N/A N=90 Donor After Circulatory Death Heart CAP Trial
Heart Transplant
Primary: Patient Survival — 75 Participants
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Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=180 Donors After Circulatory Death Heart Trial
Heart Transplant
Primary: Survival — 76; 75 Participants — p=<0.0001
N/A N=320 International Randomized Study of the TransMedics Organ Care System (OCS Lung) for Lung Preservation and Transplantation
Lung Preservation
Primary: A Composite of Patient Survival at Day 30 Post Transplantation, and Absence of International Society for Heart & Lung Transplantation (ISHLT) Primary Graft Dysfunction…
N/A N=321 Remote Ischemic Preconditioning in Neurological Death Organ Donors
Organ Transplantation
Primary: Number of Organs Recovered Per Donor — 3.79; 3.60 organs recovered per donor — p=0.38
N/A N=300 OCS Liver PROTECT Trial: Preserving and Assessing Donor Livers for Transplantation
Liver Transplantation · Liver Preservation for Transplant
Primary: Participants With Early Liver Allograft Dysfunction (EAD) — 27; 44; 27; 47 Participants — p=<0.0001
N/A N=273 A Randomized Trial of the Early Referral and Request Approach (ERRA) Intervention to Increase Consent to Organ Donation
Organ Donation
Primary: Change in Authorization Rates for Solid Organ Donation From Families of Donor-eligible Patients — 78; 80; 89; 81 Percentage of successful requests
N/A N=103 Enhancing Donated After Cardiac Death (DCD) Utilization With Thrombolytic Therapy
Liver Transplantation · Kidney Transplantation
Primary: Delayed Kidney Graft Function — 5; 7 Participants
N/A N=75 International EXPAND Heart Pivotal Trial
Heart Transplant
Primary: Patient Survival at Day-30 Post Transplant and Absence of Severe Primary Heart Graft Dysfunction in the First 24 Hours Post-transplantation — 66 Participants — p=<0.0001
N/A N=72 Don't Throw Your Heart Away: Clinician Study 3
Cardiac Transplant Disorder
Primary: Hospital Choice — 4; 21; 34; 13 Participants
N/A N=1,019 Don't Throw Your Heart Away: Layperson Study 1
Cardiac Transplant Disorder
Primary: Hospital Choice — 64; 125; 163; 192 Participants
N/A N=105 Don't Throw Your Heart Away: Medical Student Study 2
Cardiac Transplant Disorder
Primary: Hospital Choice — 33; 47; 23; 2 Participants
Phase 3 N=838 Intravenous Thyroxine for Heart-Eligible Organ Donors
Brain Death · Heart Failure
Primary: Heart Transplanted — 230; 223 Participants — p=0.57
N/A N=75 Heart EXPAND Continued Access Protocol
Heart Transplant
Primary: Patient Survival at Day 30 Post-transplantation and Absence of Severe PGD (Left or Right Ventricle) in the First 24 Hours Post-transplantation — 72 Participants
Phase 4 N=64 Tissue Glue (Cyanoacrylate) Versus Conventional Suture in Kidney Donors
Skin Closure of Surgical Incisions by Tissue Glue vs Suture
Primary: Wound Healing by Numerical Scales for Rubor Postoperative Day 2. — 0.516; 0.984 units on a scale
N/A N=20 Trial to Compare the SherpaPak™ Device vs Cold Storage
Organ Transplant
Primary: Absence of Moderate to Severe Primary Graft Dysfunction (Left or Right Ventricle) — 10; 10 Participants
N/A N=24 Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability
Emphysema · Chronic Obstructive Pulmonary Disease (COPD) · Cystic Fibrosis
Primary: 30 Day Mortality and Graft Survival — 0; 22; 0; 2 Participants
Phase 4 N=11 Expanded Access Protocol Thymus Transplantation
Poor Thymic Function · Immunodeficiency · Athymia
Primary: Survival Rate at End of 1 Year — 90.9 percentage of participants
N/A N=300 Transplant Social Worker Support for Live Kidney Donation in African Americans
Kidney Disease
Primary: Number of Participants With Live Kidney Donor Activation Events — 87; 86; 88; 5 Participants
N/A N=49 Hypothermic Machine Preservation-Phase 2
Liver Damage
Primary: Patient Survival at One Year Post-Transplantation — 19; 19 participants
Phase 4 N=26 Panel Reactive Antibody (PRA) Reduction in Sensitized Patients Awaiting Renal Transplantation
End Stage Renal Disease
Primary: The Percent of Sensitized Patients Treated With PRA Reduction Pharmacological Therapy, Including Cytogam, Who Become Cross-match Compatible With Potential Living Donor…
N/A N=74 OCS Liver PROTECT Continued Access Protocol
Liver Transplant
Primary: Participants With Early Liver Allograft Dysfunction (EAD) — 19 Participants
N/A N=56,332 Disparities in National Kidney Allocation Policy
Kidney Disorders
Primary: Proportion of Incident Patients Waitlisted — 1.39; 1.33; 1.25; 1.30 adjusted mean proportion of patients
N/A N=267 WP01 - Normothermic Liver Preservation
Liver Transplantation
Primary: Percentage of Participants With Early Allograft Dysfunction (EAD) — 20.6; 23.7 percentage of participants
Phase 3 N=199 Naloxone for Optimizing Hypoxemia Of Lung Donors
Brain Death · Organ Donors · Lung Transplantation
Primary: Change in Oxygenation (P/F Ratio) From Baseline to Final Pre-recovery Arterial Blood Gas (ABG) — 81; 80 mm Hg
N/A N=79 International EXPAND Lung Pivotal Trial
Lung Transplant
Primary: Number of Participants With Composite Endpoint of Patient Survival at Day-30 Post Transplant and Absence of Primary Graft Dysfunction (PGD) Grade 3 During the First 72…
Phase 2 N=15 StrataGraft™ Skin Tissue (Human Donor Skin) In The Surgical Management Of Complex Skin Defects
Third Degree Burn · Burns · Wound Infection
Primary: Percent Autograft Take on Wounds Prepared by StrataGraft™ Skin Tissue. — 97.7; 96.7 Percent Area of Autograft Take (%)
N/A N=784 Healthcare Utilization in Obese Caregiver Living Donors
Utilization, Health Care · Obesity
Primary: Emergency Department Utilization — 77; 305 Participants
N/A N=22 Autologous Regeneration of Tissue (ART) for Wound Healing
Wound of Skin
Primary: Change of Pain on Harvesting of Skin at Donor Site. — 2.6 millimeters
N/A N=118 Extending Preservation and Assessment Time of Donor Lungs Using the Toronto EVLP System™ at a Dedicated EVLP Facility
Lung Disease
Primary: Count of Participants With Primary Graft Dysfunction (PGD), Grade 3 — 8; 8; 2 Participants
N/A N=416 Reducing Disparities in Living Donor Transplant Among African Americans
Kidney Transplant
Primary: Percent of Patients With at Least One Inquiry From a Potential Living Donor — 15.63; 15.63; 15.77; 15.87 percentage of participants