N/A N=91 Cortisol Suppression and Startle Responses in Posttraumatic Stress Disorder (PTSD)
Post Traumatic Stress Disorder
Primary: Mean Baseline Startle Magnitude During Fear Conditioning — 48.401; 56.595; 115.778; 57.684 microvolts
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=28 Resolving Psychological Stress
Post-Traumatic Stress Disorder · Alcohol Use Disorder
Primary: PTSD Symptoms Using PTSD Checklist-5 (PCL-5) at Baseline and 15 Days — 33.2; 36.6; 31.2; 28.2 units on a scale — p=0.322
N/A N=606 Stress, Sex, and the Generalization of Fear
Psychological Stress
Primary: Fear-potentiated Startle Responses to the CS+ and CS- During Acquisition — 52.059; 19.162; 44.388; 9.732 Fear-potentiated startle (microvolts) — p=0.453
Phase 3 N=80 Post Traumatic Stress Disorder (PTSD) Hyperarousal Symptoms Treated With Physiological Stress Management
Stress Disorders, Post-Traumatic
Primary: Change Scores for Criteria D Items on the CAPS Structured Clinical Interview — -1.20; -6.27 units on a scale — p=.27
N/A N=119 Stress Response in Opioid Use Disorder
Opioid-use Disorder
Primary: Change in Negative Affect — 1.67; 1.25; 3.60 scores on a scale
N/A N=1,418 Effects of Arousal and Stress in Anxiety
Healthy Volunteers
Primary: Go Correct Hits Followed by Button Press — 90.9; 91.6 Percentage of correct responses
N/A N=139 Prevention of Post-traumatic Stress Disorder by Telephone Based Cognitive Behavioral Therapy
Stress Disorder - Post-traumatic (Acute)
Primary: Severity of PTSD Symptoms — 43.4; 43.9 CAPS total Score at treatment end — p=0.927
N/A N=124 Cognitive Behavioral Treatments for Post-traumatic Stress Disorder (PTSD) Sleep Disturbance
Post-traumatic Stress Disorder
Primary: Weekly Number of Nightmares — 3.95; 3.88; 3.28; 3.47 weekly nightmares
N/A N=112 The Effect of Reducing Posttraumatic Stress Disorder Symptoms on Cardiovascular Risk
PTSD
Primary: Change From Baseline to Post-Intervention in 24-hour Heart Rate Variability (HRV) Estimated From the Standard Deviation of the Interbeat Interval of Normal Sinus Beats…
N/A N=60 Implementing a Skills Training Evidence-Based Treatment for Posttraumatic Stress Disorder in Primary Care
Posttraumatic Stress Disorder
Primary: Posttraumatic Stress Disorder Symptoms Measured by PTSD Checklist for DSM-5 (PCL-5) — 61.48; 58.28; 39.12; 36.30 score on a scale
N/A N=88 Post-traumatic Stress Disorder (PTSD) Symptoms in Later Life
Post Traumatic Stress Disorder
Primary: The Trauma History Questionnaire (THQ; Green, 1996) — 5.93; 0.76; 3.81; 0.97 score on a scale
Phase 4 N=106 Veteran Stress and Learning Study
Stress Disorders, Posttraumatic
Primary: Proportion of Maximum Skin Conductance Response (SCR) in Microsiemens (µS) — .0325522; .0245775; -.0181339; .1233174 proportion of max SCR (µS) — p==.66
N/A N=120 Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial
Post-traumatic Stress Disorder · Alcohol Abuse · Alcohol Dependence
Primary: Number of Patients With High Levels of Adolescent PTSD Symptoms — 9; 12; 11; 12 Participants — p=0.71
N/A N=170 Stressor-evoked Brain and Cardiovascular Responses to Acute Psychological Stress
Acute Psychological Stress
Primary: Stressor-evoked Oxygen Consumption in mL/(kg·Min) (Stress - Baseline) — 0.265; 0.287 mL/(kg·min)
N/A N=25 DoD PTSD November 13 - Information Processing Modification in the Treatment of PTSD
