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Structured exercise program improves glycemic control and fitness in Bangladeshi adults with type 2 diabetes

Structured exercise program improves glycemic control and fitness in Bangladeshi adults with type 2 …
Photo by Gabin Vallet / Unsplash
Key Takeaway
Consider structured exercise as a feasible short-term adjunct for type 2 diabetes, but long-term effects remain unknown.

A 6-week randomized controlled trial in Bangladesh enrolled 90 adults with type 2 diabetes for over 3 years. The experimental group received a physiotherapist-led structured physical exercise program (3 supervised sessions per week) plus prescribed medication, while the control group received routine medication with lifestyle guidance.

The study found that the exercise group showed greater reductions in capillary blood glucose, greater increases in 6-minute walk test distance, and greater improvements in Short Form-36 quality of life scores compared to the control group. However, the specific effect sizes, absolute numbers, and statistical significance for these outcomes were not reported in the available data.

No serious adverse events occurred during the trial, and adherence to the exercise program was reported as high. Key limitations include the short 6-week follow-up period, which prevents assessment of long-term sustainability and metabolic benefits. The study measured only capillary blood glucose rather than HbA1c, limiting the strength of glycemic control conclusions.

While the RCT design supports causal inference for the intervention effect, and the study used blinded assessors and intention-to-treat analysis, the findings should be interpreted cautiously due to the short duration and unreported effect sizes. The results support the feasibility of structured exercise programs in this population but require longer-term validation.

Study Details

Study typeRct
Sample sizen = 45
EvidenceLevel 2
Follow-up1.4 mo
PublishedApr 2026
View Original Abstract ↓
PURPOSE: The purpose of the study was to investigate the effects of a 6-week physiotherapist-led structured physical exercise program (SPEP) alongside routine medication on glycemic control, physical fitness, and quality of life in adults with type 2 diabetes mellitus (T2DM) in Bangladesh. METHODS: Ninety adults with T2DM for over 3 years were randomly assigned to an experimental (n = 45) or control group (n = 45). The experimental group performed 3 supervised SPEP sessions per week plus prescribed medication, and the control group continued routine medication with lifestyle guidance for 6 weeks. Glycemic control, assessed by capillary blood glucose (CBG), was the primary outcome. Secondary outcomes included physical fitness 6-minute walk test (6MWT), and quality of life (Short Form-36 [SF-36]). Assessments were conducted at baseline and postintervention by blinded assessors, and data were analyzed using the intention-to-treat principle. RESULTS: Baseline characteristics were comparable. Both groups improved across outcomes, with greater gains in the experimental group, including reductions in CBG, increased 6MWT distance, and higher SF-36 scores. Adherence was high, and no serious adverse events occurred. CONCLUSIONS: Six weeks of physiotherapist-led SPEP added to routine medication improved glycemic control, physical fitness, and quality of life in adults with T2DM. These findings support the feasibility and short-term efficacy of structured exercise in this population. Future studies should assess long-term sustainability and metabolic benefits.
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