N/A N=132 Impact of Vitamin B12 Replacement on Epogen Dosing and Improvement of Quality of Life in Hemodialysis Patients
Vitamin B12 Deficiency
Primary: Change in Amount of Epogen Required — -16,572 unit/ml
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=21 Evaluation of Holotranscobalamin as an Indicator of Vitamin B12 Absorption
Disorder of Vitamin B12
Primary: Change in Holo-transcobalamin — 124 pmol/L
N/A N=41 Vitamin B12 for Aromatase Inhibitors Musculoskeletal Symptoms
Relief of Joint Pain
Primary: Percentage Change in Average Joint Pain in Women With Aromatase Inhibitor-associated Musculoskeletal Symptoms (AIMSS) Compared to Baseline as Measured by the Brief Pain…
N/A N=366 Randomized Trial of Vitamin B12 in Pregnant Indian Women
Pregnancy
Primary: Changes in Maternal Serum B12 Concentration From 1st to 3rd Trimester — 3.0; -37.6 pmol/L
N/A N=125 Autoantibodies to Gastric Parietal Cells in Rheumatoid Arthritis Patients
Vitamin B12 Deficiency
Primary: Prevalence of Vitamin B12 Deficiency — 3; 6; 4 participants
Phase 2 N=20 A Trial of Vitamin B12 in Septic Shock
Septic Shock
Primary: Feasibility of Clinical and Protocol Completion — 10; 10 Participants
N/A N=30 Natural Versus Synthetic Vitamin B Complexes in Human
Healthy · Thiamine and Niacin Deficiency States · Pyridoxine Deficiency
Primary: Serum Thiamine — 50.21; 48.33; 51.21; 50.60 "µg/L"
Phase 3 N=319 A Randomized Phase III Study of Vitamins B6 and B12 to Prevent Chemotherapy-Induced Neuropathy in Cancer Patients
Cancer
Primary: Neurotoxicity Assessment at Baseline — 8.5; 7.3; 5.23; 4.58 units on a scale
N/A N=206 Prevalence of Thiamine Deficiency in Hospitalized Non-Alcoholic Veterans
Thiamine Deficiency · Thiamine Deficiency; Sequelae
Primary: Percentage of Participants With Thiamine Deficiency (Low Plasma Thiamine) Out of Total Number of Enrolled Veterans With Plasma Thiamine Results — 49 Participants
Phase 4 N=140 Effectiveness of Vitamin Supplementation in Treating People With Residual Symptoms of Schizophrenia
Schizophrenia
Primary: Positive and Negative Syndrome Scale (PANSS) — -.21; -.22 units on a scale
N/A N=90 Vitamin D Replacement After Kidney Transplant
Kidney Transplantation · Vitamin D Deficiency
Primary: Compare Efficacy and Safety of Two Vitamin D Supplements of These Doses in Normalizing Vitamin D Concentrations. — 8; 29 ng/ml
N/A N=63 Vitamin B12 and Folate Administration on Homocysteine Concentrations After Nitrous Oxide Anesthesia
Cardiovascular Abnormalities
Primary: Change in Plasma Total Homocysteine Concentration (tHcy) — 1.9; 2.7; 0.5 mcmol/L — p=<0.05
Phase 4 N=160 Vitamin Deficiency in Immigrants, a Treatment Study
Vitamin D Deficiency
Primary: Serum-vitamin D — 19.7; 34.4; 38.7; 58.7 25(OH)D, nmol/L — p=0.001
N/A N=37 Efficacy of Vitamin D Supplementation in Bariatric Surgery Patients
Obesity · Vitamin D Deficiency
Primary: Vitamin D Concentrations, Pre Operative and Post Bariatric Surgery Following 12 Weeks of Vitamin D Supplementation — 19.1; 27.2 ng/mL — p=< 0.001
N/A N=81 Optimizing Vitamin D in the Elderly
Deficiency of Vitamin D3
Primary: Total 25-OH Vitamin D3 Level — 33; 34; 43; 61 ng/mL — p=<.0001
N/A N=19 Ultraviolet Light And Vitamin D In Subjects With Fat Malabsorption Or After Gastric Bypass Surgery
Vitamin D Deficiency · Gastrointestinal Diseases
Primary: # of Pts w/ Enhanced Vitamin D Status — 3; 3 Participants
Phase 3 N=57 Trial of Methyl B12 on Behavioral and Metabolic Measures in Children With Autism
Autistic Disorder
Primary: Clinical Global Impression-Improvement (CGI-I) — 3.1; 2.4 CGI- Improvement
N/A N=28 Famine From Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes
Diabetes Type 2
Primary: Diff AUC SS0.5 Hyperglycemic — 0.74; 0.96 Pa*hr
N/A N=20 Vitamin D Supplementation in Kidney Disease
Renal Dialysis · Vitamin D Deficiency
Primary: Change in Hip Flexor Strength — 20.34; 6.83 percent change
N/A N=68 Improving Vitamin D Status in Home-bound Elders
Vitamin D Deficiency · Accidental Falls
Primary: Change in 25-hydroxyvitamin D Levels Over 5 Months — 21.7; 0 ng/mL
Phase 3 N=13 Vitamin B6 Effects for Women Taking Birth Control Pills
Vitamin B6 Deficiency
Primary: Total Remethylation of Homocysteine — 6.07; 5.63 micromol/(kg x hr) — p=0.20
N/A N=179 Cholecalciferol in Newly Diagnosed Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukemia With Vitamin D Deficiency
Chronic Lymphocytic Leukemia · Non-Hodgkin Lymphoma · Untreated Chronic Lymphocytic Leukemia
Primary: Progression-free Survival — 0.839; 0.893; 0.827 Proportion of participants
Phase 3 N=265 Vitamin D Status of Pregnant Women and Their Children in Eau Claire, South Carolina
Vitamin D Deficiency · Pregnancy
Primary: 25-hydroxyvitamin D at Visit 7 — 36.7; 39.8 ng/mL
N/A N=95 Vitamin D to Improve Outcomes by Leveraging Early Treatment: Long-term Brain Outcomes in Vitamin D Deficient Patients
Cognitive Decline
Primary: 12-month Cognition as Measured by the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) — 79.6; 82.1 units on a scale
N/A N=96 Vitamin D Repletion in Coronary Artery Disease
Vitamin D Deficiency · Coronary Artery Disease · Endothelial Dysfunction
Primary: Endothelial Function — 0.13; -0.04 reactive hypermia index
N/A N=96 Impact of Vitamin D Repletion in Hemodialysis Patients
Vitamin D Deficiency · End-stage Renal Disease
Primary: Change in 25OH-Vitamin D Level — 15.8; 40.9 ng/dL
Phase 3 N=130 Vitamin D in Vulnerable Adults (VIVA-VA)
Frail Elderly · Vitamin d Deficiency
Primary: Change in Short Physical Performance Battery Test Score — 7.3; 7.0 units on a scale
Phase 4 N=11 Is Treatment of Vitamin D Deficiency Associated With Resolution of Statin-Induced Muscular Symptoms
Myopathic Symptoms
Primary: Number of Participants With Reduction in Myopathic Pain — 4; 4 Participants
Phase 3 N=402 Sub-clinical Inflammation and Iron Supplementation
Anemia
Primary: Haemoglobin Level — 88.3; 89.2; 88.4; 89.6 g/L — p=<0.05
N/A N=83 Treatment of Vitamin D Deficiency in Patients With Rheumatoid Arthritis
Rheumatoid Arthritis · Vitamin D Deficiency
Primary: Disease Activity Score (DAS) 28 — 3.4; 2.8; 3.5; 3.1 composite score