Multifaceted mechanisms including replication fork stabilization and epigenetic reprogramming drive PARP inhibitor resistance in ovarian cancer
New Strategies May Help Overcome Ovarian Cancer Treatment Resistance
This narrative review explores the mechanisms of resistance to PARP inhibitors in patients with advanced epithelial ovarian cancer. The auth…
Researchers are identifying specific biological mechanisms that cause ovarian cancer to resist PARP inhibitors, opening doors for new treatm…
Platelet-rich fibrin may reduce medication-related osteonecrosis of the jaw risk during tooth extractions
Platelet-rich fibrin may lower jaw bone damage risks
Researchers evaluated the impact of platelet-rich fibrin on patients undergoing tooth extractions while receiving antiresorptive or antiangi…
New data suggests using platelet-rich fibrin during tooth extractions could lower the risk of severe jawbone complications for patients on s…
Systematic review examines immunotherapy resistance mechanisms and strategies in hepatocellular carcinoma patients
Why Liver Cancer Stops Responding to Immunotherapy — and What Could Change That
This systematic review evaluated drug resistance mechanisms and strategies to overcome resistance in patients with hepatocellular carcinoma …
Understanding why liver cancer learns to dodge the immune system's attack is the first step toward treatments that can keep working long-ter…