N/A N=126 Comparative Clinical Evaluation of Daily Disposable Lenses in Symptomatic Lens Wearers
Myopia
Primary: Lens Awareness — 16; 12; 11; 9 Participants
Clinical Trial Search
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N/A N=63 Comparative Clinical Evaluation of Daily Disposable Lenses in Symptomatic Daily Disposable Lens Wearers
Myopia
Primary: Lens Awareness — 8; 9 Participants
N/A N=37 Two Daily Disposable Contact Lenses in Symptomatic Patients
Myopia
Primary: Monocular Corrected Distance Visual Acuity (VA) — -0.01; -0.02 logMAR
N/A N=49 Clinical Evaluation of a Multifocal Contact Lens on Symptomatic Patients
Presbyopia
Primary: Subject Reported Overall Vision Quality Using (CLUE)TM Questionnaire — 41.0; 39.0 units on a scale
N/A N=42 Investigation of Ocular Signs & Symptoms in Wearers Fitted With Contact Lenses Following Digital Device Use
Visual Performance
Primary: Subjective Overall Comfort — 65.0; 53.6; 61.9 units on a scale
N/A N=45 The Impact of Soft Contact Lens Attributes on Symptoms Associated With Digital Eye Strain in Symptomatic Soft Contact Lens Wearers
Asthenopia · Myopia
Primary: Subject Reported Eye Fatigue — 18; 21; 21; 17 units on a scale — p=0.18
N/A N=591 Alcon Multi-Purpose Disinfecting Solution Versus Renu Fresh Multi-Purpose Solution in Symptomatic Contact Lens Wearers
Symptomatic Contact Lens Wearers
Primary: Likert Statement: When I Use This Solution, I Can Comfortably Wear my Lenses. — 3.9; 3.8 Units on a scale
N/A N=81 Clinical Characterization of Symptomatic Populations
Ametropia
Primary: Meibomian Gland Imaging — 10; 4; 23; 66 eyes
N/A N=88 Clinical Evaluation of a Daily Disposable Contact Lens in Symptomatic Weekly/Monthly Lens Wearers
Dry Eye Syndrome · Myopia
Primary: Mean Change From Baseline in Contact Lens-Related Dryness Symptoms at Week 1 and Week 2 — -0.09; -0.29 Units on a scale
Phase 4 N=30 Lifitegrast 5% for the Treatment of Dry Eye In Habitual Soft Contact Lens Wearers
Dry Eye
Primary: Efficacy of Lifitegrast Ophthalmic Solution 5% in Treating the Symptoms of Dry Eye in Contact Lens Wearers as Measured by Change in Total CLDEQ-8 Score From Baseline to…
Phase 4 N=73 Direct Application of Systane Complete to Contact Lenses
Dry Eye · Contact Lens Complication
Primary: Difference in Ocular Surface Damage as Measured by the Brien Holden Vision Institute (BHVI Grading Scale) at Two Weeks — 0.44; 1.08; 0.83 Score on a Scale — p=0.30
N/A N=65 Ocular Characteristics in Contact Lens and Spectacle Wear
Visual Acuity
Primary: Non-Invasive Break Up Time (NIBUT) or Non-Invasive Keratograph Break Up Time (NIKBUT) — 8.28; 11.10 Seconds
N/A N=134 Effectiveness of a Marketed One-Step Peroxide Lens Care Solution in Symptomatic Contact Lens Wearers
Refractive Error
Primary: Mean Change From Baseline in Investigator Rated Lid Papillae Maximum Score at Day 90 — 2.3; 2.3; 2.2; 2.2 units on a scale
Phase 4 N=50 Corneal and Conjunctival Sensitivity and Staining Study
Myopia · Hyperopia
Primary: Corneal Sensitivity — 26.9; 25.5 percent CO2
N/A N=25 Contact Lens Adaptation in Neophytes
Contact Lens Comfort
Primary: Between-Group Difference in Eye Comfort as Measured by the Ocular Surface Disease Index (OSDI) — 10.8; 16.3 Units on a Scale — p=0.83
