N/A N=30 Analysis of the Effect of Antimicrobial Soap on Bacterial Survival
Survival of Bacteria on Skin After Using Different Soaps
Primary: Relative GAS Survival — 100; 75; 90 percentage overall bacterial abundance
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=10 Effect of Surfactants on the Skin Microbiome
Healthy Skin
Primary: Relative 16S Abundance - Control Soap — 100; 74; 84; 100 Percentage of Baseline
N/A N=10 Effects of Surfactants on the Innate Immune System
Healthy
Primary: Normalized LL-37 Expression — 100 percentage of baseline
Phase 4 N=50 BPO vs Hibiclens Soap for Surgical Preparation
Propionibacterium Acnes
Primary: Number of Patients With a Positive Propionibacteria Swabs on Day of Surgery After At-Home Washes With Benzoyl Peroxide or Chlorhexidine Gluconate — 25; 24; 14; 11…
Phase 3 N=1,388 Preoperative CHG Cloth on Healthy Subjects
Surgery
Primary: Percent Responder Rates of Bacterial Reduction on the Abdomen and Groin Sites — 80; 75; 86; 65 % of Treated Sites
Phase 4 N=112 Evaluation of Two Hand Hygiene Products in ICUs
Hand Hygiene Effectiveness
Primary: Bacterial Colony Forming Units Present on Hand Prints After Time Spent in Common Areas — 2.17; 1.81 log(10) transformed CFU
Phase 2 N=3,317 Study of the Efficacy of Plain Soap and Water Versus Alcohol-based Rubs for Surgical Hand Preparation
Postoperative Wound Infection
Primary: Surgical Site Infection — 128; 127 Participants — p=<0.05
Phase 3 N=22 Efficacy of Salivary Bacteria and Post Brushing
Salivary Bacteria Levels
Primary: CFU (Colony Forming Units) — 7.18; 6.94 number of colony forming units — p=0.05
Phase 1 N=5 Validation of the Short-term Antimicrobial Action of Transplanted Bacteria
Atopic Dermatitis
Primary: Relative Staphylococcus Aureus Abundance — 0.13; 12.2 ratio to baseline S. aureus abundance
N/A N=109 Bacterial Contamination of Healthcare Worker Uniforms
Bacterial Contamination of Healthcare Worker Uniforms
Primary: Total Bacterial Contamination of Healthcare Worker Uniform With Antimicrobial Properties Compared to Standard Healthcare Worker Uniform After an 8-hour Workday. — 41…
Phase 2 N=555 Effectiveness of an Antimicrobial Agent for Preoperative Skin Preparation
Preoperative Skin Preparation
Primary: Antimicrobial Activity of the Investigational Products Compared to Control. — 3.85; 3.91; 3.87; 3.84 log10 CFU/cm^2
Phase 4 N=33 A Two-week Crossover Evaluation of Two Hand Antiseptic Products on Skin Condition in Healthy Human Subjects
Healthy
Primary: Change From Baseline in Skin Health, Visual Skin Score (VSS) at 14 Days — 0.1; 0.4 units on a scale
Phase 4 N=46 Touch and Feel Evaluation of Two Foam Hand Sanitizers
Hand Hygiene
Primary: Primary Objective Foam Sanitizer User Touch and Feel Experience — 53.21; 39.62; 61.21; 49.73 score on a scale
Phase 3 N=329 Preoperative Skin Preparation Study to Evaluate the Antimicrobial Capabilities of Four Test Substances
Surgical Site Infection
Primary: Change in Bacterial Microflora in the Inguinal Area — -3.86; -4.34; -3.65; -3.80 log10 CFU
Phase 3 N=554 Preoperative Chlorhexidine Gluconate (CHG) Cloth on Healthy Subjects
Surgery
Primary: Percent Responder Rates (%) of Bacterial Reduction on the Abdomen and Groin — 93; 86; 50; 25 Percent of Sites
Phase 3 N=152 Pilot Evaluation of Two Test Materials With a Positive Control When Used as a Patient Preoperative Skin Preparation
Bacteria Microflora Reduction
