N/A N=125 Intraoperative Video Laryngoscopy as Adjunct for Nerve Monitoring
Vocal Cord Function in Neck Procedures
Primary: Frequency of Congruence of Nerve Integrity and Vocal Cord Functions — 68; 13; 17; 10 nerves at risk
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=39 A Novel Approach for Thyroplasty Type 1, With Prolene Mesh. A Prospective Study.
Vocal Cord Paralysis · Phonasthenia · Presbylarynges
Primary: Change in Mean Phonation Time — 7.74; 14.08 seconds
N/A N=55 Phonatory Movement of the Pharyngoesophageal Mucosa in Laryngectomy Patients
Larynx Cancer · Laryngectomy; Status
Primary: High Speed Video Endoscopy Recordings — 53; 2; 2; 38 Participants
N/A N=30 Effect of Semi-occluded Vocal Tract Therapy on the Phonation of Children With Vocal Fold Nodules
Voice Disorders in Children · Vocal Nodules in Children · Hoarseness
Primary: Change in Dysphonia Severity Index — 1.8; 1.8; 0.0 units on a scale — p=0.024
N/A N=100 Evaluation of Video Laryngoscopy in Patients With Head and Neck Pathology
Difficult Intubation
Primary: Number of Participants With Cormack-Lehane Grade >2 Obtained With CMAC D Blade — 37 Participants
N/A N=42 Laryngeal Vibration for Spasmodic Dysphonia
Spasmodic Dysphonia
Primary: Voice Assessment During First Visit — 0.045; 0.17; 0.13; -0.47 decibel
N/A N=20 Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Laser Laryngeal Surgery
Otorhinolaryngologic Surgical Procedures · Laser Therapy
Primary: Lowest Intraoperative Peripheral Oxygen Saturation (SpO2) — 97; 97 percentage of oxygen — p=0.7934
N/A N=11 Efficacy of a Semi-occluded Mask in the Treatment of Patients With Voice Disorders
Voice and Resonance Disorders · Vocal Fold Polyp · Vocal Cord Cyst
Primary: Change From Baseline in VHI-10 Score After 4 Sessions of Voice Therapy — 7 score on a scale — p=.0076
N/A N=20 Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Short Laryngologic Surgery
Laryngologic Surgical Procedures
Primary: Average Oxygen Saturation by Pulse Oximetry (SpO2) (Primary Anesthesia Outcome) — 93; 98.7 percentage of saturation (SpO2) — p=0.006
Phase 3 N=32 Spasmodic Dysphonia Pain
Spasmodic Dysphonia
Primary: Pain Experienced — 2; 2; 2 score on a scale
N/A N=27 Clinical Feasibility of New Tracheoesophageal Puncture Set
Larynx Cancer
Primary: Success Rate of Procedure — 23 Nr part. with succesful insertions
N/A N=30 Evaluating the Feasibility of Acapella® Choice as a Dysphonia Treatment
Muscle Tension Dysphonia · Vocal Fold Palsy · Vocal Cord Paralysis
Primary: Change in Baseline Cepstral/Spectral Index of Dysphonia (CSID) — 1.22; 4.45; 4.56; 3.13 score on a scale
N/A N=58 Voice Therapy With a Semi-occluded Vocal Tract
Voice Disorders
Primary: (Supra)Glottic Activity: Amplitude of Vibration — 37.7; 32.5; 28.8; 37.1 percentage
N/A N=30 MyoVoice to Restore Natural, Hands-free Communication to Individuals With Vocal Impairments
Rehabilitation of Speech and Language Disorders · Speech Disorders · Speech, Alaryngeal
Primary: Pitch Recognition Accuracy — 7.70 Percent agreement to reference pitch
N/A N=31 Controlled Phonation and Vocal Rest Programs After Acute Vocal Exertion in Healthy Adults
Healthy
Primary: Phonation Threshold Pressure — 5.41; 5.08; 6.39; 6.33 cmH20 — p=<0.001
Phase 2 N=27 Bevonescein to Highlight Nerves in Patients Undergoing Head & Neck Surgery
