N/A N=9 Treatment of Painful Digital Neuroma Using A Pedicled Nerve Flap
Painful Digital Neuroma
Primary: Static 2-point Discrimination Test — 7.3 mm
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=86 Study of AxoGuard® Nerve Cap and Neurectomy for Treatment of Symptomatic Neuroma & Prevention of Recurrent Neuroma Pain
Symptomatic Neuroma · Morton's Neuroma · Chronic Nerve Pain
Primary: Change in Visual Analog Scale (VAS) For Pain Score at 12 Post-operative Months in Comparative Phase Subjects — -86.62; -72.67 Millimeters (mm) — p=0.011
N/A N=8 C-RFA of Residual Limb Neuroma
Phantom Limb Pain · Neuroma Amputation
Primary: Numeric Rating Scale (NRS) for Pain at 6 Months — 4 Participants
N/A N=26 Surgical Treatment of Post-surgical Mastectomy Pain Utilizing the Regenerative Peripheral Nerve Interface
Post-Mastectomy Chronic Pain Syndrome
Primary: Change in Pain Level — 6.9; 0.6; 4.4; 2.5 score on a scale
Phase 3 N=140 Evaluation in the Treatment of Neuropathic Pain Post Breast Surgery
Breast Cancer Patient
Primary: Change in Neuropathic Pain Score at 2 Months (Numeric Rating Scale 0-10) — 4.1; 4.6 units on a scale
Phase 2 N=9 Medical Treatment of "High-Risk" Neurofibromas
Neurofibromatosis 1
Primary: Improvement of Symptoms and Pain — 9 Participants
N/A N=41 Neurogenic Inflammation in Diabetes
Diabetes Mellitus · Polyneuropathies · Arthropathy, Neurogenic
Primary: Induration Size as a Response to Intracutaneous Candida Albicans. — 4; 6; 5; 4 millimeters — p=0.84
N/A N=40 Venous Insufficiency and Neuromuscular Stimulation
Chronic Venous Disease · Venous Insufficiency · Deep Venous Obstruction
Primary: Percentage Change of Haemodynamic Flow — 34.8; 62.8; 9; 14.8 % change
Phase 2 N=27 Bevonescein to Highlight Nerves in Patients Undergoing Head & Neck Surgery
Parotid Neoplasm · Thyroid Neoplasms · Head and Neck Neoplasms
Primary: Safety - The Number of Patients With ALM-488 Related Adverse Events — 0; 0; 0; 0 Participants
N/A N=138 Treatment for Ulnar Neuropathy at the Elbow
Peripheral Nervous System Diseases · Nerve Compression Syndromes · Cubital Tunnel Syndrome
Primary: UNEQ Score — 2; 2; 1.9; 1.9 score on a scale
N/A N=19 MRI Diffusion Tensor Tractography to Monitor Peripheral Nerve Recovery After Severe Crush or Cut/Repair Nerve Injury
Nerve Injury
Primary: Michigan Hand Questionnaire (MHQ) in TPNI Subjects Post Surgery — 33; 83; 5; 75 score on a scale
Phase 2 N=14 Bevacizumab for Symptomatic Vestibular Schwannoma in Neurofibromatosis Type 2 (NF2)
Vestibular Schwannoma · Neurofibromatosis Type 2
Primary: Proportion of Patients With Hearing Response — 0.36; 0.50 Proportion with hearing response
N/A N=7 Percutaneous Peripheral Nerve Stimulation (Neuromodulation) for Postoperative Analgesia
Postoperative Pain
Primary: Change From Baseline of Surgical Site Pain Level (NRS) at Rest [Percentage of Baseline Pain] — 64; 100; 55; 69 percentage of baseline
Phase 4 N=52 Ultrasound Guided Distal Peripheral Nerve Blocks and Postoperative Pain.