Phase 4 N=46 Evaluation of Systane Complete for the Treatment of Contact Lens Discomfort
Contact Lens Discomfort · Dry Eye
Primary: Contact Lens Symptoms — 20.41; 18.92; 12.86; 17.92 Score on a Scale
N/A N=84 Accommodative Relief for Uncomfortable Non-Presbyopes
Asthenopia
Primary: Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) Score — 14.3; 12.8; 19.0 scores on a scale — p=<0.001
Phase 4 N=42 The Effect of Xiidra on Comfort and Dryness in Symptomatic Contact Lens Wearers
Dry Eye
Primary: Difference in Contact Lens-related Discomfort at 12 Weeks Compared to Baseline — 71; 11 score on a scale — p=<0.01
N/A N=37 Refitting Daily Disposable Contact Lens Wearers With Dry Eye Disease With A Different Daily Disposable Lens Type
Dry Eye
Primary: Subjective Comfort at End of Day With Contact Lens Wear — 72.5 score on a scale
N/A N=86 Performance of Dailies Total1® Contact Lenses for Astigmatism in Symptomatic Habitual Reusable Toric Lens Wearers
Astigmatism
Primary: Contact Lens Dry Eye Questionnaire (CLDEQ-8) Score — 16.8; 12.4 score on a scale
N/A N=23 Connecting Contact Lenses and Digital Technology
Asthenopia · Contact Lenses · Ocular Accommodation
Primary: Subjective Symptom Improvement — 153.9; 100.7; 272.13 score on a scale — p=0.07
N/A N=22 Comparing Silicone Hydrogel Contact Lens Wearers to Hydrogel Contact Lens Wearers and Non-lens Wearers
Myopia
Primary: Limbal Redness - DDSH, DDH, Non-lens Groups — 0.41; 0.37; 0.44; 0.49 score on a scale
N/A N=60 Dailies Total 1 Sphere Contact Lenses
Dry Eye · Contact Lens Complication
Primary: Visual Analog Scale (VAS) Contact Lenses Comfort Scores — 44 Score on a scale — p=<0.001
N/A N=30 Neurolens and Contact Lens Discomfort
Contact Lens Discomfort
Primary: Change in Contact Lens Discomfort — -4.94; -8.67 Scores on a scale
N/A N=84 Clinical Trial to Evaluate the Symptoms in Symptomatic Contact Lens Wearers Following Application of Intranasal Tear Neurostimulator Versus Control
Dry Eye Syndromes
Primary: Contact Lens Dry Eye Questionnaire (CLDEQ-8) Score in the Study Eye — 15.3; 17.2 score on a scale — p=0.116
N/A N=184 Late Night Study 2: End-of-Day Assessment of Asymptomatic and Symptomatic Soft Lens Wearers
Visual Acuity
Primary: Lid Margin Staining (Part1: Dailies Aqua Comfort Plus) — 1.02; 1.25; 1.45; 1.78 Units on a Scale
N/A N=61 A Clinical Study of the Comfilcon A Asphere Soft Contact Lens in Users of Digital Devices
Ametropia
Primary: Symptom of Burning — 0.16; 0.21; 1.00; 1.00 units on a scale
N/A N=24 Open Eye Corneal Swelling With Daily Disposable Contact Lenses and no Lens Wear
Corneal Swelling
Primary: Percentage Change From Baseline of Corneal Swelling 8 Hours Post Fit — 0.07; -0.02; 0.14; -0.06 percentage of change from baseline
N/A N=121 CLEAR CARE® PLUS for Presbyopic Contact Lens Wearers
Presbyopia
Primary: Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) Score at Day 30 — 12.6; 14.8 units on a scale — p==0.0073
N/A N=48 Total30 Sphere Contact Lenses
Contact Lens Complication · Dry Eye
Primary: Visual Analog Scale (VAS) Ocular Comfort — 36.66; 38.06; 33.68; 39.36 units on a scale — p=0.07