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Home › Medications › FOLFOX

FOLFOX

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of FOLFOX

11 trials tracked of FOLFOX: 1 in phase 3 or 4 and 1 with published results. The most-cited published study has 110 citations.

11Trials tracked
1Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 3 1 Phase 2 10
  1. Phase 3 Study of Pegilodecakin (LY3500518) With FOLFOX Compared to FOLFOX Alone Second-line Tx in Participants With Metastatic Pancreatic Cancer Completed · 110 cited
  2. Phase 2 Study of Erlotinib and Chemotherapy for Unresectable or Metastatic Cancer of the Esophagus and Gastric Cardia Completed
  3. Phase 2 RAD001, FOLFOX and Bevacizumab in Treatment of Colorectal Carcinoma Completed
  4. Phase 2 Combination Chemotherapy and Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Locally Advanced Rectal Cancer Completed
  5. Phase 2 A Study to Determine the Activity of Robatumumab (SCH 717454, MK-7454) in Participants With Relapsed or Recurrent Colorectal Cancer (P04721, MK-7454-003) Completed
  6. Phase 2 FOLFOX With Bevacizumab in Metastatic or Unresectable Gastroesophageal and Gastric Cancer Completed
Show 5 more trials
  1. Phase 2 An Investigational Study of Immunotherapy Combinations With Chemotherapy in Patients With Gastric or Gastroesophageal Junction (GEJ) Cancers Completed
  2. Phase 2 Study Evaluating the Safety and Efficacy of FOLFIRI Plus Cetuximab or FOLFOX Plus Cetuximab as First-line Therapy in Subjects With KRAS Wild-type Metastatic Colorectal Cancer (APEC-Study) Completed
  3. Phase 2 Phase I/II Trial of Tivantinib With FOLFOX for the Treatment of Advanced Solid Tumors and Previously Untreated Metastatic Adenocarcinoma of the Distal Esophagus, Gastroesophageal Junction or Stomach Completed
  4. Phase 2 A Study of Vismodegib (GDC-0449) in Patients Treated With Vismodegib in a Previous Genentech-sponsored Phase I or II Cancer Study Completed
  5. Phase 2 Combination Chemotherapy and Cetuximab in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer Completed

Showing the 11 most-cited and recently-updated of 11 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Meta-analysis shows bevacizumab plus FOLFOX improves response rates without increasing common toxicities in advanced colorectal cancer
Oncology Meta-analysis
Meta-analysis shows bevacizumab plus FOLFOX improves response rates without increasing common toxicities in advanced colorectal cancer Adding bevacizumab to standard chemo improves tumor response in advanced colorectal cancer
This systematic review and meta-analysis evaluated bevacizumab combined with FOLFOX versus FOLFOX alone in patients with advanced or metasta…
A large review found that adding bevacizumab to standard chemotherapy improves how well tumors respond and keeps disease under control longe…
Frontiers May 21, 2026
Serplulimab with FOLFOX showed disease control in AFP-producing gastric adenocarcinoma with liver metastases
Allergy & Immunology Cohort
Serplulimab with FOLFOX showed disease control in AFP-producing gastric adenocarcinoma with liver metastases Rare Stomach Cancer Shrinks After New Combo Treatment
This case report and literature review describes a 67-year-old man with AFP-producing gastric adenocarcinoma and liver metastases treated wi…
A rare stomach cancer that spread to the liver shrank dramatically when doctors combined standard chemotherapy with a newer immune-boosting …
Frontiers Apr 16, 2026