N/A N=400 Talk Therapy by Phone to Promote Treatment for Alcohol Problems
Alcohol Use Disorder · Alcohol Abuse
Primary: Average Drinks Per Drinking Day — 5.5; 5.4 drinks per occasion — p=0.746
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=100 Supportive and Supportive-Expressive Treatment for Depression
Major Depressive Disorder
Primary: Hamilton Rating Scale for Depression (HRSD) — 12.32; 12.06; 20.20; 20.08 units on a scale — p=.016
Phase 4 N=700 Sequenced Treatment Effectiveness for Posttraumatic Stress
PTSD
Primary: PTSD Symptoms — 39.3; 38.6; 40.5 units on a scale
N/A N=243 Comparing Group Therapies for Veterans With Depression and PTSD
Major Depressive Disorder · Posttraumatic Stress Disorder
Primary: Depression Anxiety Stress Scale (DASS-Depression) — 10.6; 11.0; 8.8; 8.1 units on a scale — p=.025
Phase 3 N=500 Adaptive Treatment for Alcohol and Cocaine Dependence
Substance Use Disorders
Primary: Treatment Engagement — 3.92; 3.50 treatment days — p=0.11
Phase 3 N=201 Evaluating Improvement Strategies in Addiction Treatment
Addiction
Primary: Change in Average Waiting Time From First Contact to Treatment — .253; 4.610; 4.723; 3.520 Change in days
N/A N=39 Optimizing Treatment Response in VA Specialized Intensive/Inpatient PTSD Programs
PTSD
Primary: Change in PTSD Symptoms — -23.86; -19.51 score on a scale
N/A N=115 Comparative Effectiveness of Two Treatments for Veterans With PTSD
Posttraumatic Stress Disorder
Primary: Change in Clinician Administered PTSD Scale (CAPS-5) — 36.3; 34.8; 1.52; 27.8 score on a scale — p=0.28
N/A N=30 Engage Psychotherapy to Promote Connectedness in Caregivers
Loneliness · Social Isolation · Caregiver Burnout
Primary: Loneliness — 48.76; 44.44 units on a scale
N/A N=300 Treatment, Pain, and Opioids
Chronic Pain
Primary: Medical Record Review and Treatment Utilization Form — 19; 17 Participants — p=.6469
N/A N=304 Comparing Individual Therapies for Veterans With Depression, PTSD, and Panic Disorder
Major Depressive Disorder · Posttraumatic Stress Disorder · Panic Disorder and Agoraphobia
Primary: PTSD Checklist for DSM-5 (PCL-5) — 48.0; 46.37; 42.44; 36.95 score on a scale
N/A N=465 Improving Transitional Care Experiences in Mental Health
Standard Treatment Versus Engagement Focused Treatment
Primary: Subjective Quality of Life — 3.9; 3.8; 4.3; 4.0 units on a scale
N/A N=323 Comparison of Treatment for Hoarding Disorder
Hoarding Disorder
Primary: Saving Inventory-Revised (SI-R) — 64.5; 66.4; 45.9; 47.8 units on a scale — p=0.04
N/A N=95 Treatment Engagement With Technology-assisted Treatment
Alcoholism · Substance-related Disorders · Mentally Ill Chemical Abuse
Primary: Acceptability of Treatment Based on Survey Questionnaire Completed by Participants — 8.78; 8.23 score on a scale
N/A N=169 Brief Treatment for Posttraumatic Stress Disorder
PTSD
Primary: Clinician Administered PTSD Scale, 5 (CAPS-5) — 31.55; 25.12; 29.59; 25.41 score on a scale
N/A N=12 Facilitating Engagement in Evidence-Based Treatment for Early Psychosis
Psychotic Disorders
Primary: Change in Decisional Conflict Scale — 0.55 score on a scale — p=.95
N/A N=60 Tailored Response to Psychiatric Comorbidity to Improve HIV Care Engagement in the United States
HIV/AIDS · Depression · Anxiety
Primary: Feasibility of Recruitment — 92 participants
N/A N=124 Adolescents' Well-being in Community-based Treatment Versus Residential Treatment
Adolescent Well-Being · Mental Disorders, Severe
Primary: Average Z-score From Participant Self Report on Domains in the Clinical Scale of the Treatment Outcome Package (TOP-CS) at Study Intervention Endpoint — 0.42; 0.63 Z-score
N/A N=299 Building Recovery By Improving Goals, Habits, and Thoughts
Depression · Substance Use
Primary: Depressive Symptoms as Measured by the Beck Depression Inventory II — 14.83; 21.82 BDI-II score
N/A N=329 Effectiveness of Peer-Delivered Trauma-Specific Treatment
Post-Traumatic Stress Disorder · Substance Use Disorders
Primary: Change in Post-traumatic Stress Disorder Symptoms — 47.2; 48.2; 43.9; 44.7 Score on a Scale — p=0.01
N/A N=145 Integrated Treatment for Adolescents With ADHD
ADHD · Substance Use Disorders
Primary: Change From Baseline in Symptoms: ADHD Symptoms (Inattention, Hyperactivity/Impulsivity) and Comorbid Problems (Conduct and Mood Problems, Substance Use). — 6.42; 6.90…
N/A N=330 The Use of a Novel Peer Education Program for Improving PTSD Treatment Engagement Among Veterans
PTSD · Posttraumatic Stress Disorder
Primary: PTSD Treatment Engagement (Yes/no) — 137; 132 Participants
N/A N=326 Engaging Patients With Mental Disorders From the ED in Outpatient Care
Mental Disorder
Primary: Number of Participants Attending at Least One Outpatient Visit — 85; 70 Participants
Phase 2 N=270 Evaluation of Treatments for Homeless Youths
Substance Abuse
Primary: Substance Use — 45.67; 53.60; 49.38 percent days of drug use
N/A N=183 Integrated vs Sequential Treatment for PTSD and Addiction
PTSD · Substance Addiction
Primary: PTSD Symptoms — 55.5; 54.1 units on a scale
N/A N=142 PracticeGround: Transforming Training and Delivery of Mental Health EBPs
Depression · Insomnia · Suicide
Primary: Depression, Anxiety, and Stress Scale (DASS) — 1.55; 1.68; 1.32; 1.4 score on a scale — p=.734
N/A N=19 Increasing Treatment Seeking Among Suicidal Veterans Calling the Crisis Line
Suicide
Primary: Change in Treatment Engagement (Number of Participants Entering Treatment) — 4; 4 Participants
N/A N=65 Reward Function and Therapy for Late-Life Depression
Major Depressive Disorder
Primary: Change in Late Positive Potential to Rewarding Stimuli — 0.80; 0.07 microvolts — p=.08
N/A N=81 Behavioral Activation for PTSD/Depression Treatment in OIF/OEF Veterans
Posttraumatic Stress Disorder · Depression
Primary: Clinician Administered PTSD Scale (CAPS-IV) — 75.9; 82.0; 54.4; 70.1 units on a scale
Phase 3 N=480 Brief Strategic Family Therapy for Adolescent Drug Abusers
Substance Abuse
Primary: Main Study, Adolescent Drug Use — 3; 3 days of drug use 28 days prior baseline — p=.27