Stress Disorders, Post-Traumatic
Primary: Post-Traumatic Stress Disorder Checklist-Military Version (PCL-M) — 63.08; 61.71; 42.83; 51.65 units on a scale
Phase 2 N=245 Prevention of Post Sexual Assault Stress
Drug Use · Drug Abuse · Posttraumatic Stress Disorder
Primary: Drug Abuse Screening Test (DAST-10) — 1.97; 2.03; 1.18 units on a scale — p=.24
Phase 4 N=84 Stress & Premenstrual Symptoms Study
PMDD · Stress · Mood
Primary: Acoustic Startle Response (ASR) Magnitude Based on Menstrual Cycle Phase — 54.2; 53.7; 56.4; 53.3 t score — p=0.139
N/A N=134 PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness)
Post Traumatic Stress Disorder · Schizophrenia · Schizoaffective Disorder
Primary: Posttraumatic Stress Disorder (PTSD) Checklist (PCL) — 66.94; 66.33; 51.20; 60.60 score on a scale
N/A N=10 Network Dysregulation Among Individuals With Comorbid Tinnitus and PTSD
Stress Disorders, Post-Traumatic · Tinnitus
Primary: Change in Score on Clinician Administered PTSD Scale for the DSM-5 (CAPS-5) — 33.10; 16.13 score on a scale — p=0.01
N/A N=82 Treatment of Posttraumatic Stress Disorder in Kosovar High School Students Using Mind-Body Skills Groups
Stress Disorders, Post-traumatic
Primary: Harvard Trauma Questionnaire — 2.5; 2.5; 2.0; 2.4 units on a scale
N/A N=85 Breathing Meditation Intervention for Post Traumatic Stress Disorder
Stress Disorders, Post-Traumatic
Primary: Change in PTSD Checklist (PCL) — -5.6; -6.8; -4.8; -6.8 score on a scale
N/A N=169 Brief Treatment for Posttraumatic Stress Disorder
PTSD
Primary: Clinician Administered PTSD Scale, 5 (CAPS-5) — 31.55; 25.12; 29.59; 25.41 score on a scale
N/A N=53 Stress in Inflammatory Bowel Disease
Inflammatory Bowel Diseases · Psychological
Primary: Retention Rate — 23; 25; 19; 22 Participants
Phase 2 N=404 Violence and Stress Assessment (ViStA) Project to Improve Post Traumatic Stress Disorder Management in Primary Care
Stress Disorders, Post-Traumatic
Primary: PTSD Symptoms — 71.1; 71.0 CAPS scores — p=0.97
N/A N=77 Stress, Emotion Regulation, and Alcohol in Women Veterans
Alcohol Use Disorder · Post Traumatic Stress Disorder
Primary: Change in Alcohol Craving During Experimental Sessions — 2.87; 2.97; 3.18; 3.22 Units on a Scale — p=.94
Phase 4 N=1,004 Primary Care Intervention Strategy for Anxiety Disorders
Post-traumatic Stress Disorder · Generalized Anxiety Disorder · Panic Disorder
Primary: BSI-12 (Anxiety and Somatization Subscales) — 325; 258 number of responders
Phase 4 N=40 Depression, Epinephrine, and Platelet Function
Major Depressive Disorder
Primary: Response of Participants, Defined by Change in the 21-item Hamilton Depression Rating Scale (HDRS) From Baseline to Week8 — 5; 9; 2; 4 participants — p=.918
N/A N=93 Recovery After Stress Toolkit (RESET) Study
Post-Traumatic Stress Disorder in Children · Post-Traumatic Stress Disorder in Adolescence
Primary: Child PTSD Symptom Scale (CPSS) — 10.4; 14 Score on a scale
N/A N=199 Caregiver Self-Management of Stress
Caregiver Distress · Job Stress
Primary: 10-item Kessler Psychological Distress Scale (K10) — 23.38; 23.79 score on a scale — p=0.513
N/A N=64 Neurobiological Similarities of Tinnitus and PTSD
Posttraumatic Stress Disorder · Tinnitus
Primary: Resting-State Functional MRI — 0.55; 0.35; 0.29; 0.59 Z-Score — p=0.01