N/A N=10 Blood Loss at the Time of First Trimester Surgical Abortion in Anticoagulated Women
Blood Loss
Primary: Volume of Intraoperative Blood Loss — 91.5; 52.2 milliliters
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=181 A Randomized Controlled Trial of Three Antibiotic Regimens for First Trimester Abortions
First Trimester Abortion
Primary: Nausea Scale — 8; 9; 6; 6 Participants
Phase 3 N=4 Comparing Buccal and Vaginal Misoprostol in Management of Early Pregnancy Loss
Spontaneous Abortion in First Trimester
Primary: Patient Enrollment — 2; 2 Participants
N/A N=251 Optimisation of the Management of Placental Delivery in Second Trimester Pregnancy Interruption
Placenta, Retained · Postpartum Hemorrhage
Primary: Placental Retention Rate — 26; 8; 24 participants — p=0.05
Phase 3 N=153 Misoprostol for Treatment of Fetal Death at 14-28 Weeks of Pregnancy
Intrauterine Fetal Demise
Primary: Successful Expulsion of Fetus and Placenta Within 48 Hours — 60; 47 participants — p=<0.05
Phase 4 N=250 Pain Control In First Trimester Medical Abortion: A Randomized Trial
Pain
Primary: 11-point Visual Analog Scale for Pain — 7.1; 7.3 units on a scale
N/A N=50 The Use of Cell Free Fetal DNA in the Maternal Blood in the Evaluation of Intrauterine Fetal Demise and Miscarriage
Circulating Cell Free Fetal DNA · Intrauterine Fetal Demise · Miscarriage
Primary: The Presence or Absence of Cell Free Fetal DNA in Maternal Blood in the Setting of a Failed Pregnancy. — 50 percentage of participants
N/A N=135 Fetal Fibronectin as a Predictor of Successful Induction of Mid-trimester Abortion
Medical; Abortion, Fetus
Primary: Cervicovaginal Fetal Fibronectin Level — 39.4 nanogram per milliliter
Phase 4 N=30 Simultaneous Mifepristone and Misoprostol Versus Misoprostol Alone for Induction of Labor of Nonviable Second Trimester Pregnancy: a Pilot Randomized Controlled Trial
Abortion, Second Trimester · PPROM · Rupture, Spontaneous
Primary: Delivery Within 12 Hours — 5; 5 Participants
Phase 2 N=69 Cabergoline for Lactation Inhibition After Early Second-Trimester Abortion or Pregnancy Loss
Lactation Suppressed
Primary: Number of Participants Reporting Breast Pain — 16; 30 Participants
N/A N=634 Transabdominal and Transvaginal Sonography in Medical Abortion
Abortion Early
Primary: Percentage of Subjects in Each Ultrasound Group With Additional Testing — 63; 14 Participants
N/A N=500 Study of the Sensitivity of Manual vs Electric Aspiration to Detect Completed Early Abortion
Induced Abortion
Primary: Accurate Confirmation of Completed Abortion — 182; 164 participants — p=.13
Phase 2 N=3 Ulipristal Acetate for Use in Early Pregnancy Loss
Missed Abortion · Anembryonic Pregnancy · Non-Viable Pregnancy
Primary: Percentage of Participants Recruited to Study Protocol — 37.5 percentage of participants
Phase 4 N=121 Hydrocodone For Pain Control in First Trimester Surgical Abortion
Pain
Primary: Patient Perception of Pain — 65.7; 63.1 mm
N/A N=50 Mifepristone Versus Laminaria Insertion for Cervical Preparation Prior to Surgical Abortion at 14-16 Weeks
Abortion
Primary: Time for Completion of Procedure — 8.0; 9.87 Minutes — p=0.05
N/A N=30 Virtual Reality Experience in First Trimester D&C
First Trimester Abortion · Virtual Reality
Primary: Number of Participants Able to Use VR Device Throughout the Entire Duration of First Trimester Surgical Abortion. — 6 participants
Phase 4 N=100 Same-Day Mifepristone-Misoprostol Compared to Misoprostol Only for Surgical Abortion Cervical Preparation
Induced Abortion
Primary: Initial Cervical Dilation — 11.7; 10.9 mm
Phase 4 N=124 Evaluation of Oral Midazolam in First-trimester Surgical Abortions
Pain · Anxiety · Nausea
Primary: Subject Perception of Pain and Anxiety During Uterine Aspiration — 74.3; 70.1; 68.2; 60.9 mm
N/A N=60 Transvaginal Versus Transabdominal Digoxin Prior to Second-trimester Abortion
Abortion, Induced
Primary: Patient Discomfort With Digoxin Injection (Pain Score) — 2.21; 1.88 Units on a scale — p=0.36
N/A N=349 Walking and Dietary Modification for Recurrent Early Miscarriages
Recurrent Miscarriage
Primary: Take-home Baby Rate — 152; 83 babies
N/A N=109 Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Control During First Trimester Abortion
Abortion in First Trimester
Primary: Aspiration Pain — 73; 66 units on a scale
N/A N=51 The Role of a Semi-Quantitative Urine Pregnancy Test and Pregnancy Questionnaire After Uterine Evacuation for Undesired Pregnancy of Uncertain Location
Follow-up After Uterine Evacuation
Primary: Number of Women in Each Group Who Require a Return Visit to the Clinic for a Serum hCG Measurement, Ultrasound or Clinical Examination at One Week to Confirm Complete…
Phase 4 N=211 Misoprostol 400 µg Versus 200 µg for Cervical Ripening in 1st Trimester Miscarriage
Miscarriage in First Trimester
Primary: Number of Participants Who Required Cervix Dilation at Initiation of the Manual Vacuum Aspiration — 4; 16; 102; 89 Participants — p=0.025
N/A N=128 Early Anatomy Scan for Evaluation of Obese Pregnant Women (EASE-O)
Obesity
Primary: Completion Rate for First Trimester Scans — 66 percent
N/A N=50 Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 Weeks
Abortion, Induced
Primary: Procedure Time — 10.9; 11.8 minutes
N/A N=120 Insertion of an Intrauterine Device (IUD) After Medical Abortion
Intrauterine Device Expulsion · Medical Abortion · Induced Abortion
Primary: Percentage of Women With Expulsion of an Intrauterine Device (IUD) Placed After Medical Abortion. — 4 percentage of participants
Phase 3 N=50 Paracervical Block in First Trimester Surgical Abortions
Pain · Surgical Abortion
Primary: Level of Pain During Specific Time Intervals Throughout D&C Procedure. — 52.2; 51.7; 33.6; 32.7 mm — p=0.94
Phase 3 N=300 Comparative Effectiveness of Pregnancy Failure Management Regimens
Spontaneous Abortion
Primary: Gestational Sac Expulsion With One Treatment Dose on Day 3 (Visit 2) and no Need for Additional Medical or Surgical Intervention Within 30 Days of Treatment. — 100; 124…
N/A N=80 Lidocaine and Pain Management in First Trimester Abortions
Pain
Primary: The Effects of an Intrauterine Lidocaine Infusion to Standard Paracervical Block on Decreasing Patient Pain Measured by Visual Analog Scale in First Trimester Abortions…
N/A N=102 Iron Parameters in Non-anemic First Trimester Gravidas
Iron Deficiency (Without Anemia) · Pregnancy
Primary: Percent of Non-anemic Patients With Iron Deficiency Stratified by Gravidity — 9; 3; 6; 38 Participants