Parotid Neoplasm · Thyroid Neoplasms · Head and Neck Neoplasms
Primary: Safety - The Number of Patients With ALM-488 Related Adverse Events — 0; 0; 0; 0 Participants
N/A N=100 No Post Intubation Laryngeal Symptoms
Sore-throat · Dysphonia · Dysphagia
Primary: Sore Throat on a Scale From 0 (no Sore Throat) to 10 (Worst Possible Sore Throat) — 1.85; 1.9; 1.1; 1.62 score on a scale — p=0.03
Phase 4 N=36 Investigation of the Role of Steroids in Enhancing Voice Therapy Outcomes
Dysphonia
Primary: Change in Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V) Score From Baseline to 2 Months — 0.72; 0.65 score on a scale
N/A N=24 The Effects of Respiratory Training on Voice
Muscle Tension Dysphonia
Primary: Post Training Lung Volume Initiation — 21.07; 27.04 % vital capacity relative to rest level — p=<0.0005
N/A N=170 Robotic Assisted Surgery in Upper Aerodigestive Tract Surgery
Head and Neck Cancer · Oropharyngeal Cancer · Hypopharyngeal Cancer
Primary: Number of Participants With Adequate Exposure and Access to Oropharyngeal and Hypopharyngeal Head and Neck Lesions — 147; 23 participants
N/A N=135 Flexible Intubation Scope With or Without Video Laryngoscope in Supporting Endotracheal Tube Placement in Patients With Head and Neck Cancer Before Surgery
Head and Neck Neoplasm
Primary: Difficult Endotracheal Tube (ETT) Placement — 40; 29; 27; 34 Participants
N/A N=141 Post-operative Sore Throat as Determined by Endotracheal Tube Inflation Technique
Post Operative Sore Throat · Dysphagia · Hoarseness
Primary: Incidence of Tracheopharyngeal Symptoms — 53; 49 participants
N/A N=39 Preliminary Study 2 to Test the Effects of Ambulatory Voice Biofeedback
Vocal Fold Nodules · Muscle Tension Dysphonia
Primary: Percent Compliance — 89.04; 92.44; 90.76 percentage of voicing crossing threshold
N/A N=119 Vivaer® Procedure for Treatment of Nasal Airway Obstruction Study
Nasal Airway Obstruction
Primary: Nasal Obstruction Symptom Evaluation (NOSE) Scale - 3 Month Responder Rate — 88.3; 42.5 percentage of participants
N/A N=29 Preliminary Study 1 to Test the Effects of Ambulatory Voice Biofeedback
Vocal Fold Nodules
Primary: Percent Compliance — 97.38; 95.11; 94.44; 96.08 Percentage of voicing below a threshold
N/A N=450 A New Insertion Technique for Laryngeal Mask Airway
Airway Morbidity
Primary: Number of Subjects Who Present With Postoperative Sore Throat — 71; 71; 67 Participants
Phase 2 N=21 Controlled Study to Evaluate the Safety and Efficacy of Azficel-T for Vocal Fold Scarring and Age-Related Dysphonia
Dysphonia Resulting From Vocal Fold Scarring · Age-related Dysphonia
Primary: Number of Participants With Any Improvement From Baseline in Mucosal Wave Grade — 14; 5 Participants
N/A N=170 Intubating Conditions of Neuromuscular Blockade
Endotracheal Intubation
Primary: Number of Subjects With Optimal Intubating Conditions — 61; 47 Participants — p=0.036
N/A N=96 Vocal Cord Views With the Classical Miller, Wis-Hipple and C-MAC Size 1 Blades in Young Children
Percent of Vocal Cords (Glottic) Opening
Primary: Percentage of Vocal Cord Opening — 100; 98; 100 percent — p=<0.05
Phase 2 N=15 Short-term Clinical Feasibility of the New Provox Vega 22.5 Voice Prosthesis
Total Laryngectomy
Primary: Short-term Feasibility Provox Vega 22.5 French — 15 Patients