Primary: Change in Bacterial Microflora on the Inguinal Area — -3.7; -3.1; -3.5 log10 CFU
Phase 3 N=24 Investigate Oral Bacteria in Adult Population
Oral Bacteria
Primary: Antimicrobial Species in Plaque(Actinomyces) — 0.023; 0.3881; 0.0538 log CFU (Colony forming units) — p=0.05
Phase 2 N=28 In Vivo Preoperative Skin Preparation Efficacy Study Within a Defined Product Coverage Area
Surgical Skin Preparation · Surgical Procedure, Unspecified
Primary: Comparison of Log Change of Skin Flora Relative to Pre-treatment (Baseline) in Each of 3 Sampling Sites at a Defined Post-treatment Sampling Time. — -2.19; -1.85; -2.42…
Phase 4 N=46 Wet Time for a Foam Hand Sanitizer
Hand Hygiene Effectiveness
Primary: Foam Sanitizer Wet Time Duration — 35.41 time in seconds
N/A N=15 Effect of Two Toothpastes on Bacteria in Saliva
Oral Health
Primary: Change From Baseline in Area Under the Curve Between 0 and 2 Hours (AUC [0-2] Hours) for Total Viable Counts (TVCs) of Bacteria in Saliva Using Traditional Plating…
Phase 3 N=135 Residual Effect of Chlorhexidine-alcohol Compared to Triclosan-alcohol
Infectious Diseases
Primary: Evaluate the Residual Effect of Chlorhexidine 2% / Isopropyl Alcohol 70% Administered Topically — 24; 48; 24 (CFU/cm2) — p=<0.05
Phase 3 N=170 Comparative Study of Antimicrobial Effectiveness
Bacterial Microflora Reduction
Primary: Change in Bacterial Microflora on the Inguinal Area — -3.92; -3.69; -3.94 log10 CFU
Phase 2 N=276 In Vivo Preoperative Skin Preparation Persistence Evaluation
Bacterial Recovery of Skin Flora Post-product Application
Primary: Measurement of Skin Flora Recovery Post-prep Application — 1.39; 1.15; 1.97; 1.82 log10 CFU/cm^2 — p=0.13
Phase 3 N=621 Preoperative Chlorhexidine Gluconate (CHG) Cloth on Healthy Volunteers
Surgery
Primary: Responder Rates (%) of Sites Identified for Bacterial Reduction on the Abdomen and Groin — 78; 84; 54; 56 Percent of sites
Phase 3 N=48 Povidone-iodine Against Sodium Hypochlorite as Skin Antiseptics
Healthy Volunteers
Primary: Bacterial Count of Skin Cultures for the 10% Povidone-iodine Period — 231 Colony-forming units per cm squared — p=<0.05
N/A N=30 Effectiveness of Preoperative Surgical Scrubbing Using Clorhexidine Digluconate and Parachlorometaxylenol (ECP)
Skin Diseases · Surgical Site Infection
Primary: Change in the Release of Skin Flora From the Hands From Baseline to 5 Minutes After Disinfection by Surgical Scrubbing (Time Frame- "Baseline and 5 Minutes"). — 3.96…
Phase 4 N=50 Evaluation of a Staphylococcus Eradication Protocol for Patients Who Present to the ED With Cutaneous Abscess
Cutaneous Abscess
Primary: Recurrence of Cutaneous Abscess — 5; 7 Participants
Phase 2 N=96 In Vivo Patient Preoperative Skin Prep Persistence
Bacterial Recovery of Skin Flora Post-Product Application
Primary: Measurement of Skin Flora Recovery Post-prep Application Relative to Baseline — 0.91; 2.81; 0.59; 2.96 Log10 CFU/cm^2 — p=<0.0001
N/A N=240 The Antiseptic Outcome of Traditional Hand Scrubbing Versus Hand Rubbing in Surgical Room
Hand Disinfection
Primary: Microorganisms on Hands Before Scrubbing — 28.99; 38.64; 22.91 colony forming unit
N/A N=210 Effect of Bed Bathing Methods on VRE Colonization in ICU Patients
Vancomycin-Resistant Enterococcus
Primary: Vancomycin-Resistant Enterococcus (VRE) Colonization — 0; 0; 30; 33 participants with VRE colonization — p=0.671