Phase 3 N=187 MOM Program 8-Year Follow-up
Child Development
Primary: Woodcock-Johnson Cognitive Ability Test, 3rd Edition (WJR-III, Cog) — 89.32; 87.62 units on a scale — p=0.39
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=156 Comparison of Telemedicine to Usual Care for HCV Management for Methadone-maintained Individuals
Hepatitis C
Primary: Observed Percentage of Patients in Both Arms Who Achieve Viral Eradication — 106; 246 Participants
N/A N=667 LINK: Aftercare Monitoring Project
Alcohol Dependence · Drug Dependence
Primary: Rates of Substance Use — 91.1; 88.0 percentage of days
N/A N=78 Completion of OST - a Prospective Study
Opioid Dependence
Primary: Completion of OST — 9 participants
N/A N=124 Adolescents' Well-being in Community-based Treatment Versus Residential Treatment
Adolescent Well-Being · Mental Disorders, Severe
Primary: Average Z-score From Participant Self Report on Domains in the Clinical Scale of the Treatment Outcome Package (TOP-CS) at Study Intervention Endpoint — 0.42; 0.63 Z-score
N/A N=10 Development of a Community-based HCV Treatment Completion Intervention Among HCV Positive Homeless Adults
Hepatitis C Virus (HCV) Infection
Primary: Number of Participants Completing HCV Treatment — 3; 6 Participants
N/A N=3,000 Supporting Treatment Outcomes Among PWID
Hepatitis C · HIV Coinfection
Primary: Sustained Virologic Response (SVR) by Intervention Group Stratified by Defined Risk for Treatment Failure (Minimal vs Elevated) — 638; 416; 233; 76 Participants
Phase 3 N=500 Adaptive Treatment for Alcohol and Cocaine Dependence
Substance Use Disorders
Primary: Treatment Engagement — 3.92; 3.50 treatment days — p=0.11
Phase 2 N=183 Reinforcement of Abstinence and Continuing Care in Substance Abuse Treatment
Substance Use Disorders · Alcohol Abuse · Alcoholism
Primary: Abstinence Rate (During the Preceding 90 Days) at 12 Months Follow-up Point as Assessed by the Form-90 — 40; 38; 47; 51 participants
Phase 4 N=700 Sequenced Treatment Effectiveness for Posttraumatic Stress
PTSD
Primary: PTSD Symptoms — 39.3; 38.6; 40.5 units on a scale
N/A N=249 Observational Study to Compare Outcomes of Different Psychiatric Treatment of Suicidal Adolescents
Suicidal Ideation
Primary: Number of Recurrent Suicidal Events Measured by Treatment Arm — 0.66; 0.45; 0.20; 0.60 hospitalizations
N/A N=240 The Effectiveness of a Decision-Support Tool for Adult Consumers With Mental Health Needs and Their Care Managers
Mental Disorders
Primary: Short Form Health Survey-12 (SF-12), Physical Symptoms Subscale — 38.167; 38.601; 37.187; 37.108 units on a scale — p=.0679
N/A N=48 SMART Effectiveness Trial
Opioid-use Disorder · Opioid Dependence · Treatment Adherence
Primary: Treatment Adherence — 16; 13 Participants
N/A N=4 A Novel Treatment for Aphasia and Apraxia of Speech : Measurement of Outcomes
Apraxia of Speech · Aphasia
Primary: Change in Language Content Production for Treated Stimuli: Effect Sizes (Magnitude of Change From Baseline to Follow-up) — 13.38 units on a scale
N/A N=298 Mechanisms of Action and Outcome
Mental Disorders
Primary: Patient Activation — 29.12; 28.82; 29.21 units on a scale
N/A N=12 A Self-Management Program for Completers of Trauma-Focused Therapy for PTSD
Posttraumatic Stress Disorder
Primary: Credibility-Expectancy Scale (Credibility Subscale) — 6.39 score on a scale
N/A N=79 Integrated Care for Patients With High Risk Substance Use and Psychiatric Disorder With Chronic Direct Acting Antiviral Treatment
Hepatitis C · Depression · PTSD
Primary: Sustained Viral Response (SVR) — 30; 12.8 percentage of Participants — p=0.07
N/A N=45 Positive Processes and Transition to Health
Major Depressive Disorder · Post Traumatic Stress Disorder
Primary: Affective Updating Task (Pe et al., 2013; Pe, Raes, et al., 2013) — 0.54 units on a scale
N/A N=544 TOP Implementation Project
Posttraumatic Stress Disorder
Primary: Reach: the Proportion of Sampled Patients Who Received the Core Element of the TOP Intervention — 172; 43; 41; 13 Participants
N/A N=364 An Integrated Care Model for Improving Hepatitis C Virus Patient Outcomes
Hepatitis C
Primary: Sustained Virologic Response Rates — 29; 14 participants
N/A N=72 Metacognitive-Strategy Training in Sub-Acute Stroke
Stroke
Primary: Canadian Occupational Performance Measure (COPM) — 3.77; 3.87 score on a scale — p=.693
N/A N=832 Testing an Organizational Change Model to Address Smoking in Mental Healthcare
Nicotine Dependence
Primary: Client Reported Tobacco Medications — 48; 28; 62; 24 Participants
N/A N=142 PracticeGround: Transforming Training and Delivery of Mental Health EBPs
Depression · Insomnia · Suicide
Primary: Depression, Anxiety, and Stress Scale (DASS) — 1.55; 1.68; 1.32; 1.4 score on a scale — p=.734
N/A N=33 Efficacy of the Recovery Workbook as a Psychoeducational Tool for Facilitating Recovery
Mental Disorders
Primary: Hope Herth Index — 38.93; 35.06 units on a scale
N/A N=7,526 An Evaluation of Virtual Psychiatric Transition of Care Offered in Behavioral Health
Mental Health Issue
Primary: Number of Participants With All Cause Non-elective Acute Care Post Discharge Utilization Within 30 Days — 941; 973 Participants — p=<0.001
N/A N=211 TAU Opioid Use Outcomes Following Discharge From Detoxification and Short Term Residential Programs Affiliated With CTN-0051
Opioid Use Disorder
Primary: Days of Opioid Use — 6.8 days
N/A N=350 Evaluation of Outcomes for Quality of Life and Activities of Daily Living for BKP in the Treatment of VCFs
Compression Fracture of Vertebral Body · Osteoporosis · Cancer
Primary: Back Pain Change From Baseline at 3 Months — 8.7; 2.7; -6.0 units on a scale
N/A N=146 Telephone Disease Management At-Risk Drinking (TDM II)
Alcohol Abuse
Primary: Reduced Alcohol Use — 14.96; 15.52 Days drinking
N/A N=415 Pilot Randomized Controlled Trial (RCT): Remote SBIRT Vs. In-Person SBIRT
Pregnancy · Substance Use · Depression
Primary: Completion of SBIRT (Specific Aim 1) — 221; 63 Participants
N/A N=321 Effectiveness of Extended Treatments for Drug Dependence
Cocaine Dependence
Primary: Abstinence — 45; 57; 45 participants