Allo-HSCT after CAR-T yields sustained remission in DLBCL patient with secondary MDS
CAR-T and transplant may lead to secondary leukemia
This case report and literature review describes a single patient with primary splenic DLBCL who developed secondary myelodysplastic syndrom…
A patient developed a secondary blood cancer after CAR-T therapy and transplant, but a later transplant brought remission.
LDHA promotes malignant progression and drug resistance while modulating tumor-infiltrating immune cell differentiation
New research identifies LDHA as a promising target for cancer
This systematic review examines the role of Lactate dehydrogenase A (LDHA) in malignant tumors and its impact on the immune microenvironment…
A specific protein called LDHA helps tumors grow and resist drugs, making it a potential new target to combine with existing immunotherapies…
Narrative review conceptualizes CVD as systemic immune–metabolic–inflammatory disease
Review suggests immune and metabolic factors drive cardiovascular disease progression
This narrative review synthesizes evidence on cardiovascular disease as a systemic immune–metabolic–inflammatory condition.
Immune and metabolic factors actively drive heart disease progression, offering new ways to assess risk and tailor prevention strategies.