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Home › Medications › fluoride

fluoride

4 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of fluoride

21 trials tracked of fluoride: 19 in phase 3 or 4.

21Trials tracked
19Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 3 19 Phase 2 1 Phase 1 1
  1. Phase 3 Train New Examiners Via Modified Gingival Margin Plaque Completed
  2. Phase 3 Evaluate Clinical Research From Commerical Oral Care Products Completed
  3. Phase 3 To Access the Effects of Mucositis in Adults With Dental Implants Completed
  4. Phase 3 Study to Determine the Anti-plaque Efficacy of Commerical Toothpastes and an Oral Rinse Completed
  5. Phase 3 Effect on Bacterial Glycolytic Acid Formation on Plaque Completed
  6. Phase 3 Effectiveness of a Triclosan Containing Toothpaste in Maintaining Periodontal Health in a Type 2 Diabetic Population Completed
Show 15 more trials
  1. Phase 3 Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing. Completed
  2. Phase 3 Efficacy of Salivary Bacteria and Post Brushing Completed
  3. Phase 3 Development of Clinical Method to Triclosan Retention in Plaque Following Brushing Completed
  4. Phase 3 The Effect of Periodontal Treatment and the Use of Dentifrice on Glycaemic Control in Diabetics Completed
  5. Phase 3 Compare the Clinical Efficacy of Prototype Toothpastes. Completed
  6. Phase 3 Comparative Efficacy of a Toothpaste That Reduces Plaque and Gingivitis Completed
  7. Phase 3 Collection of Gingival Crevicular Fluid From Periodontitis Patients Completed
  8. Phase 3 Investigate Oral Bacteria in Adult Population Completed
  9. Phase 3 Clinical Study to Compare Dental Plaque Control Completed
  10. Phase 3 Clinical Study to Evaluate the Treatment of Gingivitis of Two Toothpastes Completed
  11. Phase 3 Compare the Clinical Efficacy of Prototype Toothpastes Completed
  12. Phase 3 Clinical Study to Examine Brushing on Dental Implants Completed
  13. Phase 3 A Clinical Study to Evaluate Experimental Children's Toothpastes in an In-Situ Caries Model Completed
  14. Phase 2 Evaluating Commercial Anti-Plaque Products and Oral Rinse Completed
  15. Phase 1 Effect of Calcium Glycerophosphate (CaGP) - Fluoride Dentifrice on Dental Biofilm pH Completed

Showing the 21 most-cited and recently-updated of 21 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Collaborative oral health management model improves plaque index and quality of life in preschool children
Neurology RCT
Collaborative oral health management model improves plaque index and quality of life in preschool children Collaborative care model improves oral health in preschool children
This prospective single-arm pre-post intervention study of 421 preschool children found that a collaborative management model significantly …
A new collaborative management model involving families, schools, and hospitals helps preschool children improve their oral health and reduc…
Frontiers Oct 9, 2026
Topical fluoride significantly reduces dental caries incidence in children and adolescents with OR 0.27
Pediatrics Meta-analysis
Topical fluoride significantly reduces dental caries incidence in children and adolescents with OR 0.27 Topical fluoride treatments significantly reduce tooth decay in children
This meta-analysis of 10 clinical studies indicates that topical fluoride treatments, including rinses, toothpaste, and varnishes, significa…
Topical fluoride treatments like rinses, gels, and varnishes significantly lower the risk of cavities in children and adolescents.
Sep 30, 2026
Potassium nitrate and photobiomodulation therapy reduce intensity of bleaching-induced tooth sensitivity
Drug Pipeline Sys. Review
Potassium nitrate and photobiomodulation therapy reduce intensity of bleaching-induced tooth sensitivity Potassium Nitrate and Photobiomodulation May Ease Bleaching Tooth Sensitivity
This systematic umbrella review evaluates several interventions for managing bleaching-induced tooth sensitivity. The findings indicate that…
New research highlights how potassium nitrate and photobiomodulation therapy may help manage tooth sensitivity caused by whitening treatment…
Frontiers Sep 22, 2026
Sugar acts as a pivotal ecological factor influencing metabolism, biofilm formation, and interspecies interactions in dental caries
Infectious Disease Sys. Review
Sugar acts as a pivotal ecological factor influencing metabolism, biofilm formation, and interspecies interactions in dental caries New Strategies Help Prevent Dental Caries Through Ecological Management
This narrative review explores the role of dietary sugars and various prevention strategies like fluoride application and probiotics in mana…
Sugar plays a major role in how bacteria build plaque on teeth, but new strategies like probiotics and fluoride may help balance the oral mi…
Frontiers Jun 23, 2026