Phase 3 N=626 The Efficacy of a Toothpaste to Reduce Sensitivity
Dentin Hypersensitivity
Primary: Hypersensitivity Tactile(Yeaple Probe) — 19.81; 13.94 units on a scale — p=0.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=79 Clinical Efficacy of a Toothpaste on Hypersensitivity Reduction
Hypersensitivity
Primary: Tooth Hypersensitity to Touch Stimuli (Tactile) — 10.83; 10.63 Units on a scale — p=0.05
N/A N=192 Trial of Nano-hydroxyapatite-Containing Toothpastes for Relief of Dentin Hypersensitivity
Dentin Sensitivity
Primary: Measurement of Cold Air Stimulus — 71.4; 72.2; 71.9; 51.1 units on a scale
N/A N=263 A Study to Measure the Efficacy of a Toothpaste on Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Thermo-evaporative (Schiff Air Blast) Stimuli — 2.188; 2.246; 1.268; 1.811 score on a scale — p=<0.001
Phase 3 N=113 Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Day 14 — -1.20; -0.37 Score on a scale — p=<0.0001
N/A N=22 A Clinical Study to Compare Professional Treatments for Dentinal Hypersensitivity
Dentinal Hypersensitivity
Primary: Change From Baseline Air Challenge — -0.55; -0.95 Units on a scale
N/A N=120 A Clinical Study to Assess the Effects of Various Dentifrice Technologies on Dentinal Hypersensitivity
Dentin Hypersensitivity
Primary: Air Challenge — 1.17; 1.48; 2.26; 1.39 score on a scale
Phase 3 N=118 The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Mean Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Week 8 — -0.9; -0.5 Score on a scale — p=<0.0001
N/A N=215 A Clinical Study to Evaluate the Anti-Sensitivity Effect of a Calcium Sodium Phosphosilicate Toothpaste in a Population of Dentin Hypersensitivity Sufferers
Dentin Sensitivity
Primary: Adjusted Mean Change From Baseline in Schiff Sensitivity Score at Day 56 — -2.00; -0.20 score on a scale — p=<0.0001
N/A N=30 A Clinical Study of Two Dentinal Hypersensitivity Treatments Used With Normal Oral Hygiene
Dentin Sensitivity
Primary: Change From Baseline Air Challenge — -1.643; -1.500 Units on a scale
N/A N=120 Study to Evaluate the Effectiveness of Test Dentifrice in the Relief of Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Adjusted Mean Change From Baseline in Schiff Sensitivity Score at Week 12 (Test Dentifrice Versus [vs] Negative Control Dentifrice) — -1.19; -0.44 score on a scale…
Phase 3 N=120 The Efficacy of a Dentifrice in Providing Relief From Immediate and Short Term Relief From Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Change From Baseline in Schiff Sensitivity Score on Day 14 — 2.51; 2.51; 1.16; 1.35 score on a scale — p=0.1774
N/A N=375 Test on a New Experimental Mouth Rinse for Relieving Tooth Sensitivity
Dentin Sensitivity
Primary: Percentage of Subjects With Reduction From Baseline by at Least 30% in Mean Cold Air VAS Stimulus Score at Week 4 — 44.6; 69.3 percentage of participants — p=<0.001
N/A N=174 Tooth Sensitivity Relief by Two Mouthrinses
Dentin Sensitivity
Primary: Mean Tactile Sensitivity Score at Week 6 — 37.91; 36.77; 30.16 grams — p=0.811
N/A N=153 A Test on a New Experimental Mouth Rinse for Relieving Tooth Sensitivity
Dentin Sensitivity
Primary: Mean Tactile Sensitivity Score at Week 4 — 11.21; 23.81; 22.07 grams of force — p=<0.001
N/A N=36 Effects of an Oxalate Containing Product on Dentinal Hypersensitivity With Dental Prophylaxis
Dentin Sensitivity
Primary: Change From Baseline Air Challenge — -0.412; -0.132 Units on a scale
N/A N=304 Clinical Study to Evaluate the Efficacy of Two Dentifrices for Dentine Hypersensitivity
Dentine Sensitivity
Primary: Mean Change From Baseline in Evaporative Air Sensitivity as Measured by Visual Analogue Score (VAS) at Week 8 — 53.05; 55.89; 31.62; 30.51 score on a scale — p=0.2678
N/A N=230 The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score on Day 3 — -0.96; -0.77 Score on a scale — p=0.1575
Phase 4 N=141 Study to Investigate the Efficacy of an Occluding Dentifrice in Providing Relief From Dentine Hypersensitivity
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score at Day 14 — 2.70; 2.74; -1.38; -0.10 score on a scale — p=<0.0001
N/A N=135 Assessment of the Efficacy of an Experimental Occlusion Technology Dentifrice in Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score at Week 8 — -0.94; -0.33 score on a scale — p=<.0001
Phase 3 N=140 Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH
Dentin Hypersensitivity
Primary: Percent Change in Mean Score of Pain Response From Baseline on Schiff Cold Air Sensitivity Scale Using Air Blast Stimulus — 18; 45; 37; 15 percentage of change in mean…
N/A N=185 A Clinical Study to Evaluate a Stannous Fluoride Toothpaste for the Relief of Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score After 8 Weeks of Treatment — 2.22; 2.23; 2.18; 1.69 Score on Scale — p=0.0476
N/A N=204 The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity (DH)
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score on Day 3 — -1.37; -0.45 score on a scale — p=<.0001
N/A N=118 Pilot Study to Investigate the Efficacy of a Toothpaste in Providing Relief From Dentinal Hypersensitivity
Dentinal Sensitivity · Hypersensitivity
Primary: Adjusted Mean Change From Baseline in Tooth Hypersensivity to Air Stimuli Immediately Following Treatment — -0.42; -0.32 units on a scale — p=0.2294
Phase 4 N=192 To Investigate the Efficacy of an Occluding Dentifrice in Dentinal Hypersensitivity (DH)
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score on Day 3 — 2.44; 2.49; 1.01; 2.37 Score on a scale — p=<.0001
N/A N=655 A Real-World Evidence Study to Evaluate Oral Health Related Quality of Life Using an Anti-Sensitivity Toothpaste
Dentin Sensitivity
Primary: Mean Score of DHEQ Section 1 - Impact on Everyday Life (Question [Q]1-3) at Baseline (Day 0) — 5.90; 6.17; 5.20 score on a scale
Phase 2 N=203 Clinical Efficacy in Relieving Dentin Hypersensitivity of Nanohydroxyapatite-Containing Toothpastes and Cream
Dentin Sensitivity
Primary: Percentage Change From Baseline in VAS (Visual Analog Scale) With Air Stimulation — -51.44; -51.59; -41.59; -38.64 percentage change from baseline
Phase 1 N=12 The Effects of Potassium Nitrate in Reducing Dentinal Hypersensitivity
Dentinal Hypersensitivity · Dental Pain
Primary: Adjusted Mean Change From Baseline in Evaporative Sensitivity Pain Response of Hypersensitive Tooth on a Visual Analogue Scale (VAS) Immediately Post Application of 5%…
N/A N=101 A Comparison Study of Hypersensitivity Treatment
Dentin Hypersensitivity
Primary: Change in Pain From Baseline Immediately After Application of Test Product. — 8.9; 8.6 units on a scale
Phase 4 N=222 Short Term Clinical Study Investigating the Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score on Day 3 — -0.40; 0.00 Score on a scale — p=<0.0001