Acute Coronary Syndromes
Primary: COPD Diagnosis — 39 participants
Healthy · Dyspnea
Primary: Subject Rating of Breathing Discomfort (Dyspnea) — 20; 20; 16; 17 units on a scale — p=0.99
Asthma · Sleep Apnea
Primary: Asthma Control Test — 19.3; 19.8; 19.1; 19.6 units on a scale — p=0.8