Retrospective analysis of 41,775 reports identifies signals for cognitive disorders with 50 medications including finasteride and diltiazem.
Analysis of 50 drugs shows statistical links to cognitive issues in vulnerable groups
This retrospective disproportionality analysis examined 41,775 reports from the FDA, JADER, and WHO VigiAccess databases (2004–2024) involvi…
74% of 50 drugs linked to cognitive issues in reports lack FDA warnings, with signals stronger in vulnerable groups like children and senior…
Apixaban Plasma Levels Elevated in Medicare Patients Taking CYP3A4 and P-gp Inhibitors
Higher Drug Levels Mean More Bleeding Risk
This pilot cohort study evaluated 35 Medicare patients with atrial fibrillation receiving apixaban 5mg BID. Apixaban plasma concentrations w…
Taking common heart rhythm drugs with apixaban raises blood levels and increases the risk of serious bleeding that can lead to hospitalizati…