Postoperative Pain
Primary: Proportion of Patients Who Experienced Moderate to Severe Pain During First and Second Postoperative Day — 8.3; 80.8; 4.2; 42.3 percentage of patients
N/A N=423 Neuropathic Pain After Orchidectomy and Sex Reassignment Surgery
Neuropathic Pain · Phantom Pain · Sex Reassignment Surgery
Primary: Incidence of Phantom Pain — 6; 0 Participants — p=0.013
N/A N=9 Repair of Infective Wound Associated With Nerve Defect in the Finger Using A Bipedicled Nerve Flap
Infection Wound · Disruption of Nerve Repair
Primary: 2-point Discrimination Test — 7.5 mm
N/A N=15 Neo-nervegenesis in Inguinal Hernia Implant ProFlor
Inguinal Hernia
Primary: Ingrowth of Newly Formed Nervous Elements Within Hernia Implant ProFlor — 999.75; 1044; 2094 μm^2 — p=0.028
N/A N=16 Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain
Phantom Limb Pain · Postoperative Pain · Neuroma
Primary: Average Phantom Limb Pain (PLP) Score — 4.1; 3.1; 2.2; 3.0 score on a scale
N/A N=63 Chronic Neuropathy Following Chemotherapy
Peripheral Nervous System Diseases · Chronic Pain
Primary: Chemotherapy-induced Peripheral Neuropathy — 21 participants
N/A N=20 HIFU Treatment of Cutaneous Neurofibromas in Neurofibromatosis Type 1: Safety and Efficacy
Cutaneous Neurofibroma
Primary: Short Term Safety Profile - Adverse Events — 0; 20 Participants
N/A N=22 Nociceptive Pain Fiber Response
Painful Peripheral Diabetic Neuropathy
Primary: Changes in Small Nerve Fiber Density by Assessment of a Skin Biopsy Comparing Baseline to Day 60 — .1; .1 nerve fibers / mm squared
N/A N=40 Neuromonitoring During the Latarjet Procedure
Shoulder Instability · Iatrogenic Nerve Injury
Primary: Neurologic Complication Rate After Latarjet Procedure — 7 participants
N/A N=116 Peripheral Nerve Stimulation(PNS) for Subacromial Impingement Syndrome(SIS)
Shoulder Pain · Shoulder Impingement Syndrome · Shoulder Tendinitis
Primary: Change in - Short Form (SF) Question 3 (BPI-SF3) — 6.90; 7.05; 3.58; 3.96 units on a scale
N/A N=60 Local Effects of Acupuncture and Nerve Conduction Studies
Carpal Tunnel Syndrome
Primary: Change in Median Cold Detection Threshold (CDT) Post-acupuncture Compared to Pre-acupuncture When the Median Nerve is Treated — 0.73; -0.195; 0.865 JND (just noticeable…
Phase 4 N=21 Symptom Management After Breast Cancer Surgery
Neuropathic Pain · Postmastectomy Pain
Primary: Change in Pain Intensity on an 11-point Scale From Baseline to 12 Weeks — 4.0 units on a scale
Phase 4 N=60 Ultrasound Guided Trigeminal Nerve Block for Typical or Atypical Facial Pain
Typical Facial Pain · Atypical Facial Pain
Primary: The Proportion of Subjects Reporting at Least 50% Overall Pain Relief — 19; 14; 10; 16 Participants — p=.196
Phase 2 N=18 AZD2014 In NF2 Patients With Progressive or Symptomatic Meningiomas
Neurofibromatosis 2 · Meningioma
Primary: Radiographic Response Rate for Target Meningioma — 1 target meningiomas
N/A N=4 Epidural Spinal Cord Stimulation for Sensory Restoration and Phantom Limb Pain in Upper-Limb Amputees
Phantom Limb
Primary: Stimulation Thresholds to a Variety of Stimulus Parameters — 2.13 milliamps
N/A N=36 The Effect of Additional Neurodynamic Intervention in Patients With Chronic Ankle Instability
Ankle Sprains
Primary: Pressure Pain Threshold- Anterior Talofibular Ligament — 4.19; 3.98 kg/ cm²
N/A N=8 Technical Efficacy of a Direction Specific Radiofrequency Device in the Performance of Lumbar Medial Branch Neurotomies
Low Back Pain
Primary: Percentage of Patients With Magnetic Resonance Imaging (MRI) Evidence of Tissue Ablation/Edema at Targeted Lumbar Medial Branches — 100 percentage of participants